THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST

F KEE, J WESTON, EE MCCRUM, D MCMASTER, J YARNELL, JC FRUCHART, JM BARD, F CAMBIEN, AE EVANS

    Research output: Contribution to journalArticle

    Abstract

    The objective of the study was to evaluate the contribution of dietary factors to variation of plasma levels of lipids, apoproteins and lipoparticles in the Northern Ireland population. This study was part of a larger case-control study of the genetic and environmental determinants of myocardial infarction in France and Northern Ireland. A random sample of 175 middle aged men was drawn from the population covered by the Belfast MONICA project register. Habitual diet was assessed by a questionnaire. A blood sample was obtained after an over-night fast for determination of plasma levels of lipids, apoproteins and lipoparticles. All participants had a medical examination and completed a lifestyle questionnaire. In a stepwise regression, after adjusting for co-factors (i) vitamin C and (ii) alcohol consumption were the only nutrients which contributed significantly to the variation in, respectively, (i) Total Cholesterol, LDL Cholesterol and Apolipoprotein B (inverse correlation) and (ii) HDL Cholesterol and LpAI (positive correlation). The amount of variation explained by the final models was modest, ranging from 4% to 15%. In conclusion, in this Northern Ireland population, habitual diet contributes to little of the variation in plasma levels of lipids, apoproteins and lipoparticles.
    LanguageEnglish
    Pages18-25
    JournalEpidemiology and Public Health
    Volume43
    Issue number1
    Publication statusPublished - 1995

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    Northern Ireland
    Apoproteins
    Diet
    Lipids
    Population
    Apolipoproteins B
    Alcohol Drinking
    LDL Cholesterol
    HDL Cholesterol
    Ascorbic Acid
    France
    Case-Control Studies
    Life Style
    Myocardial Infarction
    Food
    Surveys and Questionnaires

    Cite this

    KEE, F., WESTON, J., MCCRUM, EE., MCMASTER, D., YARNELL, J., FRUCHART, JC., ... EVANS, AE. (1995). THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST. 43(1), 18-25.
    KEE, F ; WESTON, J ; MCCRUM, EE ; MCMASTER, D ; YARNELL, J ; FRUCHART, JC ; BARD, JM ; CAMBIEN, F ; EVANS, AE. / THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST. 1995 ; Vol. 43, No. 1. pp. 18-25.
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    abstract = "The objective of the study was to evaluate the contribution of dietary factors to variation of plasma levels of lipids, apoproteins and lipoparticles in the Northern Ireland population. This study was part of a larger case-control study of the genetic and environmental determinants of myocardial infarction in France and Northern Ireland. A random sample of 175 middle aged men was drawn from the population covered by the Belfast MONICA project register. Habitual diet was assessed by a questionnaire. A blood sample was obtained after an over-night fast for determination of plasma levels of lipids, apoproteins and lipoparticles. All participants had a medical examination and completed a lifestyle questionnaire. In a stepwise regression, after adjusting for co-factors (i) vitamin C and (ii) alcohol consumption were the only nutrients which contributed significantly to the variation in, respectively, (i) Total Cholesterol, LDL Cholesterol and Apolipoprotein B (inverse correlation) and (ii) HDL Cholesterol and LpAI (positive correlation). The amount of variation explained by the final models was modest, ranging from 4{\%} to 15{\%}. In conclusion, in this Northern Ireland population, habitual diet contributes to little of the variation in plasma levels of lipids, apoproteins and lipoparticles.",
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    KEE, F, WESTON, J, MCCRUM, EE, MCMASTER, D, YARNELL, J, FRUCHART, JC, BARD, JM, CAMBIEN, F & EVANS, AE 1995, 'THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST', vol. 43, no. 1, pp. 18-25.

    THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST. / KEE, F; WESTON, J; MCCRUM, EE; MCMASTER, D; YARNELL, J; FRUCHART, JC; BARD, JM; CAMBIEN, F; EVANS, AE.

    Vol. 43, No. 1, 1995, p. 18-25.

    Research output: Contribution to journalArticle

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    AU - WESTON, J

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    AU - MCMASTER, D

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    AU - CAMBIEN, F

    AU - EVANS, AE

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    N2 - The objective of the study was to evaluate the contribution of dietary factors to variation of plasma levels of lipids, apoproteins and lipoparticles in the Northern Ireland population. This study was part of a larger case-control study of the genetic and environmental determinants of myocardial infarction in France and Northern Ireland. A random sample of 175 middle aged men was drawn from the population covered by the Belfast MONICA project register. Habitual diet was assessed by a questionnaire. A blood sample was obtained after an over-night fast for determination of plasma levels of lipids, apoproteins and lipoparticles. All participants had a medical examination and completed a lifestyle questionnaire. In a stepwise regression, after adjusting for co-factors (i) vitamin C and (ii) alcohol consumption were the only nutrients which contributed significantly to the variation in, respectively, (i) Total Cholesterol, LDL Cholesterol and Apolipoprotein B (inverse correlation) and (ii) HDL Cholesterol and LpAI (positive correlation). The amount of variation explained by the final models was modest, ranging from 4% to 15%. In conclusion, in this Northern Ireland population, habitual diet contributes to little of the variation in plasma levels of lipids, apoproteins and lipoparticles.

    AB - The objective of the study was to evaluate the contribution of dietary factors to variation of plasma levels of lipids, apoproteins and lipoparticles in the Northern Ireland population. This study was part of a larger case-control study of the genetic and environmental determinants of myocardial infarction in France and Northern Ireland. A random sample of 175 middle aged men was drawn from the population covered by the Belfast MONICA project register. Habitual diet was assessed by a questionnaire. A blood sample was obtained after an over-night fast for determination of plasma levels of lipids, apoproteins and lipoparticles. All participants had a medical examination and completed a lifestyle questionnaire. In a stepwise regression, after adjusting for co-factors (i) vitamin C and (ii) alcohol consumption were the only nutrients which contributed significantly to the variation in, respectively, (i) Total Cholesterol, LDL Cholesterol and Apolipoprotein B (inverse correlation) and (ii) HDL Cholesterol and LpAI (positive correlation). The amount of variation explained by the final models was modest, ranging from 4% to 15%. In conclusion, in this Northern Ireland population, habitual diet contributes to little of the variation in plasma levels of lipids, apoproteins and lipoparticles.

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    KEE F, WESTON J, MCCRUM EE, MCMASTER D, YARNELL J, FRUCHART JC et al. THE EFFECT OF DIET ON LIPID, APOPROTEIN AND LIPOPARTICLE VARIATION IN THE ECTIM STUDY IN BELFAST. 1995;43(1):18-25.