Total radical trapping antioxidant potential (TRAP) and exercise

PC Sharpe, EB Duly, D MacAuley, Evie Gardner, C Mulholland, G Stott, CAG Boreham, G Kennedy, AE Evans, TR Trinick

    Research output: Contribution to journalArticle

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    Abstract

    The relationship between physical activity, physical fitness and total radical trapping antioxidant potential (TRAP) was examined in the Northern Ireland Health and Activity Survey. This was a cross-sectional population study (n = 1600) using a two-stage probability sample of the population. TRAP was calculated using the sum of the individual serum antioxidant concentrations (urate, protein thiols, ascorbate, a tocopherol and bilirubin) multiplied by their respective stoichiometric values. Physical fitness was determined by estimation of VO(2)max by extrapolation from submaximal oxygen uptake, and physical activity was recorded by computer-assisted interview. Mean serum TRAP concentrations were significantly higher in males (653 +/- 8.2 mu mol/l, mean +/- SEM) compared to females (564 +/- 8.0 mu mol/l) (p < 0.0001). Both male and female smokers had significantly lower TRAP values than non-smokers (males p < 0.0001, females p = 0.02). In females, there was a positive relationship of TRAP with age (p < 0.001) and body mass index (p < 0.001) but a negative relationship with physical fitness (p < 0.05). The known beneficial effects of exercise and activity do not appear to be directly mediated through increased antioxidant status.
    LanguageEnglish
    Pages223-228
    JournalQJM - Monthly Journal of the Association of Physicians
    Volume89
    Issue number3
    Publication statusPublished - Mar 1996

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    Antioxidants
    Physical Fitness
    Northern Ireland
    Sampling Studies
    Tocopherols
    Health Surveys
    Uric Acid
    Serum
    Bilirubin
    Sulfhydryl Compounds
    Population
    Body Mass Index
    Cross-Sectional Studies
    Interviews
    Oxygen
    Proteins

    Cite this

    Sharpe, PC., Duly, EB., MacAuley, D., Gardner, E., Mulholland, C., Stott, G., ... Trinick, TR. (1996). Total radical trapping antioxidant potential (TRAP) and exercise. QJM - Monthly Journal of the Association of Physicians, 89(3), 223-228.
    Sharpe, PC ; Duly, EB ; MacAuley, D ; Gardner, Evie ; Mulholland, C ; Stott, G ; Boreham, CAG ; Kennedy, G ; Evans, AE ; Trinick, TR. / Total radical trapping antioxidant potential (TRAP) and exercise. In: QJM - Monthly Journal of the Association of Physicians. 1996 ; Vol. 89, No. 3. pp. 223-228.
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    abstract = "The relationship between physical activity, physical fitness and total radical trapping antioxidant potential (TRAP) was examined in the Northern Ireland Health and Activity Survey. This was a cross-sectional population study (n = 1600) using a two-stage probability sample of the population. TRAP was calculated using the sum of the individual serum antioxidant concentrations (urate, protein thiols, ascorbate, a tocopherol and bilirubin) multiplied by their respective stoichiometric values. Physical fitness was determined by estimation of VO(2)max by extrapolation from submaximal oxygen uptake, and physical activity was recorded by computer-assisted interview. Mean serum TRAP concentrations were significantly higher in males (653 +/- 8.2 mu mol/l, mean +/- SEM) compared to females (564 +/- 8.0 mu mol/l) (p < 0.0001). Both male and female smokers had significantly lower TRAP values than non-smokers (males p < 0.0001, females p = 0.02). In females, there was a positive relationship of TRAP with age (p < 0.001) and body mass index (p < 0.001) but a negative relationship with physical fitness (p < 0.05). The known beneficial effects of exercise and activity do not appear to be directly mediated through increased antioxidant status.",
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    Sharpe, PC, Duly, EB, MacAuley, D, Gardner, E, Mulholland, C, Stott, G, Boreham, CAG, Kennedy, G, Evans, AE & Trinick, TR 1996, 'Total radical trapping antioxidant potential (TRAP) and exercise', QJM - Monthly Journal of the Association of Physicians, vol. 89, no. 3, pp. 223-228.

    Total radical trapping antioxidant potential (TRAP) and exercise. / Sharpe, PC; Duly, EB; MacAuley, D; Gardner, Evie; Mulholland, C; Stott, G; Boreham, CAG; Kennedy, G; Evans, AE; Trinick, TR.

    In: QJM - Monthly Journal of the Association of Physicians, Vol. 89, No. 3, 03.1996, p. 223-228.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Total radical trapping antioxidant potential (TRAP) and exercise

    AU - Sharpe, PC

    AU - Duly, EB

    AU - MacAuley, D

    AU - Gardner, Evie

    AU - Mulholland, C

    AU - Stott, G

    AU - Boreham, CAG

    AU - Kennedy, G

    AU - Evans, AE

    AU - Trinick, TR

    PY - 1996/3

    Y1 - 1996/3

    N2 - The relationship between physical activity, physical fitness and total radical trapping antioxidant potential (TRAP) was examined in the Northern Ireland Health and Activity Survey. This was a cross-sectional population study (n = 1600) using a two-stage probability sample of the population. TRAP was calculated using the sum of the individual serum antioxidant concentrations (urate, protein thiols, ascorbate, a tocopherol and bilirubin) multiplied by their respective stoichiometric values. Physical fitness was determined by estimation of VO(2)max by extrapolation from submaximal oxygen uptake, and physical activity was recorded by computer-assisted interview. Mean serum TRAP concentrations were significantly higher in males (653 +/- 8.2 mu mol/l, mean +/- SEM) compared to females (564 +/- 8.0 mu mol/l) (p < 0.0001). Both male and female smokers had significantly lower TRAP values than non-smokers (males p < 0.0001, females p = 0.02). In females, there was a positive relationship of TRAP with age (p < 0.001) and body mass index (p < 0.001) but a negative relationship with physical fitness (p < 0.05). The known beneficial effects of exercise and activity do not appear to be directly mediated through increased antioxidant status.

    AB - The relationship between physical activity, physical fitness and total radical trapping antioxidant potential (TRAP) was examined in the Northern Ireland Health and Activity Survey. This was a cross-sectional population study (n = 1600) using a two-stage probability sample of the population. TRAP was calculated using the sum of the individual serum antioxidant concentrations (urate, protein thiols, ascorbate, a tocopherol and bilirubin) multiplied by their respective stoichiometric values. Physical fitness was determined by estimation of VO(2)max by extrapolation from submaximal oxygen uptake, and physical activity was recorded by computer-assisted interview. Mean serum TRAP concentrations were significantly higher in males (653 +/- 8.2 mu mol/l, mean +/- SEM) compared to females (564 +/- 8.0 mu mol/l) (p < 0.0001). Both male and female smokers had significantly lower TRAP values than non-smokers (males p < 0.0001, females p = 0.02). In females, there was a positive relationship of TRAP with age (p < 0.001) and body mass index (p < 0.001) but a negative relationship with physical fitness (p < 0.05). The known beneficial effects of exercise and activity do not appear to be directly mediated through increased antioxidant status.

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    EP - 228

    JO - QJM: An International Journal of Medicine

    T2 - QJM: An International Journal of Medicine

    JF - QJM: An International Journal of Medicine

    SN - 1460-2725

    IS - 3

    ER -

    Sharpe PC, Duly EB, MacAuley D, Gardner E, Mulholland C, Stott G et al. Total radical trapping antioxidant potential (TRAP) and exercise. QJM - Monthly Journal of the Association of Physicians. 1996 Mar;89(3):223-228.