%PDF-1.6
%
1 0 obj
<<
/AcroForm 2 0 R
/Lang (EN)
/Metadata 3 0 R
/Names 4 0 R
/Outlines 5 0 R
/OutputIntents [6 0 R]
/PageLabels 7 0 R
/PageMode /UseOutlines
/Pages 8 0 R
/Type /Catalog
>>
endobj
9 0 obj
<<
/Author (Selim Bozkurt)
/CreationDate (D:20170401154446+05'30')
/Creator (Springer)
/CrossMarkDomains#5B1#5D (springer.com)
/CrossMarkDomains#5B2#5D (springerlink.com)
/CrossmarkDomainExclusive (true)
/CrossmarkMajorVersionDate (2010-04-23)
/Keywords (Transcatheter mitral valve implantation \(TMVI\),Heart valve development,Heart valve assessment,Mitral valve,Bioprosthetic bi-leaflet valve)
/ModDate (D:20170719074412+05'30')
/Producer (Acrobat Distiller 10.1.8 \(Windows\))
/Subject (Annals of Biomedical Engineering, doi:10.1007/s10439-017-1828-2)
/Title (Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation)
/doi (10.1007/s10439-017-1828-2)
/robots (noindex)
>>
endobj
2 0 obj
<<
/DA (/Helv 0 Tf 0 g )
/DR <<
/Encoding <<
/PDFDocEncoding 10 0 R
>>
/Font <<
/Helv 11 0 R
/ZaDb 12 0 R
>>
>>
/Fields []
>>
endobj
3 0 obj
<<
/Length 31124
/Subtype /XML
/Type /Metadata
>>
stream
2017-04-01T15:44:46+05:30
Springer
2017-07-19T07:44:12+05:30
2017-07-19T07:44:12+05:30
Acrobat Distiller 10.1.8 (Windows)
Transcatheter mitral valve implantation (TMVI),Heart valve development,Heart valve assessment,Mitral valve,Bioprosthetic bi-leaflet valve
application/pdf
doi:10.1007/s10439-017-1828-2
Springer US
Annals of Biomedical Engineering, doi:10.1007/s10439-017-1828-2
Transcatheter mitral valve implantation (TMVI)
Heart valve development
Heart valve assessment
Mitral valve
Bioprosthetic bi-leaflet valve
Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation
Selim Bozkurt
Georgia L. Preston-Maher
Ryo Torii
Gaetano Burriesci
10.1007/s10439-017-1828-2
2010-04-23
true
springer.com
springerlink.com
"http://dx.doi.org/10.1007/s10439-017-1828-2
10.1007/s10439-017-1828-2
1573-9686
45
8
1852
1864
journal
Annals of Biomedical Engineering
The Author(s)
2010-04-23
true
10.1007/s10439-017-1828-2
noindex
springer.com
springerlink.com
VoR
uuid:32051192-690b-4523-b4b1-28565e91b283
uuid:707d2cf2-bd81-49bb-917d-4a3a9399c67f
default
1
converted
uuid:bc512bc9-2fa9-421d-a3de-784ed3f0cb75
converted to PDF/A-2b
pdfToolbox
2017-07-19T07:43:36+05:30
converted
uuid:3e0d3bb0-b03f-4a7a-893a-62e91cea9d56
converted to PDF/A-2b
pdfToolbox
2017-07-19T07:44:12+05:30
2
B
Gaetano Burriesci
http://orcid.org/0000-0002-9213-3403
http://ns.adobe.com/pdfx/1.3/
pdfx
Adobe Document Info PDF eXtension Schema
external
Mirrors crossmark:MajorVersionDate
CrossmarkMajorVersionDate
Text
external
Mirrors crossmark:CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
Mirrors crossmark:DOI
doi
Text
external
Mirrors crossmark:CrosMarkDomains
CrossMarkDomains
seq Text
internal
A name object indicating whether the document has been modified to include trapping information
robots
Text
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://crossref.org/crossmark/1.0/
crossmark
Crossmark Schema
internal
Usual same as prism:doi
DOI
Text
external
The date when a publication was publishe.
MajorVersionDate
Text
internal
CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
CrossMarkDomains
CrossMarkDomains
seq Text
http://prismstandard.org/namespaces/basic/2.0/
prism
Prism Schema
external
This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.
url
URI
external
The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL).
doi
Text
external
ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.
issn
Text
internal
Volume number
volume
Text
internal
Issue number
number
Text
internal
Starting page
startingPage
Text
internal
Ending page
endingPage
Text
external
The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary.
