The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

Nichola McCullough; Helen Dolk; Maria Loane; Briege M Lagan; Frank Casey; Brian  Craig

The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

Nichola McCullough, Helen Dolk, Maria Loane, Briege M Lagan, Frank Casey, Brian Craig

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Abstract

Background
The Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.

Methods
We performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.

Findings
Refusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.

Conclusions
Our results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.

Original language	English
Title of host publication	International Conference for Administrative Data Research
Editors	Mark Elliot
Volume	3
Edition	2
Publication status	Published (in print/issue) - 14 Jun 2018
Event	Conference Proceedings for International Conference for Administrative Data Research - Queens University, Belfast, Northern Ireland, Belfast, Northern Ireland Duration: 21 Jun 2018 → 22 Jun 2018 Conference number: 3rd https://ijpds.org/issue/view/8

Publication series

Name	International Journal of Population Data Science
Publisher	Swansea University
ISSN (Print)	2399-4908

Conference

Conference	Conference Proceedings for International Conference for Administrative Data Research
Country/Territory	Northern Ireland
City	Belfast
Period	21/06/18 → 22/06/18
Internet address	https://ijpds.org/issue/view/8

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

2018 McCullough, Dolk, Loane, Lagan et al. The Northern Ireland Baby Hearts Study A Case-Control study using a hybrid data linkage method. International Journal of Population Data Conf PaperFinal published version, 205 KBLicence: CC BY-NC-ND

https://doi.org/10.23889/ijpds.v3i2.549Licence: Unspecified

1 Article

Risk Factors for Congenital Heart Disease: the Baby Hearts Study, a population-based case-control study
Dolk, H., McCullough, N., Callaghan, S., Casey, F., Craig, B., Given, J., Loane, M., Lagan, B., Bunting, B., Boyle, B. & Dabir, T., 24 Feb 2020, In: PLoS ONE. 15, 2, p. 1-22 22 p., e0227908.
Research output: Contribution to journal › Article › peer-review

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Cite this

@inproceedings{85f647e4b80445cabb6f71d3eaa5682c,

title = "The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method",

abstract = "BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.",

author = "Nichola McCullough and Helen Dolk and Maria Loane and Lagan, {Briege M} and Frank Casey and Brian Craig",

year = "2018",

month = jun,

day = "14",

language = "English",

volume = "3",

series = "International Journal of Population Data Science",

publisher = "Swansea University",

editor = "Elliot, {Mark }",

booktitle = "International Conference for Administrative Data Research",

edition = "2",

note = "Conference Proceedings for International Conference for Administrative Data Research ; Conference date: 21-06-2018 Through 22-06-2018",

url = "https://ijpds.org/issue/view/8",

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McCullough, N, Dolk, H , Loane, M, Lagan, BM, Casey, F & Craig, B 2018, The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. in M Elliot (ed.), International Conference for Administrative Data Research. 2 edn, vol. 3, International Journal of Population Data Science, Conference Proceedings for International Conference for Administrative Data Research, Belfast, Northern Ireland, 21/06/18. <https://doi.org/10.23889/ijpds.v3i2.549>

The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method. / McCullough, Nichola; Dolk, Helen ; Loane, Maria et al.
International Conference for Administrative Data Research. ed. / Mark Elliot. Vol. 3 2. ed. 2018. (International Journal of Population Data Science).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

AU - McCullough, Nichola

AU - Dolk, Helen

AU - Loane, Maria

AU - Lagan, Briege M

AU - Casey, Frank

AU - Craig, Brian

N1 - Conference code: 3rd

PY - 2018/6/14

Y1 - 2018/6/14

N2 - BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.

AB - BackgroundThe Northern Ireland (NI) Baby Hearts study aimed to investigate risk factors for congenital heart defects (CHD), and to investigate the health behaviours of a representative sample of NI pregnant women.MethodsWe performed a case-control study with hybrid data collection methods, including self-administered iPad questionnaire or postal questionnaire, information held in maternity records and linkage to prescription records. Cases (n=286) were recruited following diagnosis prenatally or postnatally, controls (n=966) were recruited during recruitment months in each maternity unit at 18-20 weeks gestation.FindingsRefusal rates for questionnaire completion were low (7-8%). Among those recruited, consent for access and linkage to medical records was high (98%). Recruitment of both cases and controls was closely representative of the NI population in terms of age, area of residence and deprivation. There was considerable discordance between self-report questionnaires, maternity records and prescription records regarding medications taken in the first trimester, and between self-report questionnaires and maternity records regarding behaviours such as preconceptional folic acid, pregnancy planning, and smoking. However, there were no differences between cases and controls that would indicate recall bias.ConclusionsOur results suggest that hybrid data collection approaches are a useful way forward for aetiological studies.

M3 - Conference contribution

VL - 3

T3 - International Journal of Population Data Science

BT - International Conference for Administrative Data Research

A2 - Elliot, Mark

T2 - Conference Proceedings for International Conference for Administrative Data Research

Y2 - 21 June 2018 through 22 June 2018

ER -

The Northern Ireland Baby Hearts Study: A Case-Control study using a hybrid data linkage method

Abstract

Publication series

Conference

UN SDGs

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Research output

Risk Factors for Congenital Heart Disease: the Baby Hearts Study, a population-based case-control study

Cite this