The Use of Pressure and Silicone in Hypertrophic Scar Management in Burns Patients: A Pilot Randomized Controlled Trial

Daniel Harte, Jude Gordon, Maxine Shaw, May Stinson, Alison Porter-Armstrong

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

This pilot study investigates whether pressure and silicone therapy used simultaneously are more effective in treating multiple characteristics of hypertrophic scars than pressure alone. A pilot randomized controlled trial was conducted. Twenty-two participants with hypertrophic burn scars were randomized to receive Jobskin pressure garments and Mepiforin silicone sheeting or Jobskin pressure garments alone. The Vancouver Scar Scale (VSS) was used to measure multiple scar characteristics at baseline, week 12, and week 24. No statistically significant difference was found in the rate of change of the VSS scores between the pressure therapy (PT) group and the pressure therapy and silicone group at week 12 or week 24; however, die mean scores of both groups reduced over 24 weeks. There were no statistically significant changes in the VSS subscores (scar height, vascularity, pliability, mid pigmentation) from baseline to week 12 or week 24. A statistically significant relationship was observed between the VSS score and TBSA burned (<30%) in the PT group at baseline (P < .05), over 12 weeks (P < .05), and over 24 weeks (P < .05). Given the limitations of this study, especially the small sample size, further research is necessary before any firm conclusions can be drawn on this therapy approach. However, this pilot study has discussed the recurring issues in the research regarding these controversial treatments and has yielded potential for further investigation in a fully powered randomized controlled trial. (J Burn Care Res 2009;30:632-642)
LanguageEnglish
Pages632-642
JournalJournal of Burn Care and Research
Volume30
Issue number4
DOIs
Publication statusPublished - 8 Jul 2009

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Hypertrophic Cicatrix
Silicones
Burns
Randomized Controlled Trials
Cicatrix
Pressure
Group Psychotherapy
Clothing
Pigmentation
Research
Sample Size
Pliability
Therapeutics

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title = "The Use of Pressure and Silicone in Hypertrophic Scar Management in Burns Patients: A Pilot Randomized Controlled Trial",
abstract = "This pilot study investigates whether pressure and silicone therapy used simultaneously are more effective in treating multiple characteristics of hypertrophic scars than pressure alone. A pilot randomized controlled trial was conducted. Twenty-two participants with hypertrophic burn scars were randomized to receive Jobskin pressure garments and Mepiforin silicone sheeting or Jobskin pressure garments alone. The Vancouver Scar Scale (VSS) was used to measure multiple scar characteristics at baseline, week 12, and week 24. No statistically significant difference was found in the rate of change of the VSS scores between the pressure therapy (PT) group and the pressure therapy and silicone group at week 12 or week 24; however, die mean scores of both groups reduced over 24 weeks. There were no statistically significant changes in the VSS subscores (scar height, vascularity, pliability, mid pigmentation) from baseline to week 12 or week 24. A statistically significant relationship was observed between the VSS score and TBSA burned (<30{\%}) in the PT group at baseline (P < .05), over 12 weeks (P < .05), and over 24 weeks (P < .05). Given the limitations of this study, especially the small sample size, further research is necessary before any firm conclusions can be drawn on this therapy approach. However, this pilot study has discussed the recurring issues in the research regarding these controversial treatments and has yielded potential for further investigation in a fully powered randomized controlled trial. (J Burn Care Res 2009;30:632-642)",
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The Use of Pressure and Silicone in Hypertrophic Scar Management in Burns Patients: A Pilot Randomized Controlled Trial. / Harte, Daniel; Gordon, Jude; Shaw, Maxine; Stinson, May; Porter-Armstrong, Alison.

In: Journal of Burn Care and Research, Vol. 30, No. 4, 08.07.2009, p. 632-642.

Research output: Contribution to journalArticle

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