aggregationType
Text
external
Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”
publicationName
Text
external
Copyright
copyright
Text
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
DocumentID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
Springer Nature ORCID Schema
http://springernature.com/ns/xmpExtensions/2.0/
sn
authorInfo
seq AuthorInformation
external
Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
AuthorInformation
http://springernature.com/ns/xmpExtensions/2.0/authorInfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
http://www.niso.org/schemas/jav/1.0/
jav
NISO
external
Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record
journal_article_version
Closed Choice of Text
endstream
endobj
4 0 obj
<<
/Dests 13 0 R
>>
endobj
5 0 obj
<<
/First 14 0 R
/Last 14 0 R
/Type /Outlines
>>
endobj
6 0 obj
<<
/DestOutputProfile 15 0 R
/Info (sRGB IEC61966-2.1)
/OutputCondition (sRGB)
/OutputConditionIdentifier (Custom)
/RegistryName ()
/S /GTS_PDFA1
/Type /OutputIntent
>>
endobj
7 0 obj
<<
/Nums [0 16 0 R]
>>
endobj
8 0 obj
<<
/Count 14
/Kids [17 0 R 18 0 R]
/Type /Pages
>>
endobj
10 0 obj
<<
/Differences [24 /breve /caron /circumflex /dotaccent /hungarumlaut /ogonek /ring /tilde 39
/quotesingle 96 /grave 128 /bullet /dagger /daggerdbl /ellipsis /emdash /endash
/florin /fraction /guilsinglleft /guilsinglright /minus /perthousand /quotedblbase /quotedblleft /quotedblright /quoteleft
/quoteright /quotesinglbase /trademark /fi /fl /Lslash /OE /Scaron /Ydieresis /Zcaron
/dotlessi /lslash /oe /scaron /zcaron 160 /Euro 164 /currency 166
/brokenbar 168 /dieresis /copyright /ordfeminine 172 /logicalnot /.notdef /registered /macron
/degree /plusminus /twosuperior /threesuperior /acute /mu 183 /periodcentered /cedilla /onesuperior
/ordmasculine 188 /onequarter /onehalf /threequarters 192 /Agrave /Aacute /Acircumflex /Atilde
/Adieresis /Aring /AE /Ccedilla /Egrave /Eacute /Ecircumflex /Edieresis /Igrave /Iacute
/Icircumflex /Idieresis /Eth /Ntilde /Ograve /Oacute /Ocircumflex /Otilde /Odieresis /multiply
/Oslash /Ugrave /Uacute /Ucircumflex /Udieresis /Yacute /Thorn /germandbls /agrave /aacute
/acircumflex /atilde /adieresis /aring /ae /ccedilla /egrave /eacute /ecircumflex /edieresis
/igrave /iacute /icircumflex /idieresis /eth /ntilde /ograve /oacute /ocircumflex /otilde
/odieresis /divide /oslash /ugrave /uacute /ucircumflex /udieresis /yacute /thorn /ydieresis]
/Type /Encoding
>>
endobj
11 0 obj
<<
/BaseFont /Helvetica
/Encoding 10 0 R
/Name /Helv
/Subtype /Type1
/Type /Font
>>
endobj
12 0 obj
<<
/BaseFont /ZapfDingbats
/Name /ZaDb
/Subtype /Type1
/Type /Font
>>
endobj
13 0 obj
<<
/Kids [19 0 R 20 0 R]
>>
endobj
14 0 obj
<<
/C [0.0 0.0 0.0]
/Count -8
/Dest (Title)
/F 0
/First 21 0 R
/Last 22 0 R
/Parent 5 0 R
/Title (Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation)
>>
endobj
15 0 obj
<<
/Length 2574
/Filter /FlateDecode
/N 3
/Range [0 1 0 1 0 1]
>>
stream
HyTSwoɞc
[5laQIBHADED2mtFOE.c}088GNg9w߽ '0 ֠Jb
2y.-;!KZ ^i"L0-
@8(r;q7Ly&Qq4j|9
V)gB0iW8#8wթ8_٥ʨQQj@&A)/g>'K t;\
ӥ$պFZUn(4T%)뫔0C&Zi8bxEB;Pӓ̹Aom?W=
x- [ 0}y)7ta>jT7@tܛ`q2ʀ&6ZLĄ?_yxg)˔zçLU*uSkSeO4?c. R
߁-25 S>ӣVd`rn~Y&+`;A4 A9 =-tl`;~p Gp| [`L`< "AYA+Cb(R, *T2B-
ꇆnQt}MA0alSx k&^>0|>_',G!"F$H:R!zFQd?r9\A&GrQhE]a4zBgE#H *B=0HIpp0MxJ$D1D, VĭKĻYdE"EI2EBGt4MzNr!YK ?%_(0J:EAiQ(()ӔWT6U@P+!~mDeԴ!hӦh/']B/ҏӿ?a0nhF!X8܌kc&5S6lIa2cKMA!E#ƒdV(kel
}}Cq9
N')].uJr
wG xR^[oƜchg`>b$*~ :Eb~,m,-ݖ,Y¬*6X[ݱF=3뭷Y~dó tizf6~`{v.Ng#{}}jc1X6fm;'_9 r:8q:˜O:ϸ8uJqnv=MmR 4
n3ܣkGݯz=[==<=GTB(/S,]6*-W:#7*e^YDY}UjAyT`#D="b{ų+ʯ:!kJ4Gmt}uC%K7YVfFY.=b?SƕƩȺy
چk5%4m7lqlioZlG+Zzmzy]?uuw|"űNwW&e֥ﺱ*|j5kyݭǯg^ykEklD_p߶7Dmo꿻1ml{Mś
nLl<9O [$h՛BdҞ@iءG&vVǥ8nRĩ7u\ЭD- u`ֲK³8%yhYѹJº;.!
