Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort

Tom R. Hill, Alice A. Cotter, Sarah Mitchell, Colin A. Boreham, W Dubitzky, Liam Murray, JJ Strain, Albert Flynn, Paula J. Robson, Julie Wallace, Mairead Kiely, Kevin D. Cashman

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    Abstract

    Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 % and 36 % were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 % and 17 % had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 % and 55 % of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.
    LanguageEnglish
    Pages1061-1067
    JournalBRITISH JOURNAL OF NUTRITION
    Volume99
    Issue number5
    DOIs
    Publication statusPublished - May 2008

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    Northern Ireland
    Vitamin D
    Vitamin D Deficiency
    Serum
    Immunoenzyme Techniques
    Age Groups
    Cross-Sectional Studies

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    Hill, T. R., Cotter, A. A., Mitchell, S., Boreham, C. A., Dubitzky, W., Murray, L., ... Cashman, K. D. (2008). Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. BRITISH JOURNAL OF NUTRITION, 99(5), 1061-1067. https://doi.org/10.1017/S0007114507842826
    Hill, Tom R. ; Cotter, Alice A. ; Mitchell, Sarah ; Boreham, Colin A. ; Dubitzky, W ; Murray, Liam ; Strain, JJ ; Flynn, Albert ; Robson, Paula J. ; Wallace, Julie ; Kiely, Mairead ; Cashman, Kevin D. / Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. In: BRITISH JOURNAL OF NUTRITION. 2008 ; Vol. 99, No. 5. pp. 1061-1067.
    @article{4061e9ca09f848c992d0ac3e4729dcc1,
    title = "Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort",
    abstract = "Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 {\%} and 36 {\%} were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 {\%} and 17 {\%} had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 {\%} and 55 {\%} of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.",
    author = "Hill, {Tom R.} and Cotter, {Alice A.} and Sarah Mitchell and Boreham, {Colin A.} and W Dubitzky and Liam Murray and JJ Strain and Albert Flynn and Robson, {Paula J.} and Julie Wallace and Mairead Kiely and Cashman, {Kevin D.}",
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    Hill, TR, Cotter, AA, Mitchell, S, Boreham, CA, Dubitzky, W, Murray, L, Strain, JJ, Flynn, A, Robson, PJ, Wallace, J, Kiely, M & Cashman, KD 2008, 'Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort', BRITISH JOURNAL OF NUTRITION, vol. 99, no. 5, pp. 1061-1067. https://doi.org/10.1017/S0007114507842826

    Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. / Hill, Tom R.; Cotter, Alice A.; Mitchell, Sarah; Boreham, Colin A.; Dubitzky, W; Murray, Liam; Strain, JJ; Flynn, Albert; Robson, Paula J.; Wallace, Julie; Kiely, Mairead; Cashman, Kevin D.

    In: BRITISH JOURNAL OF NUTRITION, Vol. 99, No. 5, 05.2008, p. 1061-1067.

    Research output: Contribution to journalArticle

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    T1 - Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort

    AU - Hill, Tom R.

    AU - Cotter, Alice A.

    AU - Mitchell, Sarah

    AU - Boreham, Colin A.

    AU - Dubitzky, W

    AU - Murray, Liam

    AU - Strain, JJ

    AU - Flynn, Albert

    AU - Robson, Paula J.

    AU - Wallace, Julie

    AU - Kiely, Mairead

    AU - Cashman, Kevin D.

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    N2 - Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 % and 36 % were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 % and 17 % had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 % and 55 % of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.

    AB - Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 % and 36 % were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 % and 17 % had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 % and 55 % of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.

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