Abstract
| Language | English |
|---|---|
| Title of host publication | Unknown Host Publication |
| Pages | 2223-2301 |
| Volume | 49 |
| Publication status | Published - 2008 |
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Visual function, age-related maculopathy stage and the subsequent development of age-related macular degeneration. / Beirne, Raymond; Hogg, Ruth; Stevenson, Michael; Anderson, Roger; Chakravarthy, Usha.
Unknown Host Publication. Vol. 49 2008. p. 2223-2301.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Visual function, age-related maculopathy stage and the subsequent development of age-related macular degeneration.
AU - Beirne, Raymond
AU - Hogg, Ruth
AU - Stevenson, Michael
AU - Anderson, Roger
AU - Chakravarthy, Usha
PY - 2008
Y1 - 2008
N2 - Purpose: To investigate the relationship between baseline psychophysical measures ofvisual function in age-related maculopathy (ARM) and the subsequent development ofadvanced visual loss from age-related macular degeneration.Methods: 36 participants (aged 52-85yrs) with early ARM and good acuity (≤ 0.3 logMAR) inthe study eye and advanced AMD in the fellow eye underwent a battery of psychophysicaltests at baseline examination (logMAR acuity, Pelli-Robson contrast sensitivity, photopicand scotopic interferometric acuity, achromatic and short-wavelength-sensitive (SWS)resolution acuity). Stereoscopic colour fundus photographs were graded using theWisconsin Age-Related Maculopathy Grading System (WARMGS) and features of ARMwere combined to assign a severity stage from 0 to 5 using the methods described bythe Rotterdam Eye Study. Participants clinical records were examined for a period ofup to 5 years from baseline, with participants being divided into two groups based onwhether or not the study eye lost a significant amount of visual acuity (greater than 3lines of logMAR acuity) in this follow-up period.Results: 8 participants suffered a significant drop in visual acuity during follow-up, while26 participants did not. There was no significant difference in age (M=73.4 vs 71.9yrs;p=0.63) or follow-up time (M=34.2 vs 28.5mths; p=0.34) between these two groups.Achromatic and SWS resolution acuity were both significantly reduced at baseline inthose subjects who developed a significant loss in visual acuity compared to those whodid not (p
AB - Purpose: To investigate the relationship between baseline psychophysical measures ofvisual function in age-related maculopathy (ARM) and the subsequent development ofadvanced visual loss from age-related macular degeneration.Methods: 36 participants (aged 52-85yrs) with early ARM and good acuity (≤ 0.3 logMAR) inthe study eye and advanced AMD in the fellow eye underwent a battery of psychophysicaltests at baseline examination (logMAR acuity, Pelli-Robson contrast sensitivity, photopicand scotopic interferometric acuity, achromatic and short-wavelength-sensitive (SWS)resolution acuity). Stereoscopic colour fundus photographs were graded using theWisconsin Age-Related Maculopathy Grading System (WARMGS) and features of ARMwere combined to assign a severity stage from 0 to 5 using the methods described bythe Rotterdam Eye Study. Participants clinical records were examined for a period ofup to 5 years from baseline, with participants being divided into two groups based onwhether or not the study eye lost a significant amount of visual acuity (greater than 3lines of logMAR acuity) in this follow-up period.Results: 8 participants suffered a significant drop in visual acuity during follow-up, while26 participants did not. There was no significant difference in age (M=73.4 vs 71.9yrs;p=0.63) or follow-up time (M=34.2 vs 28.5mths; p=0.34) between these two groups.Achromatic and SWS resolution acuity were both significantly reduced at baseline inthose subjects who developed a significant loss in visual acuity compared to those whodid not (p
M3 - Conference contribution
VL - 49
SP - 2223
EP - 2301
BT - Unknown Host Publication
ER -