zpg_XQKFAǿ=ȼ:ɹ8ʷ6˶5̵5͵6ζ7ϸ9к<Ѿ?DINU\dlvۀ܊ݖޢ)߯6DScs
2F[p(@Xr4Pm8Ww)Km
endstream
endobj
16 0 obj
<<
/S /D
/St 1852
>>
endobj
17 0 obj
<<
/Count 11
/Kids [23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R
33 0 R]
/Parent 8 0 R
/Type /Pages
>>
endobj
18 0 obj
<<
/Count 3
/Kids [34 0 R 35 0 R 36 0 R]
/Parent 8 0 R
/Type /Pages
>>
endobj
19 0 obj
<<
/Limits [(Abs1) (lCR55)]
/Names [(Abs1) 37 0 R (Acknowledgements) 38 0 R (Bib1) 39 0 R (Sec1) 40 0 R (Sec2) 41 0 R
(Sec3) 42 0 R (Sec4) 43 0 R (Sec5) 44 0 R (Sec6) 45 0 R (Sec7) 46 0 R
(Sec8) 47 0 R (Sec9) 48 0 R (Title) 49 0 R (lCR1) 50 0 R (lCR10) 51 0 R
(lCR11) 52 0 R (lCR12) 53 0 R (lCR13) 54 0 R (lCR14) 55 0 R (lCR15) 56 0 R
(lCR16) 57 0 R (lCR17) 58 0 R (lCR18) 59 0 R (lCR19) 60 0 R (lCR2) 61 0 R
(lCR20) 62 0 R (lCR21) 63 0 R (lCR22) 64 0 R (lCR23) 65 0 R (lCR24) 66 0 R
(lCR25) 67 0 R (lCR26) 68 0 R (lCR27) 69 0 R (lCR28) 70 0 R (lCR29) 71 0 R
(lCR3) 72 0 R (lCR30) 73 0 R (lCR31) 74 0 R (lCR32) 75 0 R (lCR33) 76 0 R
(lCR34) 77 0 R (lCR35) 78 0 R (lCR36) 79 0 R (lCR37) 80 0 R (lCR38) 81 0 R
(lCR39) 82 0 R (lCR4) 83 0 R (lCR40) 84 0 R (lCR41) 85 0 R (lCR42) 86 0 R
(lCR43) 87 0 R (lCR44) 88 0 R (lCR45) 89 0 R (lCR46) 90 0 R (lCR47) 91 0 R
(lCR48) 92 0 R (lCR49) 93 0 R (lCR5) 94 0 R (lCR50) 95 0 R (lCR51) 96 0 R
(lCR52) 97 0 R (lCR53) 98 0 R (lCR54) 99 0 R (lCR55) 100 0 R]
>>
endobj
20 0 obj
<<
/Limits [(lCR56) (lSec9)]
/Names [(lCR56) 101 0 R (lCR57) 102 0 R (lCR58) 103 0 R (lCR59) 104 0 R (lCR6) 105 0 R
(lCR60) 106 0 R (lCR61) 107 0 R (lCR7) 108 0 R (lCR8) 109 0 R (lCR9) 110 0 R
(lEqu1) 111 0 R (lEqu2) 112 0 R (lFig1) 113 0 R (lFig2) 114 0 R (lFig3) 115 0 R
(lFig4) 116 0 R (lFig5) 117 0 R (lFig6) 118 0 R (lFig7) 119 0 R (lFig8) 120 0 R
(lSec1) 121 0 R (lSec2) 122 0 R (lSec3) 123 0 R (lSec4) 124 0 R (lSec5) 125 0 R
(lSec6) 126 0 R (lSec7) 127 0 R (lSec8) 128 0 R (lSec9) 129 0 R]
>>
endobj
21 0 obj
<<
/C [0.0 0.0 0.0]
/Count 0
/Dest (Abs1)
/F 0
/Next 130 0 R
/Parent 14 0 R
/Title (Abstract)
>>
endobj
22 0 obj
<<
/C [0.0 0.0 0.0]
/Count 0
/Dest (Bib1)
/F 0
/Parent 14 0 R
/Prev 131 0 R
/Title (References)
>>
endobj
23 0 obj
<<
/Contents 132 0 R
/Type /Page
/Resources <<
/Font <<
/F1 133 0 R
/F2 134 0 R
/F3 135 0 R
>>
/XObject <<
/Xf1 136 0 R
>>
>>
/Annots [137 0 R 138 0 R 139 0 R]
/Parent 17 0 R
/MediaBox [0 0 595 842]
>>
endobj
24 0 obj
<<
/Annots [140 0 R 141 0 R 142 0 R 143 0 R 144 0 R 145 0 R 146 0 R 147 0 R 148 0 R 149 0 R
150 0 R 151 0 R 152 0 R 153 0 R 154 0 R 155 0 R 156 0 R 157 0 R 158 0 R 159 0 R]
/Contents [160 0 R 161 0 R 162 0 R 163 0 R 164 0 R 165 0 R 166 0 R 167 0 R]
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 168 0 R
/Rotate 0
/Thumb 169 0 R
/Type /Page
>>
endobj
25 0 obj
<<
/Annots [170 0 R 171 0 R 172 0 R 173 0 R 174 0 R 175 0 R 176 0 R 177 0 R 178 0 R 179 0 R
180 0 R 181 0 R 182 0 R 183 0 R 184 0 R 185 0 R 186 0 R 187 0 R 188 0 R 189 0 R
190 0 R]
/Contents 191 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 192 0 R
/Rotate 0
/Thumb 193 0 R
