The deposition of strontium and zinc Co-substituted hydroxyapatite coatings

L. Robinson, K. Salma-Ancane, L. Stipniece, Brian Meenan, A. R. Boyd

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The in vitro and in vivo performance of hydroxyapatite (HAp) coatings can be modified by the addition of different trace ions, such as silicon (Si), lithium (Li), magnesium (Mg), zinc (Zn) or strontium (Sr) into the HAp lattice, to more closely mirror the complex chemistry of human bone. To date, most of the work in the literature has considered single ion-substituted materials and coatings,with limited reports on co-substituted calcium phosphate systems. The aim of this study was to investigate the potential of radio frequency magnetron sputtering to deposit Sr and Zn co-substituted HAp coatings using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD) and X-ray photoelectron spectroscopy (XPS). The FTIR and XPS results highlight that all of the Sr, Zn and Sr-Zn co-substituted surfaces produced are all dehydroxylated and are calcium deficient. All of the coatings contained HPO4 2− groups, however; only the pure HAp coating andthe Sr substituted HAp coating contained additional CO3 2− groups. The XRD results highlight that none of the coatings produced in this study contain any other impurity CaP phases, showing peaks corresponding to that of ICDD file #01-072-1243 for HAp, albeit shifted to lower 2θ valuesdue to the incorporation of Sr into the HAp lattice for Ca (in the Sr and Sr-Zn co-substituted surfaces only). Therefore, the results here clearly show that RF magnetron sputtering offers a simple means to deliver Sr and Zn co-substituted HAp coatings with enhanced surface properties.
LanguageEnglish
Pages1-14
JournalJournal of Materials Science: Materials in Medicine
Volume28
Issue number51
Early online date14 Feb 2017
DOIs
Publication statusPublished - 31 Mar 2017

Fingerprint

Strontium
Durapatite
Hydroxyapatite
Zinc
Coatings
Photoelectron Spectroscopy
Fourier Transform Infrared Spectroscopy
X-Ray Diffraction
Strontium deposits
Magnetron sputtering
Ions
Fourier transform infrared spectroscopy
X ray photoelectron spectroscopy
Zinc deposits
Surface Properties
Silicon
Radio
Lithium
X ray diffraction
Magnesium

Keywords

  • RF magnetron sputtering
  • hydroxyapatite coating
  • co-deposition
  • co-substitution
  • strontium
  • zinc

