Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial

Joshua J. Todd, Emeir M McSorley, L. Kirsty Pourshahidi, Sharon M. Madigan, Eamon Laird, Martin Healy, Pamela Magee

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

PURPOSE:Vitamin D inadequacy is a global health concern in athletes as well as the general population. Whilst the role of vitamin D in skeletal health is well defined, there remains uncertainty over whether vitamin D supplementation has an added benefit beyond bone health.METHODS:This randomised placebo-controlled trial in healthy male and female Gaelic footballers (n = 42) investigated the effect of vitamin D3 supplementation [3000 IU (75 µg) daily for 12 weeks, via an oral spray solution] on VO2 max which was the primary outcome measure. Secondary outcomes included skeletal muscle and lung function.RESULTS:Supplementation significantly increased total 25-hydroxyvitamin D concentrations compared to the placebo group (mean ± SD change from baseline, 36.31 ± 32.34 vs. 6.11 ± 23.93 nmol/L, respectively; P = 0.006). At baseline, 50 and 22 % of footballers presented with vitamin D insufficiency (31-49 nmol/L) and deficiency (
LanguageEnglish
Pages1577-1587
Number of pages10
JournalEuropean Journal of Nutrition
Volume56
Issue number4
Early online date25 Mar 2016
DOIs
Publication statusPublished - Jun 2017

Fingerprint

Oral Sprays
Cholecalciferol
Vitamin D
Placebos
Health
Athletes
Uncertainty
Skeletal Muscle
Randomized Controlled Trials
Outcome Assessment (Health Care)
Bone and Bones
Lung
Population

Keywords

  • Athletes
  • Football
  • Randomised controlled trial
  • VO2 max
  • Vitamin D

Cite this

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title = "Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial",
abstract = "PURPOSE:Vitamin D inadequacy is a global health concern in athletes as well as the general population. Whilst the role of vitamin D in skeletal health is well defined, there remains uncertainty over whether vitamin D supplementation has an added benefit beyond bone health.METHODS:This randomised placebo-controlled trial in healthy male and female Gaelic footballers (n = 42) investigated the effect of vitamin D3 supplementation [3000 IU (75 µg) daily for 12 weeks, via an oral spray solution] on VO2 max which was the primary outcome measure. Secondary outcomes included skeletal muscle and lung function.RESULTS:Supplementation significantly increased total 25-hydroxyvitamin D concentrations compared to the placebo group (mean ± SD change from baseline, 36.31 ± 32.34 vs. 6.11 ± 23.93 nmol/L, respectively; P = 0.006). At baseline, 50 and 22 {\%} of footballers presented with vitamin D insufficiency (31-49 nmol/L) and deficiency (",
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T1 - Vitamin D3 supplementation using an oral spray solution resolves deficiency but has no effect on VO2 max in Gaelic footballers: results from a randomised, double-blind, placebo-controlled trial

AU - Todd, Joshua J.

AU - McSorley, Emeir M

AU - Pourshahidi, L. Kirsty

AU - Madigan, Sharon M.

AU - Laird, Eamon

AU - Healy, Martin

AU - Magee, Pamela

PY - 2017/6

Y1 - 2017/6

N2 - PURPOSE:Vitamin D inadequacy is a global health concern in athletes as well as the general population. Whilst the role of vitamin D in skeletal health is well defined, there remains uncertainty over whether vitamin D supplementation has an added benefit beyond bone health.METHODS:This randomised placebo-controlled trial in healthy male and female Gaelic footballers (n = 42) investigated the effect of vitamin D3 supplementation [3000 IU (75 µg) daily for 12 weeks, via an oral spray solution] on VO2 max which was the primary outcome measure. Secondary outcomes included skeletal muscle and lung function.RESULTS:Supplementation significantly increased total 25-hydroxyvitamin D concentrations compared to the placebo group (mean ± SD change from baseline, 36.31 ± 32.34 vs. 6.11 ± 23.93 nmol/L, respectively; P = 0.006). At baseline, 50 and 22 % of footballers presented with vitamin D insufficiency (31-49 nmol/L) and deficiency (

AB - PURPOSE:Vitamin D inadequacy is a global health concern in athletes as well as the general population. Whilst the role of vitamin D in skeletal health is well defined, there remains uncertainty over whether vitamin D supplementation has an added benefit beyond bone health.METHODS:This randomised placebo-controlled trial in healthy male and female Gaelic footballers (n = 42) investigated the effect of vitamin D3 supplementation [3000 IU (75 µg) daily for 12 weeks, via an oral spray solution] on VO2 max which was the primary outcome measure. Secondary outcomes included skeletal muscle and lung function.RESULTS:Supplementation significantly increased total 25-hydroxyvitamin D concentrations compared to the placebo group (mean ± SD change from baseline, 36.31 ± 32.34 vs. 6.11 ± 23.93 nmol/L, respectively; P = 0.006). At baseline, 50 and 22 % of footballers presented with vitamin D insufficiency (31-49 nmol/L) and deficiency (

KW - Athletes

KW - Football

KW - Randomised controlled trial

KW - VO2 max

KW - Vitamin D

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VL - 56

SP - 1577

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JO - European Journal of Nutrition

T2 - European Journal of Nutrition

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