/Type /Page
>>
endobj
26 0 obj
<<
/Annots [194 0 R 195 0 R 196 0 R 197 0 R]
/Contents 198 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 199 0 R
/Rotate 0
/Thumb 200 0 R
/Type /Page
>>
endobj
27 0 obj
<<
/Annots [201 0 R 202 0 R 203 0 R 204 0 R 205 0 R 206 0 R 207 0 R 208 0 R 209 0 R 210 0 R
211 0 R 212 0 R]
/Contents 213 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 214 0 R
/Rotate 0
/Thumb 215 0 R
/Type /Page
>>
endobj
28 0 obj
<<
/Annots [216 0 R 217 0 R 218 0 R 219 0 R 220 0 R]
/Contents 221 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 222 0 R
/Rotate 0
/Thumb 223 0 R
/Type /Page
>>
endobj
29 0 obj
<<
/Annots [224 0 R 225 0 R 226 0 R 227 0 R 228 0 R 229 0 R 230 0 R 231 0 R]
/Contents 232 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 233 0 R
/Rotate 0
/Thumb 234 0 R
/Type /Page
>>
endobj
30 0 obj
<<
/Annots [235 0 R 236 0 R]
/Contents 237 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 238 0 R
/Rotate 0
/Thumb 239 0 R
/Type /Page
>>
endobj
31 0 obj
<<
/Annots [240 0 R 241 0 R 242 0 R 243 0 R 244 0 R 245 0 R 246 0 R 247 0 R 248 0 R 249 0 R
250 0 R]
/Contents 251 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 252 0 R
/Rotate 0
/Thumb 253 0 R
/Type /Page
>>
endobj
32 0 obj
<<
/Annots [254 0 R 255 0 R]
/Contents 256 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 257 0 R
/Rotate 0
/Thumb 258 0 R
/Type /Page
>>
endobj
33 0 obj
<<
/Annots [259 0 R 260 0 R 261 0 R 262 0 R 263 0 R 264 0 R 265 0 R 266 0 R 267 0 R 268 0 R
269 0 R 270 0 R 271 0 R 272 0 R 273 0 R 274 0 R 275 0 R 276 0 R]
/Contents 277 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 17 0 R
/Resources 278 0 R
/Rotate 0
/Thumb 279 0 R
/Type /Page
>>
endobj
34 0 obj
<<
/Annots [280 0 R 281 0 R 282 0 R 283 0 R 284 0 R]
/Contents 285 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 18 0 R
/Resources 286 0 R
/Rotate 0
/Thumb 287 0 R
/Type /Page
>>
endobj
35 0 obj
<<
/Contents 288 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 18 0 R
/Resources 289 0 R
/Rotate 0
/Thumb 290 0 R
/Type /Page
>>
endobj
36 0 obj
<<
/Annots [291 0 R]
/Contents 292 0 R
/CropBox [0.0 0.0 593.972 792.0]
/MediaBox [0.0 0.0 593.972 792.0]
/Parent 18 0 R
/Resources 293 0 R
/Rotate 0
/Thumb 294 0 R
/Type /Page
>>
endobj
37 0 obj
<<
/D [24 0 R /FitR 0 537 594 537]
>>
endobj
38 0 obj
<<
/D [34 0 R /FitR 0 492 569 0]
>>
endobj
39 0 obj
<<
/D [34 0 R /FitR 0 756 594 756]
>>
endobj
40 0 obj
<<
/D [24 0 R /FitR 0 216 594 216]
>>
endobj
41 0 obj
<<
/D [25 0 R /FitR 0 302 594 302]
>>
endobj
42 0 obj
<<
/D [25 0 R /FitR 0 281 594 281]
>>
endobj
43 0 obj
<<
/D [26 0 R /FitR 0 208 594 208]
>>
endobj
44 0 obj
<<
/D [28 0 R /FitR 0 756 594 756]
>>
endobj
45 0 obj
<<
/D [28 0 R /FitR 0 523 594 523]
>>
endobj
46 0 obj
<<
/D [29 0 R /FitR 0 586 594 586]
>>
endobj
47 0 obj
<<
/D [30 0 R /FitR 0 145 594 145]
>>
endobj
48 0 obj
<<
/D [33 0 R /FitR 0 146 594 146]
>>
endobj
49 0 obj
<<
/D [24 0 R /FitR 0 717 594 717]
>>
endobj
50 0 obj
<<