Cite this

@article{6a7559896d754b16965d69386e88d054,
title = "The deposition of strontium and zinc Co-substituted hydroxyapatite coatings",
abstract = "The in vitro and in vivo performance of hydroxyapatite (HAp) coatings can be modified by the addition of different trace ions, such as silicon (Si), lithium (Li), magnesium (Mg), zinc (Zn) or strontium (Sr) into the HAp lattice, to more closely mirror the complex chemistry of human bone. To date, most of the work in the literature has considered single ion-substituted materials and coatings,with limited reports on co-substituted calcium phosphate systems. The aim of this study was to investigate the potential of radio frequency magnetron sputtering to deposit Sr and Zn co-substituted HAp coatings using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD) and X-ray photoelectron spectroscopy (XPS). The FTIR and XPS results highlight that all of the Sr, Zn and Sr-Zn co-substituted surfaces produced are all dehydroxylated and are calcium deficient. All of the coatings contained HPO4 2− groups, however; only the pure HAp coating andthe Sr substituted HAp coating contained additional CO3 2− groups. The XRD results highlight that none of the coatings produced in this study contain any other impurity CaP phases, showing peaks corresponding to that of ICDD file #01-072-1243 for HAp, albeit shifted to lower 2θ valuesdue to the incorporation of Sr into the HAp lattice for Ca (in the Sr and Sr-Zn co-substituted surfaces only). Therefore, the results here clearly show that RF magnetron sputtering offers a simple means to deliver Sr and Zn co-substituted HAp coatings with enhanced surface properties.",
keywords = "RF magnetron sputtering, hydroxyapatite coating, co-deposition, co-substitution, strontium, zinc",
author = "L. Robinson and K. Salma-Ancane and L. Stipniece and Brian Meenan and Boyd, {A. R.}",
note = "Compliant in UIR; evidence uploaded to 'Other files' Date: Jan 04, 2017 To: {"}Adrian Boyd{"} ar.boyd@ulster.ac.uk From: {"}Journal of Materials Science: Materials in Medicine (JMSM){"} Divya.Ananthanarayanan@springer.com Subject: JMSM-D-16-00530R1 - Editor Decision Dear Dr. Boyd, We are pleased to inform you that your manuscript, {"}The Deposition of Strontium and Zinc Co-substituted Hydroxyapatite Coatings{"}, has been accepted for publication in Journal of Materials Science: Materials in Medicine. You will receive an e-mail from Springer in due course with regards to the following items: 1.Offprints 2.Colour figures 3.Transfer of Copyright Please remember to quote the manuscript number, JMSM-D-16-00530R1, whenever inquiring about your manuscript. Best regards, Divya Ananthanarayanan Springer Journals Editorial Office Journal of Materials Science: Materials in Medicine Reference text: 1. Dorozhkin SV. Calcium orthophosphates: Applications in Nature, Biology, and Medicine. Singapore: Pan Stanford Publishing; 2012. 2. Kokubo T. Bioceramics and their clinical applications. England: Woodhead Publishing; 2008. 3. Ben-Nissan B, Choi AH, Roest R, Latella BA, Bendavid A. Adhesion of hydroxyapatite on titanium medical implants. In: Mucalo M, editor. Hydroxyapatite (HAp) for biomedical applications. Cambridge: Woodhead publishing series in biomaterials; 2015. pp. 21–52. 4. Zhang BGX, Myers DE, Wallace GG, Brandt M, Choong PFM. Bioactive coatings for orthopaedic implants—recent trends in development of implant coatings. Int J Mol Sci. 2014;15:11878–921. 5. Drevet R, Benhayoune H. Pulsed electrodeposition for the synthesis of strontium-substituted calcium phosphate coatings with improved dissolution properties. Mater Sci Eng C Mater Biol Appl. 2013;33:4260–5. 6. Lindahl C, Pujari-Palmer S, Hoess A, Ott M, Engqvist H, Xia W. The influence of Sr content in calcium phosphate coatings. Mater Sci Eng C. 2015;53:322–30. 7. Shepherd JH, Shepherd DV, Best SM. Substituted hydroxyapatites for bone repair. J Mater Sci: Mater Med. 2012;23:2335–47. 8. Mourińo V, Cattalini JP, Boccaccini AR. Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments. J Roy Soc Interface. 2012;9:401–19. 9. Boanini E, Gazzano M, Bigi A. Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomater. 2010;6:1882–94. 10. Stanić V, Dimitrijević S, Antić-Stanković J, Mitrić M, Jokić B, Plećaš IB, et al. Synthesis, characterization and antimicrobial activity of copper and zinc-doped hydroxyapatite nanopowders. Appl Surf Sci. 2010;256:6083–9. 11. Shanmugam S, Gopal B. Copper substituted hydroxyapatite and fluorapatite: synthesis, characterization and antimicrobial properties. Ceram Int. 2014;40:15655–62. 12. Feng QL, Cui FZ, Kim TN, Kim JW. Ag-substituted hydroxyapatite coatings with both antimicrobial effects and biocompatibility. J Mater Sci Lett. 1999;18:559–61. 13. Gopi D, Shinyjoy E, Kavitha L. Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications. Spectrochim Acta—Part A Mol Biomol Spectrosc. 2014;127:286–91. 14. Kannan S, Goetz-Neunhoegffer F, Neubauer J, Ferreira JMF. Cosubstituition of zinc and strontium in β-triclacium phosphate: synthesis and charaterisation. Jn Amer Cer Soc. 2011;94:230–5. 15. Tang XL, Xiao XF, Liu RF. Structural characterization of siliconsubstituted hydroxyapatite synthesized by a hydrothermal method. Mater Lett. 2005;59(29-30):3841–6. 16. Tian T, Jiang D, Zhang J, Lin Q. Synthesis of Si-substituted hydroxyapatite by a wet mechanochemical method. Mater Sci Eng C. 2008;28(1):57–63. 17. Wakamura M, Kandori K, Ishikawa T. Surface structure and composition of calcium hydroxyapatites substituted with Al(III), La(III) and Fe(III) ions. Colloids Surf A. 2000;164(2-3): 297–305. 18. 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year = "2017",
month = "3",
day = "31",
doi = "10.1007/s10856-017-5846-2",
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The deposition of strontium and zinc Co-substituted hydroxyapatite coatings. / Robinson, L.; Salma-Ancane, K.; Stipniece, L.; Meenan, Brian; Boyd, A. R.

