The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

N. Raule, F. Sevini, S. Li, A. Barbieri, F. Tallaro, L. Lomartire, D. Vianello, A. Montesanto, J.S. Moilanen, V. Bezrukov, H. Blanché, A. Hervonen, K. Christensen, L. Deiana, E.S. Gonos, T.B.L. Kirkwood, P. Kristensen, A. Leon, P.G. Pelicci, M. PoulainI.M. Rea, J. Remacle, J.M. Robine, S. Schreiber, E. Sikora, P. Eline Slagboom, L. Spazzafumo, M. Antonietta Stazi, O. Toussaint, J.W. Vaupel, G. Rose, K. Majamaa, M. Perola, T.E. Johnson, L. Bolund, H. Yang, G. Passarino, C. Franceschi

    Research output: Contribution to journalArticlepeer-review

    68 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)401-407
    JournalAging Cell
    Issue number3
    Publication statusPublished - 17 Dec 2013


    • Genetics of longevity
    • Longevity
    • Mitochondrial DNA
    • MtDNA sequencing
    • Oxidative phosphorylation

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