/D [34 0 R /FitR 0 729 594 729]
>>
endobj
51 0 obj
<<
/D [34 0 R /FitR 0 201 594 201]
>>
endobj
52 0 obj
<<
/D [34 0 R /FitR 0 172 594 172]
>>
endobj
53 0 obj
<<
/D [35 0 R /FitR 0 755 594 755]
>>
endobj
54 0 obj
<<
/D [35 0 R /FitR 0 735 594 735]
>>
endobj
55 0 obj
<<
/D [35 0 R /FitR 0 685 594 685]
>>
endobj
56 0 obj
<<
/D [35 0 R /FitR 0 635 594 635]
>>
endobj
57 0 obj
<<
/D [35 0 R /FitR 0 606 594 606]
>>
endobj
58 0 obj
<<
/D [35 0 R /FitR 0 556 594 556]
>>
endobj
59 0 obj
<<
/D [35 0 R /FitR 0 506 594 506]
>>
endobj
60 0 obj
<<
/D [35 0 R /FitR 0 436 594 436]
>>
endobj
61 0 obj
<<
/D [34 0 R /FitR 0 660 594 660]
>>
endobj
62 0 obj
<<
/D [35 0 R /FitR 0 396 594 396]
>>
endobj
63 0 obj
<<
/D [35 0 R /FitR 0 337 594 337]
>>
endobj
64 0 obj
<<
/D [35 0 R /FitR 0 287 594 287]
>>
endobj
65 0 obj
<<
/D [35 0 R /FitR 0 207 594 207]
>>
endobj
66 0 obj
<<
/D [35 0 R /FitR 0 177 594 177]
>>
endobj
67 0 obj
<<
/D [35 0 R /FitR 0 735 594 735]
>>
endobj
68 0 obj
<<
/D [35 0 R /FitR 0 715 594 715]
>>
endobj
69 0 obj
<<
/D [35 0 R /FitR 0 655 594 655]
>>
endobj
70 0 obj
<<
/D [35 0 R /FitR 0 635 594 635]
>>
endobj
71 0 obj
<<
/D [35 0 R /FitR 0 586 594 586]
>>
endobj
72 0 obj
<<
/D [34 0 R /FitR 0 600 594 600]
>>
endobj
73 0 obj
<<
/D [35 0 R /FitR 0 536 594 536]
>>
endobj
74 0 obj
<<
/D [35 0 R /FitR 0 466 594 466]
>>
endobj
75 0 obj
<<
/D [35 0 R /FitR 0 426 594 426]
>>
endobj
76 0 obj
<<
/D [35 0 R /FitR 0 386 594 386]
>>
endobj
77 0 obj
<<
/D [35 0 R /FitR 0 357 594 357]
>>
endobj
78 0 obj
<<
/D [35 0 R /FitR 0 327 594 327]
>>
endobj
79 0 obj
<<
/D [35 0 R /FitR 0 237 594 237]
>>
endobj
80 0 obj
<<
/D [35 0 R /FitR 0 197 594 197]
>>
endobj
81 0 obj
<<
/D [35 0 R /FitR 0 127 594 127]
>>
endobj
82 0 obj
<<
/D [36 0 R /FitR 0 725 594 725]
>>
endobj
83 0 obj
<<
/D [34 0 R /FitR 0 500 594 500]
>>
endobj
84 0 obj
<<
/D [36 0 R /FitR 0 635 594 635]
>>
endobj
85 0 obj
<<
/D [36 0 R /FitR 0 616 594 616]
>>
endobj
86 0 obj
<<
/D [36 0 R /FitR 0 586 594 586]
>>
endobj
87 0 obj
<<
/D [36 0 R /FitR 0 516 594 516]
>>
endobj
88 0 obj
<<
/D [36 0 R /FitR 0 486 594 486]
>>
endobj
89 0 obj
<<
/D [36 0 R /FitR 0 426 594 426]
>>
endobj
90 0 obj
<<
/D [36 0 R /FitR 0 376 594 376]
>>
endobj
91 0 obj
<<
/D [36 0 R /FitR 0 347 594 347]
>>
endobj
92 0 obj
<<
/D [36 0 R /FitR 0 277 594 277]
>>
endobj
93 0 obj
<<
/D [36 0 R /FitR 0 237 594 237]
>>
endobj
94 0 obj
<<
/D [34 0 R /FitR 0 460 594 460]
>>
endobj
95 0 obj
<<
/D [36 0 R /FitR 0 755 594 755]
>>
endobj
96 0 obj
<<
/D [36 0 R /FitR 0 725 594 725]
>>
endobj
97 0 obj
<<
/D [36 0 R /FitR 0 665 594 665]
>>
endobj
98 0 obj
<<
/D [36 0 R /FitR 0 616 594 616]
>>
endobj
99 0 obj
<<
/D [36 0 R /FitR 0 576 594 576]
>>
endobj
100 0 obj
<<
/D [36 0 R /FitR 0 516 594 516]
>>
endobj
101 0 obj
<<
/D [36 0 R /FitR 0 466 594 466]
>>
endobj
102 0 obj
<<
/D [36 0 R /FitR 0 416 594 416]
>>
endobj
103 0 obj
<<
/D [36 0 R /FitR 0 366 594 366]
>>
endobj
104 0 obj
<<
/D [36 0 R /FitR 0 317 594 317]
>>
endobj
105 0 obj
<<
