The relationship between whole-blood serotonin and subjective mood in apparently healthy postmenopausal women

Maresa E Duffy, Barbara J Stewart-Knox, Christopher McConville, Ian Bradbury, JM O'Connor, Anders Helander, JJ Strain

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The aim of this research has been to determine the degree to which biochemical indices of mood reflect subjective mood. Potential relationships between whole-blood (WB) serotonin (5-hydroxytryptamine, 5-HT) levels as determined by the positive and negative affect schedule (PANAS) have been explored in apparently healthy postmenopausal women (n = 39). Partial correlations indicated that WB 5-HT was positively associated with positive affect (p = 0.03). No association was apparent for negative affect. These findings indicate that WB 5-HT and positive affect are related in postmenopausal women. (c) 2006 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)165-168
JournalBiological Psychology
Issue number2
Publication statusPublished - Aug 2006


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