In: Journal of Materials Science: Materials in Medicine, Vol. 28, No. 51, 31.03.2017, p. 1-14.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The deposition of strontium and zinc Co-substituted hydroxyapatite coatings

AU - Robinson, L.

AU - Salma-Ancane, K.

AU - Stipniece, L.

AU - Meenan, Brian

AU - Boyd, A. R.

N1 - Compliant in UIR; evidence uploaded to 'Other files' Date: Jan 04, 2017 To: "Adrian Boyd" ar.boyd@ulster.ac.uk From: "Journal of Materials Science: Materials in Medicine (JMSM)" Divya.Ananthanarayanan@springer.com Subject: JMSM-D-16-00530R1 - Editor Decision Dear Dr. Boyd, We are pleased to inform you that your manuscript, "The Deposition of Strontium and Zinc Co-substituted Hydroxyapatite Coatings", has been accepted for publication in Journal of Materials Science: Materials in Medicine. You will receive an e-mail from Springer in due course with regards to the following items: 1.Offprints 2.Colour figures 3.Transfer of Copyright Please remember to quote the manuscript number, JMSM-D-16-00530R1, whenever inquiring about your manuscript. Best regards, Divya Ananthanarayanan Springer Journals Editorial Office Journal of Materials Science: Materials in Medicine Reference text: 1. Dorozhkin SV. Calcium orthophosphates: Applications in Nature, Biology, and Medicine. Singapore: Pan Stanford Publishing; 2012. 2. Kokubo T. Bioceramics and their clinical applications. England: Woodhead Publishing; 2008. 3. Ben-Nissan B, Choi AH, Roest R, Latella BA, Bendavid A. Adhesion of hydroxyapatite on titanium medical implants. In: Mucalo M, editor. Hydroxyapatite (HAp) for biomedical applications. Cambridge: Woodhead publishing series in biomaterials; 2015. pp. 21–52. 4. Zhang BGX, Myers DE, Wallace GG, Brandt M, Choong PFM. Bioactive coatings for orthopaedic implants—recent trends in development of implant coatings. Int J Mol Sci. 2014;15:11878–921. 5. Drevet R, Benhayoune H. Pulsed electrodeposition for the synthesis of strontium-substituted calcium phosphate coatings with improved dissolution properties. Mater Sci Eng C Mater Biol Appl. 2013;33:4260–5. 6. Lindahl C, Pujari-Palmer S, Hoess A, Ott M, Engqvist H, Xia W. The influence of Sr content in calcium phosphate coatings. Mater Sci Eng C. 2015;53:322–30. 7. Shepherd JH, Shepherd DV, Best SM. Substituted hydroxyapatites for bone repair. J Mater Sci: Mater Med. 2012;23:2335–47. 8. Mourińo V, Cattalini JP, Boccaccini AR. Metallic ions as therapeutic agents in tissue engineering scaffolds: an overview of their biological applications and strategies for new developments. J Roy Soc Interface. 2012;9:401–19. 9. Boanini E, Gazzano M, Bigi A. Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomater. 2010;6:1882–94. 10. Stanić V, Dimitrijević S, Antić-Stanković J, Mitrić M, Jokić B, Plećaš IB, et al. Synthesis, characterization and antimicrobial activity of copper and zinc-doped hydroxyapatite nanopowders. Appl Surf Sci. 2010;256:6083–9. 11. Shanmugam S, Gopal B. Copper substituted hydroxyapatite and fluorapatite: synthesis, characterization and antimicrobial properties. Ceram Int. 2014;40:15655–62. 12. Feng QL, Cui FZ, Kim TN, Kim JW. Ag-substituted hydroxyapatite coatings with both antimicrobial effects and biocompatibility. J Mater Sci Lett. 1999;18:559–61. 13. Gopi D, Shinyjoy E, Kavitha L. Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications. Spectrochim Acta—Part A Mol Biomol Spectrosc. 2014;127:286–91. 14. Kannan S, Goetz-Neunhoegffer F, Neubauer J, Ferreira JMF. Cosubstituition of zinc and strontium in β-triclacium phosphate: synthesis and charaterisation. Jn Amer Cer Soc. 2011;94:230–5. 15. Tang XL, Xiao XF, Liu RF. Structural characterization of siliconsubstituted hydroxyapatite synthesized by a hydrothermal method. Mater Lett. 2005;59(29-30):3841–6. 16. Tian T, Jiang D, Zhang J, Lin Q. Synthesis of Si-substituted hydroxyapatite by a wet mechanochemical method. Mater Sci Eng C. 2008;28(1):57–63. 17. Wakamura M, Kandori K, Ishikawa T. Surface structure and composition of calcium hydroxyapatites substituted with Al(III), La(III) and Fe(III) ions. Colloids Surf A. 2000;164(2-3): 297–305. 18. 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PY - 2017/3/31

