UK clinical guideline for the prevention and treatment of osteoporosis

Celia L Gregson, David J Armstrong, Jean Bowden, Cyrus Cooper, John Edwards, Neil J L Gittoes, Nicholas Harvey, John Kanis, Sarah Leyland, Rebecca Low, Eugene McCloskey, Katie Moss, Jane Parker, Zoe Paskins, Kenneth Poole, David M Reid, Mike Stone, Julia Thomson, Nic Vine, Juliet Compston

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    The National Osteoporosis Guideline Group (NOGG) has revised the UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older. Accredited by NICE, this guideline is relevant for all healthcare professionals involved in osteoporosis management.IntroductionThe UK National Osteoporosis Guideline Group (NOGG) first produced a guideline on the prevention and treatment of osteoporosis in 2008, with updates in 2013 and 2017. This paper presents a major update of the guideline, the scope of which is to review the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older.MethodsWhere available, systematic reviews, meta-analyses and randomised controlled trials were used to provide the evidence base. Conclusions and recommendations were systematically graded according to the strength of the available evidence.ResultsReview of the evidence and recommendations are provided for the diagnosis of osteoporosis, fracture-risk assessment and intervention thresholds, management of vertebral fractures, non-pharmacological and pharmacological treatments, including duration and monitoring of anti-resorptive therapy, glucocorticoid-induced osteoporosis, and models of care for fracture prevention. Recommendations are made for training; service leads and commissioners of healthcare; and for review criteria for audit and quality improvement.ConclusionThe guideline, which has received accreditation from the National Institute of Health and Care Excellence (NICE), provides a comprehensive overview of the assessment and management of osteoporosis for all healthcare professionals involved in its management. This position paper has been endorsed by the International Osteoporosis Foundation and by the European Society for the Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
    Original languageEnglish
    Pages (from-to)1-46
    Number of pages46
    JournalArchives of osteoporosis
    Volume17
    Issue number1
    Early online date1 Apr 2022
    DOIs
    Publication statusE-pub ahead of print - 1 Apr 2022

    Keywords

    • Osteoporosis
    • Fracture
    • Guideline
    • Nogg
    • Humans
    • Risk Assessment
    • Bone Density
    • Middle Aged
    • Female
    • Male
    • Fractures, Bone
    • United Kingdom

    Fingerprint

    Dive into the research topics of 'UK clinical guideline for the prevention and treatment of osteoporosis'. Together they form a unique fingerprint.

    Cite this