Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 % and 36 % were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 % and 17 % had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 % and 55 % of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.
Hill, T. R., Cotter, A. A., Mitchell, S., Boreham, C. A., Dubitzky, W., Murray, L., Strain, JJ., Flynn, A., Robson, P. J., Wallace, J., Kiely, M., & Cashman, K. D. (2008). Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. BRITISH JOURNAL OF NUTRITION, 99(5), 1061-1067. https://doi.org/10.1017/S0007114507842826