The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

Nichola McCullough, Helen Dolk, Maria Loane, Briege M Lagan, Casey Frank, Brian Craig

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Background
The Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.


Methods
We performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.


Findings
Refusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.


Conclusions
Our results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.
LanguageEnglish
Title of host publicationInternational Conference for Administrative Data Research
EditorsMark Elliot
Volume3
Edition2
Publication statusPublished - 14 Jun 2018
EventConference Proceedings for International Conference for Administrative Data Research - Queens University, Belfast, Northern Ireland, Belfast, Northern Ireland
Duration: 21 Jun 201822 Jun 2018
Conference number: 3rd
https://ijpds.org/issue/view/8

Publication series

NameInternational Journal of Population Data Science
PublisherSwansea University
ISSN (Print)2399-4908

Conference

ConferenceConference Proceedings for International Conference for Administrative Data Research
CountryNorthern Ireland
CityBelfast
Period21/06/1822/06/18
Internet address

Fingerprint

Northern Ireland
Information Storage and Retrieval
Case-Control Studies
Self Report
Prescriptions
Medical Record Linkage
Pregnancy
Congenital Heart Defects
Health Behavior
First Pregnancy Trimester
Folic Acid
Pregnant Women
Smoking
Surveys and Questionnaires
Population

Cite this

McCullough, N., Dolk, H., Loane, M., Lagan, B. M., Frank, C., & Craig, B. (2018). The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. In M. Elliot (Ed.), International Conference for Administrative Data Research (2 ed., Vol. 3). (International Journal of Population Data Science).
McCullough, Nichola ; Dolk, Helen ; Loane, Maria ; Lagan, Briege M ; Frank, Casey ; Craig, Brian . / The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. International Conference for Administrative Data Research. editor / Mark Elliot. Vol. 3 2. ed. 2018. (International Journal of Population Data Science).
@inproceedings{85f647e4b80445cabb6f71d3eaa5682c,
title = "The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method",
abstract = "BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8{\%}). Among those recruited, consent for access and linkage to medical records was high (98{\%}). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.",
author = "Nichola McCullough and Helen Dolk and Maria Loane and Lagan, {Briege M} and Casey Frank and Brian Craig",
year = "2018",
month = "6",
day = "14",
language = "English",
volume = "3",
series = "International Journal of Population Data Science",
publisher = "Swansea University",
editor = "Elliot, {Mark }",
booktitle = "International Conference for Administrative Data Research",
edition = "2",

}

McCullough, N, Dolk, H, Loane, M, Lagan, BM, Frank, C & Craig, B 2018, The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. in M Elliot (ed.), International Conference for Administrative Data Research. 2 edn, vol. 3, International Journal of Population Data Science, Conference Proceedings for International Conference for Administrative Data Research, Belfast, Northern Ireland, 21/06/18.

The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. / McCullough, Nichola; Dolk, Helen; Loane, Maria; Lagan, Briege M; Frank, Casey; Craig, Brian .

International Conference for Administrative Data Research. ed. / Mark Elliot. Vol. 3 2. ed. 2018. (International Journal of Population Data Science).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

AU - McCullough, Nichola

AU - Dolk, Helen

AU - Loane, Maria

AU - Lagan, Briege M

AU - Frank, Casey

AU - Craig, Brian

PY - 2018/6/14

Y1 - 2018/6/14

N2 - BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.

AB - BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.

M3 - Conference contribution

VL - 3

T3 - International Journal of Population Data Science

BT - International Conference for Administrative Data Research

A2 - Elliot, Mark

ER -

McCullough N, Dolk H, Loane M, Lagan BM, Frank C, Craig B. The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. In Elliot M, editor, International Conference for Administrative Data Research. 2 ed. Vol. 3. 2018. (International Journal of Population Data Science).