/D [34 0 R /FitR 0 381 594 381]
>>
endobj
106 0 obj
<<
/D [36 0 R /FitR 0 287 594 287]
>>
endobj
107 0 obj
<<
/D [36 0 R /FitR 0 237 594 237]
>>
endobj
108 0 obj
<<
/D [34 0 R /FitR 0 341 594 341]
>>
endobj
109 0 obj
<<
/D [34 0 R /FitR 0 301 594 301]
>>
endobj
110 0 obj
<<
/D [34 0 R /FitR 0 231 594 231]
>>
endobj
111 0 obj
<<
/D [26 0 R /FitR 0 249 594 249]
>>
endobj
112 0 obj
<<
/D [29 0 R /FitR 0 715 594 715]
>>
endobj
113 0 obj
<<
/D [26 0 R /FitR 0 506 594 506]
>>
endobj
114 0 obj
<<
/D [27 0 R /FitR 0 108 594 108]
>>
endobj
115 0 obj
<<
/D [28 0 R /FitR 0 126 594 126]
>>
endobj
116 0 obj
<<
/D [29 0 R /FitR 0 117 594 117]
>>
endobj
117 0 obj
<<
/D [30 0 R /FitR 0 520 594 520]
>>
endobj
118 0 obj
<<
/D [30 0 R /FitR 0 318 594 318]
>>
endobj
119 0 obj
<<
/D [31 0 R /FitR 0 604 594 604]
>>
endobj
120 0 obj
<<
/D [32 0 R /FitR 0 187 594 187]
>>
endobj
121 0 obj
<<
/D [24 0 R /FitR 0 216 594 216]
>>
endobj
122 0 obj
<<
/D [25 0 R /FitR 0 302 594 302]
>>
endobj
123 0 obj
<<
/D [25 0 R /FitR 0 281 594 281]
>>
endobj
124 0 obj
<<
/D [26 0 R /FitR 0 208 594 208]
>>
endobj
125 0 obj
<<
/D [28 0 R /FitR 0 756 594 756]
>>
endobj
126 0 obj
<<
/D [28 0 R /FitR 0 523 594 523]
>>
endobj
127 0 obj
<<
/D [29 0 R /FitR 0 586 594 586]
>>
endobj
128 0 obj
<<
/D [30 0 R /FitR 0 145 594 145]
>>
endobj
129 0 obj
<<
/D [33 0 R /FitR 0 146 594 146]
>>
endobj
130 0 obj
<<
/C [0.0 0.0 0.0]
/Count 0
/Dest (Sec1)
/F 0
/Next 295 0 R
/Parent 14 0 R
/Prev 21 0 R
/Title (Introduction)
>>
endobj
131 0 obj
<<
/C [0.0 0.0 0.0]
/Count 0
/Dest (Acknowledgements)
/F 0
/Next 22 0 R
/Parent 14 0 R
/Prev 296 0 R
/Title (Acknowledgements)
>>
endobj
132 0 obj
<<
/Length 1238
/Filter /FlateDecode
>>
stream
xU[S"G*AKdcU?RS3 V)/,"40Yſw8l8NOӧ;ԥ-RQ@eGޥҏ_iMsYsl7+/a33CB!Llxi-3'OW7LQ-QN ߲0TP3D]|fkJ
md')Q/R]8iϖ-`m%۱_mְ@!PAY5sna̴ ><#9UTfM,>=EdT
ǣ >#c%3$[Yt霮sq3LV@kG[s~+]Ĩ;JEqR4'Z_-3g+z!SJ&>Q~
6=xbK^}X0mF[bOl !5un ṂN # ;x7«+$-=Bq9)1)(F- 㴫.cE.LBEXrMyNۊ]&\F.?+5dc r|89k{tm'P'{IUP_x,Q!$q69's-X${s;`$in6>)Ws"s~;
:
x
Lҡ=;o6
l5s'Y$i Qpy<Ȟe#TYY| lcYQvPEe9ˁ`vV,W[ݱ˔ͱ(O6mk<
+_^o$o/ ˗
LV}ٝ_3F9;GҴT"'{3 738/z }vazo`fh!E#3OJj6@&4Il?]ǛF)s=gqveN(q '\9N@R*e'%K[-
퇞BJ \e:}lUrN^M8Ǥ5uI$O@y N(s&YziIx3쪱&Дr313Z`9X#!0{8p⇮˄_WKi&}Y|6Qtoo
_mU`vj9]0;bw!߿P
endstream
endobj
133 0 obj
<<
/Subtype /Type0
/Type /Font
/BaseFont /IVHLFJ+ArialUnicodeMS
/Encoding /Identity-H
/DescendantFonts [297 0 R]
/ToUnicode 298 0 R
>>
endobj
134 0 obj
<<
/Subtype /Type1
/Type /Font
/BaseFont /Helvetica-Bold
/Encoding /WinAnsiEncoding
>>
endobj
135 0 obj
<<
/Subtype /Type1
/Type /Font
/BaseFont /Helvetica
/Encoding /WinAnsiEncoding
>>
endobj
136 0 obj
<<
/Length 398
/Subtype /Form
/Filter /FlateDecode
/Type /XObject
/Matrix [1 0 0 1 0 0]
/FormType 1
/Resources <<
/ExtGState <<
/GS9 299 0 R
/GS6 300 0 R
>>
/ProcSet [/PDF /Text /ImageB /ImageC /ImageI]
/XObject <<
/Image5 301 0 R
>>
/Font <<
/F1 302 0 R
/F2 303 0 R
>>
>>
/BBox [0 0 594.96 842.04]
>>
stream
xMKArlC?,e+C_=X)ٽ̈́PhT_O31LfS
A7UlAyLQttw{O[U`~=uSW뮅;kKUR"*C ^ɪԸ0sٱHԅ!FXn
..
