Type 1 Diabetes Is a Barrier to Obesity Treatment: Patient Insights From a Mixed-Methods Study

  • Ebaa Al Ozairi
  • , Dalal Alsaeed
  • , Alvin Mondoh
  • , Etab Taghadom
  • , Mohammad Irshad
  • , Dherar Alroudhan
  • , Jumana Al Kandari
  • , Werd Al-Najim
  • , Carel W le Roux

Research output: Contribution to journalArticlepeer-review

Abstract

Background
Globally, many patients with Type 1 diabetes (T1D) are now characterized by excess adipose tissue and features of insulin resistance. In Kuwait, rapid urbanization, shifts in dietary patterns, and decreased physical activity have contributed to rising obesity prevalence in the general population.

Objectives
We aimed to investigate the interplay between the diseases of obesity and T1D, examining patients' perspectives on why they gained body weight, psychological aspects, and management challenges.

Methods
A mixed-methods approach was employed, encompassing quantitative analysis of body mass index (BMI) and lifestyle factors among 51 participants with T1D and obesity or obesity-related complications and a thematic analysis of perceptions and experiences related to obesity and T1D using an online survey.

Results
Participants identified lifestyle factors as the primary contributors to obesity, emphasizing the need for holistic interventions. About 56.8% of the participants perceived T1D as a barrier to obesity treatment. The qualitative analysis revealed four themes: 1) negative perceptions about obesity, 2) poor interface with healthcare professionals (HCPs), 3) lack of suggestions for improving obesity management, and 4) poor self-image and awareness. This provided in-depth insights into participants' perceptions, worries, experiences, and suggestions for managing obesity in the context of T1D.

Conclusions
This study contributes a nuanced understanding of obesity in patients with T1D, shedding light on the complexities beyond glycemic control. The findings emphasize the need for patient-centered, multidisciplinary approaches that consider both medical and psychological aspects in the management of obesity within patients with T1D.
Original languageEnglish
Article number1461796
Pages (from-to)1-11
Number of pages11
JournalJournal of Obesity
Volume2025
Early online date14 Dec 2025
DOIs
Publication statusPublished (in print/issue) - 14 Dec 2025

Bibliographical note

Publisher Copyright:
Copyright © 2025 Ebaa Al Ozairi et al. Journal of Obesity published by John Wiley & Sons Ltd.

Data Access Statement

The data that support the findings of this study are available upon request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

Funding

SOPHIA has received funding from the Innovative Medicines 2 Joint Undertaking under grant agreement No.875534. Tis Joint Undertaking received support from the European Union’s Horizon 2020 research and innovation program and EFPIA and T1D Exchange, JDRF, and Obesity Action Coalition

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Obesity
  • T1d
  • Body Weight Perceptions
  • Humans
  • Diabetes Mellitus, Type 1
  • Body Mass Index
  • Life Style
  • Adult
  • Middle Aged
  • Kuwait
  • Female
  • Male
  • Young Adult
  • Surveys and Questionnaires
  • T1D
  • body weight perceptions
  • obesity
  • Obesity/therapy
  • Diabetes Mellitus, Type 1/complications
  • Kuwait/epidemiology
  • Diabetes Mellitus, Type 1 - complications - psychology
  • Kuwait - epidemiology
  • Obesity - therapy - psychology - complications - epidemiology

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