Transcription factors of Interleukin-1&beta; (IL-1&beta;) are important for enhancer of Human Immunodeficiency Virus Type 1 Long Terminal Repeat sequence (HIV-1 LTR)

Steven Watterson

doi:10.6084/m9.figshare.776915

Transcription factors of Interleukin-1β (IL-1β) are important for enhancer of Human Immunodeficiency Virus Type 1 Long Terminal Repeat sequence (HIV-1 LTR)

Research output: Non-textual form › Web publication/site

Abstract

There are more than 2,500 specific interactions between Human Immunodeficiency Virus Type 1 (HIV-1) and host cells. HIV-1 long terminal repeat (HIV-1 LTR) is important in viral replication. Interleukin-1β (IL-1β) is a cytokine with a pivotal role in the immune response. Certain pathways of HIV-1 LTR replication and as IL-1β activation are well characterized. We developed an integrated model of the HIV-1 LTR and IL-1β activation. We present this model using the Systems Biology Graphical Notation (SBGN) within the monocyte/macrophage.  

Original language	English
Publisher	figshare
DOIs	https://doi.org/10.6084/m9.figshare.776915
Publication status	Published (in print/issue) - 21 Aug 2013

Keywords

sbgn
hiv1
il1b

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.6084/m9.figshare.776915

http://files.figshare.com/1175619/HIV1_IL1b.pdf

Cite this

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abstract = "There are more than 2,500 specific interactions between Human Immunodeficiency Virus Type 1 (HIV-1) and host cells. HIV-1 long terminal repeat (HIV-1 LTR) is important in viral replication. Interleukin-1β (IL-1β) is a cytokine with a pivotal role in the immune response. Certain pathways of HIV-1 LTR replication and as IL-1β activation are well characterized. We developed an integrated model of the HIV-1 LTR and IL-1β activation. We present this model using the Systems Biology Graphical Notation (SBGN) within the monocyte/macrophage. ",

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AB - There are more than 2,500 specific interactions between Human Immunodeficiency Virus Type 1 (HIV-1) and host cells. HIV-1 long terminal repeat (HIV-1 LTR) is important in viral replication. Interleukin-1β (IL-1β) is a cytokine with a pivotal role in the immune response. Certain pathways of HIV-1 LTR replication and as IL-1β activation are well characterized. We developed an integrated model of the HIV-1 LTR and IL-1β activation. We present this model using the Systems Biology Graphical Notation (SBGN) within the monocyte/macrophage.

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