U=`KUK"$\.%X們0,ʂQ&̬O`apeaXfha@H7 y&d3&^35SXI[,)3PF#d!?ĈG&,XY#8XcXd C,[f7@Vx2VxO #
endstream
endobj
137 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1007/s10439-017-1828-2)
>>
/Subtype /Link
/C [0 0 1]
/Border [0 0 0]
/Rect [57 500 246.47 510]
>>
endobj
138 0 obj
<<
/A <<
/S /URI
/URI (https://pure.ulster.ac.uk/en/publications/0239e28d-3e9a-4aa2-b647-ed4ea34f925b)
>>
/Subtype /Link
/C [0 0 1]
/Border [0 0 0]
/Rect [57 460 328.61 470]
>>
endobj
139 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1007/s10439-017-1828-2)
>>
/Subtype /Link
/C [0 0 1]
/Border [0 0 0]
/Rect [57 340 183.17 350]
>>
endobj
140 0 obj
<<
/A <<
/S /URI
/URI (http://orcid.org/0000-0002-9213-3403)
>>
/AP <<
/N 304 0 R
>>
/Border [0 0 0]
/F 4
/Rect [486.765 637.795 495.212 648.737]
/Subtype /Link
/Type /Annot
>>
endobj
141 0 obj
<<
/AP <<
/N 305 0 R
>>
/Border [0 0 0]
/Dest (lCR27)
/F 4
/Rect [207.666 161.235 215.15 171.213]
/Subtype /Link
/Type /Annot
>>
endobj
142 0 obj
<<
/AP <<
/N 306 0 R
>>
/Border [0 0 0]
/Dest (lCR15)
/F 4
/Rect [465.392 492.945 472.875 502.923]
/Subtype /Link
/Type /Annot
>>
endobj
143 0 obj
<<
/AP <<
/N 307 0 R
>>
/Border [0 0 0]
/Dest (lCR40)
/F 4
/Rect [505.134 445.153 512.617 455.131]
/Subtype /Link
/Type /Annot
>>
endobj
144 0 obj
<<
/AP <<
/N 308 0 R
>>
/Border [0 0 0]
/Dest (lCR11)
/F 4
/Rect [521.915 433.19 529.398 443.168]
/Subtype /Link
/Type /Annot
>>
endobj
145 0 obj
<<
/AP <<
/N 309 0 R
>>
/Border [0 0 0]
/Dest (lCR30)
/F 4
/Rect [534.614 421.228 542.097 431.206]
/Subtype /Link
/Type /Annot
>>
endobj
146 0 obj
<<
/AP <<
/N 310 0 R
>>
/Border [0 0 0]
/Dest (lCR54)
/F 4
/Rect [534.614 397.304 542.097 407.282]
/Subtype /Link
/Type /Annot
>>
endobj
147 0 obj
<<
/AP <<
/N 311 0 R
>>
/Border [0 0 0]
/Dest (lCR3)
/F 4
/Rect [389.253 373.436 392.995 383.357]
/Subtype /Link
/Type /Annot
>>
endobj
148 0 obj
<<
/AP <<
/N 312 0 R
>>
/Border [0 0 0]
/Dest (lCR20)
/F 4
/Rect [534.614 373.436 542.097 383.357]
/Subtype /Link
/Type /Annot
>>
endobj
149 0 obj
<<
/AP <<
/N 313 0 R
>>
/Border [0 0 0]
/Dest (lCR19)
/F 4
/Rect [525.09 337.55 532.573 347.527]
/Subtype /Link
/Type /Annot
>>
endobj
150 0 obj
<<
/AP <<
/N 314 0 R
>>
/Border [0 0 0]
/Dest (lCR20)
/F 4
/Rect [534.614 337.55 542.097 347.527]
/Subtype /Link
/Type /Annot
>>
endobj
151 0 obj
<<
/AP <<
/N 315 0 R
>>
/Border [0 0 0]
/Dest (lCR5)
/F 4
/Rect [409.776 277.795 413.518 287.716]
/Subtype /Link
/Type /Annot
>>
endobj
152 0 obj
<<
/AP <<
/N 316 0 R
>>
/Border [0 0 0]
/Dest (lCR49)
/F 4
/Rect [415.502 277.795 422.986 287.716]
/Subtype /Link
/Type /Annot
>>
endobj
153 0 obj
<<
/AP <<
/N 317 0 R
>>
/Border [0 0 0]
/Dest (lCR7)
/F 4
/Rect [376.498 229.946 380.239 239.924]
/Subtype /Link
/Type /Annot
>>
endobj
154 0 obj
<<
/AP <<
/N 318 0 R
>>
/Border [0 0 0]
/Dest (lCR34)
/F 4
/Rect [370.488 194.117 377.972 204.038]
/Subtype /Link
/Type /Annot
>>