Y1 - 2017/3/31

N2 - The in vitro and in vivo performance of hydroxyapatite (HAp) coatings can be modified by the addition of different trace ions, such as silicon (Si), lithium (Li), magnesium (Mg), zinc (Zn) or strontium (Sr) into the HAp lattice, to more closely mirror the complex chemistry of human bone. To date, most of the work in the literature has considered single ion-substituted materials and coatings,with limited reports on co-substituted calcium phosphate systems. The aim of this study was to investigate the potential of radio frequency magnetron sputtering to deposit Sr and Zn co-substituted HAp coatings using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD) and X-ray photoelectron spectroscopy (XPS). The FTIR and XPS results highlight that all of the Sr, Zn and Sr-Zn co-substituted surfaces produced are all dehydroxylated and are calcium deficient. All of the coatings contained HPO4 2− groups, however; only the pure HAp coating andthe Sr substituted HAp coating contained additional CO3 2− groups. The XRD results highlight that none of the coatings produced in this study contain any other impurity CaP phases, showing peaks corresponding to that of ICDD file #01-072-1243 for HAp, albeit shifted to lower 2θ valuesdue to the incorporation of Sr into the HAp lattice for Ca (in the Sr and Sr-Zn co-substituted surfaces only). Therefore, the results here clearly show that RF magnetron sputtering offers a simple means to deliver Sr and Zn co-substituted HAp coatings with enhanced surface properties.

AB - The in vitro and in vivo performance of hydroxyapatite (HAp) coatings can be modified by the addition of different trace ions, such as silicon (Si), lithium (Li), magnesium (Mg), zinc (Zn) or strontium (Sr) into the HAp lattice, to more closely mirror the complex chemistry of human bone. To date, most of the work in the literature has considered single ion-substituted materials and coatings,with limited reports on co-substituted calcium phosphate systems. The aim of this study was to investigate the potential of radio frequency magnetron sputtering to deposit Sr and Zn co-substituted HAp coatings using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD) and X-ray photoelectron spectroscopy (XPS). The FTIR and XPS results highlight that all of the Sr, Zn and Sr-Zn co-substituted surfaces produced are all dehydroxylated and are calcium deficient. All of the coatings contained HPO4 2− groups, however; only the pure HAp coating andthe Sr substituted HAp coating contained additional CO3 2− groups. The XRD results highlight that none of the coatings produced in this study contain any other impurity CaP phases, showing peaks corresponding to that of ICDD file #01-072-1243 for HAp, albeit shifted to lower 2θ valuesdue to the incorporation of Sr into the HAp lattice for Ca (in the Sr and Sr-Zn co-substituted surfaces only). Therefore, the results here clearly show that RF magnetron sputtering offers a simple means to deliver Sr and Zn co-substituted HAp coatings with enhanced surface properties.

KW - RF magnetron sputtering

KW - hydroxyapatite coating

KW - co-deposition

KW - co-substitution

KW - strontium

KW - zinc

U2 - 10.1007/s10856-017-5846-2

DO - 10.1007/s10856-017-5846-2

M3 - Article

VL - 28

SP - 1

EP - 14

JO - Journal of Materials Science: Materials in Medicine

T2 - Journal of Materials Science: Materials in Medicine

JF - Journal of Materials Science: Materials in Medicine

SN - 0957-4530

IS - 51

ER -