The use of electrospray mass spectrometry in the detection and determination of molecules of biological significance

Franklin Smyth

The use of electrospray mass spectrometry in the detection and determination of molecules of biological significance

Franklin Smyth

Research output: Contribution to journal › Article

Abstract

This review will briefly explain the mechanism of electrospray ionisation, discuss the molecules and species that can be ionised by this technique such as proteins, nucleotides, carbohydrates, drugs, pollutants, organometallic and inorganic species. It will also select relevant examples from the recent literature that illustrate the wide applicability of electrospray mass spectrometry when interfaced to HPLC and CE for the detection and determination of such biologically significant molecules, (C) 1999 Elsevier Science B.V. All rights reserved.

Original language	English
Pages (from-to)	335-346
Journal	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume	18
Issue number	5
Publication status	Published - May 1999

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Smyth, F. (1999). The use of electrospray mass spectrometry in the detection and determination of molecules of biological significance. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 18(5), 335-346.

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AB - This review will briefly explain the mechanism of electrospray ionisation, discuss the molecules and species that can be ionised by this technique such as proteins, nucleotides, carbohydrates, drugs, pollutants, organometallic and inorganic species. It will also select relevant examples from the recent literature that illustrate the wide applicability of electrospray mass spectrometry when interfaced to HPLC and CE for the detection and determination of such biologically significant molecules, (C) 1999 Elsevier Science B.V. All rights reserved.

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