endobj
155 0 obj
<<
/AP <<
/N 319 0 R
>>
/Border [0 0 0]
/Dest (lCR25)
/F 4
/Rect [363.231 146.268 370.715 156.246]
/Subtype /Link
/Type /Annot
>>
endobj
156 0 obj
<<
/AP <<
/N 320 0 R
>>
/Border [0 0 0]
/Dest (lCR21)
/F 4
/Rect [345.26 110.381 352.743 120.359]
/Subtype /Link
/Type /Annot
>>
endobj
157 0 obj
<<
/AP <<
/N 321 0 R
>>
/Border [0 0 0]
/Dest (lCR36)
/F 4
/Rect [354.727 110.381 362.211 120.359]
/Subtype /Link
/Type /Annot
>>
endobj
158 0 obj
<<
/A <<
/S /URI
/URI (http://crossmark.crossref.org/dialog/?doi=10.1007/s10439-017-1828-2&domain=pdf)
>>
/AP <<
/N 322 0 R
>>
/Border [0 0 0]
/F 4
/Rect [468.283 744.605 499.805 785.48]
/Subtype /Link
/Type /Annot
>>
endobj
159 0 obj
<<
/A <<
/S /URI
/URI (http://crossmark.crossref.org/dialog/?doi=10.1007/s10439-017-1828-2&domain=pdf)
>>
/AP <<
/N 323 0 R
>>
/Border [0 0 0]
/F 4
/Rect [499.805 751.124 544.365 766.034]
/Subtype /Link
/Type /Annot
>>
endobj
160 0 obj
<<
/Length 20319
/Filter /FlateDecode
>>
stream
HWr}WGsA,sڕlGd (#UݜƀH&ehtt>3}t?yn]\~#1njn>y3Qx8%1L 33/x3F:?*e)\Vi-9 (IZ-H$RnWyvEDb=L~2XoI{5-12X7AyVmv0A+l.o9y$N7!im":K;kBqZiե]QWXC^Y5^1as7Z0!x~9f'L8p)8ovs}BywľP}\C?).ìD24^gXuAqrb* )֭eJAX aS`>}<)wZs
ev|)Iť¨}xS`rAMc>8ϜI˟fw'xdK".P#$I\sD}ݑ+dZrۧS+4J9e~̺VPcʻSX 0~Wc$Ӡ;pAhj*$h/?(MTcީeUHl>"_*+1~jtId/}ї堝rzqPG/M>uTp1iŅ(`#3lEt?GdhAiYw*~<,A#(Sf'FSKc Iܭsb9d*q+bEߚ^gh B>㽙_v)M hAB>Lz7f`x>Fѕ6'Va"ЕBzwZ @JCē11h
Q[7 hNBbǽYzcNbFK\Tb~hE~ C-m=@D_ieyA<,f{v{yT-`ASJA[I$0$ɱ-`m [Ԧt -&%)3+J:IŤԉW7gS,olVEF#5}ꩨ~NߒhU,9mM6a~DvUz>MK39oڢ{/U]SN*2~SWһXu/_ČV?&YoD
w !=( y
ÖQkLH&QeIf$J's\~y$@hg;LGƻއ+>@?֛j_IH8;8CCSoC%sZͪ x7\vT8P
0%irlsy=,6˳).cp)<=V7ZX'M8 EGJ,_wfbgDFn&[2:7:כhA"UW%BtDy{\7EwaE<,nPWbZD(z{ٶuVgfmt
6d(P!#MWuP,ƸSɲ"\Nzӯ[qɟkI8}EvKʜ
h!8/J#p exh&ͺ^ǔyD>GPyL؊<`yrHmg UT?m7i!ڞPH51I%YZ!ER
=Ymm@sZ>wI*:|I½dM`v-bq`a-9zv
,}&_E}9eq/0}w'gz2#|*e
SbbizZAL|~MnnzlyuR{'} '}(Qp{qW s"iI'ǂhkZw
hq|nĤ@<[j`L31)_t`K)\6i9m(cL͛j3)C4{&-igdVoJn
Q+;LcN2[xIX1F|农bFPel4p
> $3(%4APS
p/qV+hcOo-]H<}]Z'fںex1A80۫Iu$a[vMP:"o~q 3dyhhK*sqI6o4Fl0@^T?%j&V=S8?ҫem+TYrM&5WbO*Q2@$$" Z"s%临ht{yX^8Ȯц|kJ+: N!,&T%ДL`C3P$Mn||>WjrNba@2nWC]Il/HnQPO}<#wŘ#:~wo/A]Zq<@:)@H>Ddnn(BNp *OM_?.yo>NФrҥbCu__1 䃵ՐD1iSojp@x:Ttϋde93n]oha7m4$иHSw DQ2ͮؿ!O|ʧ\GӘXdL;fC|J)."(-XP*F,x2P3u}(q,3]N%OW'7jwV]ZLůh}Mӣ$ňwh6?.?ZJOWdhfdEOF J0/i^vM!c3o-z4^q9vù
a5YM_Xd<כlqfcrH[,I/2KV@M㌰#8q??G߿H=[ݯc#`NcS=Oo}7v O5qw\M;Nfksv)rJX0#ۺGv>9\x/35/% JX9i|!moVc\7\˹6C%#(k>NO
aBQȰgxPEq.5#^7I
FÉB,>dA
slNe-4hԹ!/=7nvO`P-. B{}yP^>C]
}6#(G'S,ח\j> SeA4[&\zj#<҂[dę_K`i,rVl9Y"\1Lc3}&$
w?7W7miDx(2L~ȋ-QGuB_ZOs;rA9zm.!֝B
uTMXxj;OF¯zoK.\nLuSj3Cs@m~pn弲x"N/s0}ȵ(' .9dR(
T9As`~R=}sm
ÓaY߉a"Jt/ɥ@
VnVwOHxeD S{_|
+]AA j
vz2!*ZeAEc퓾s!Fտ5蹹=9}sLU34ң6UaEP0q۵)=(ؐކ<[dj
m==O_58Tyw[Gs;&9P]YMNdoñ}<詍y'¡LR5 ;KtpS9P٠{O{ܬS&QECw6rCZSzסE='+]Czȫ6|=lЮj}PF5XĈAYWp}g
`ҥ%?HD^'%\ԱHmu0iZM{6TDx}N˲9#اC^~4%녟sqeP"i^ +u廓GLn~uƠ exVM+
ӈ ÁR.ʧE|ڛ'7j=z..-
}lP=7j1\@V0pt(}4^q6J`1v!Ζ LF,#4'FrUj;C @Zr0HU}!gb>Y(Fg4Qodj7u/q2]G@9cEqAJd azuj>`gzО