TY - JOUR
T1 - Vertical graphene nanoflakes for the immobilization, electrocatalytic oxidation andquantitative detection of DNA
AU - Shang, N
AU - Kumar, A
AU - Sun, N
AU - Sharma, S
AU - Papakonstantinou, P
AU - Li, MX
AU - Blackley, RA
AU - Zhou, W
AU - Kalrsson, LS
AU - Silva, SRP
PY - 2012/10/1
Y1 - 2012/10/1
N2 - Vertical graphene nanoflake integrated films having a high density of edge planes have been used as an electrochemical platform to systematically investigate the immobilization, electrochemical oxidation kinetics and direct quantitative determination of native DNA. Consistently, both transmission electron microscopy and atomic force microscopy observations demonstrate the presence of a self-assembled monolayer of nativeDNA, immobilized on the graphene nanoflakes. Graphene shows excellent electrocatalytic activity for the electrooxidation of double stranded DNA, better than carbon nanotubes and glassy carbon, due to the abundance of electrocatalytic graphene edges present not only at the top but also along the sides of each graphene nanoflake.
AB - Vertical graphene nanoflake integrated films having a high density of edge planes have been used as an electrochemical platform to systematically investigate the immobilization, electrochemical oxidation kinetics and direct quantitative determination of native DNA. Consistently, both transmission electron microscopy and atomic force microscopy observations demonstrate the presence of a self-assembled monolayer of nativeDNA, immobilized on the graphene nanoflakes. Graphene shows excellent electrocatalytic activity for the electrooxidation of double stranded DNA, better than carbon nanotubes and glassy carbon, due to the abundance of electrocatalytic graphene edges present not only at the top but also along the sides of each graphene nanoflake.
U2 - 10.1016/j.elecom.2012.09.036
DO - 10.1016/j.elecom.2012.09.036
M3 - Article
SN - 1388-2481
VL - 25
SP - 140
EP - 143
JO - Electrochemistry Communications
JF - Electrochemistry Communications
ER -