The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study

Katalin Ujhelyi Gomez; Orla McBride; Emmert Roberts; Colin Angus; Katherine Keyes; Colin Drummond; Iain Buchan; Kate Fleming; Ian Gilmore; Kim Donoghue; Laura Bonnet; Laura Goodwin

doi:10.1186/s12888-023-04577-3

The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study

Katalin Ujhelyi Gomez
, Orla McBride
, Emmert Roberts
, Colin Angus
, Katherine Keyes
, Colin Drummond
, Iain Buchan
, Kate Fleming
, Ian Gilmore
, Kim Donoghue
, Laura Bonnet
, Laura Goodwin

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

71 Downloads (Pure)

Abstract

Background: There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England’s general population. Methods: Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses. Results: Five clusters were identified with statistically distinct and clinically meaningful disease patterns: ‘Physically Healthy’ (76.62%), ‘Emerging Multimorbidity’ (3.12%), ‘Hypertension & Arthritis’ (14.28%), ‘Digestive & Bowel Problems’’ (3.17%), and ‘Complex Multimorbidity’ (2.8%). Having a mental health problem was associated with increased odds of ‘Digestive & Bowel Problems’ (adjusted multinomial odds ratio (AMOR) = 1.58; 95% CI [1.15–2.17]) and ‘Complex Multimorbidity’ (AMOR = 2.02; 95% CI [1.49–2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of ‘Digestive & Bowel Problems’ (AMOR = 2.64; 95% CI [1.68–4.15]) and ‘Complex Multimorbidity’ (AMOR = 2.62; 95% CI [1.61–4.23]). Conclusions: Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services.

Original language	English
Article number	89
Pages (from-to)	1-14
Number of pages	14
Journal	BMC Psychiatry
Volume	23
Issue number	1
Early online date	6 Feb 2023
DOIs	https://doi.org/10.1186/s12888-023-04577-3
Publication status	Published online - 6 Feb 2023

Bibliographical note

Funding Information:
Katalin Ujhelyi Gomez is funded by the National Institute for Health Research (NIHR) Applied Research Collaboration North West Coast (ARC NWC) at the University of Liverpool. The funding body had no role in the design of the study and collection, analysis, and interpretation of data or in writing the manuscript.

Funding Information:
This work was funded by the Strategic Priority Fund “Tackling multimorbidity at scale” programme [grant number MR/V005170/1] delivered by the Medical Research Council and the National Institute for Health and Care Research in partnership with the Economic and Social Research Council and in collaboration with the Engineering and Physical Sciences Research Council.

Publisher Copyright:
© 2023, The Author(s).

Funding

Funding Information: Katalin Ujhelyi Gomez is funded by the National Institute for Health Research (NIHR) Applied Research Collaboration North West Coast (ARC NWC) at the University of Liverpool. The funding body had no role in the design of the study and collection, analysis, and interpretation of data or in writing the manuscript. Funding Information: This work was funded by the Strategic Priority Fund “Tackling multimorbidity at scale” programme [grant number MR/V005170/1] delivered by the Medical Research Council and the National Institute for Health and Care Research in partnership with the Economic and Social Research Council and in collaboration with the Engineering and Physical Sciences Research Council. Publisher Copyright: © 2023, The Author(s).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Research
Multimorbidity
Mental health
Alcohol
Physical health
Latent class analysis
Cross-Sectional Studies
Humans
Mental Health
Alcoholism/epidemiology
Adult
Health Status
Cluster Analysis
Alcoholism
Latent Class Analysis
Physical Health

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12888_2023_Article_4577.pdfFinal published version, 1.7 MBLicence: CC BY

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Gomez, K. U., McBride, O., Roberts, E., Angus, C., Keyes, K., Drummond, C., Buchan, I., Fleming, K., Gilmore, I., Donoghue, K., Bonnet, L., & Goodwin, L. (2023). The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study. BMC Psychiatry, 23(1), 1-14. Article 89. Advance online publication. https://doi.org/10.1186/s12888-023-04577-3

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title = "The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study",

abstract = "Background: There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England{\textquoteright}s general population. Methods: Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses. Results: Five clusters were identified with statistically distinct and clinically meaningful disease patterns: {\textquoteleft}Physically Healthy{\textquoteright} (76.62\%), {\textquoteleft}Emerging Multimorbidity{\textquoteright} (3.12\%), {\textquoteleft}Hypertension \& Arthritis{\textquoteright} (14.28\%), {\textquoteleft}Digestive \& Bowel Problems{\textquoteright}{\textquoteright} (3.17\%), and {\textquoteleft}Complex Multimorbidity{\textquoteright} (2.8\%). Having a mental health problem was associated with increased odds of {\textquoteleft}Digestive \& Bowel Problems{\textquoteright} (adjusted multinomial odds ratio (AMOR) = 1.58; 95\% CI [1.15–2.17]) and {\textquoteleft}Complex Multimorbidity{\textquoteright} (AMOR = 2.02; 95\% CI [1.49–2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of {\textquoteleft}Digestive \& Bowel Problems{\textquoteright} (AMOR = 2.64; 95\% CI [1.68–4.15]) and {\textquoteleft}Complex Multimorbidity{\textquoteright} (AMOR = 2.62; 95\% CI [1.61–4.23]). Conclusions: Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services.",

keywords = "Research, Multimorbidity, Mental health, Alcohol, Physical health, Latent class analysis, Cross-Sectional Studies, Humans, Mental Health, Alcoholism/epidemiology, Adult, Health Status, Cluster Analysis, Alcoholism, Latent Class Analysis, Physical Health",

author = "Gomez, \{Katalin Ujhelyi\} and Orla McBride and Emmert Roberts and Colin Angus and Katherine Keyes and Colin Drummond and Iain Buchan and Kate Fleming and Ian Gilmore and Kim Donoghue and Laura Bonnet and Laura Goodwin",

note = "Funding Information: Katalin Ujhelyi Gomez is funded by the National Institute for Health Research (NIHR) Applied Research Collaboration North West Coast (ARC NWC) at the University of Liverpool. The funding body had no role in the design of the study and collection, analysis, and interpretation of data or in writing the manuscript. Funding Information: This work was funded by the Strategic Priority Fund “Tackling multimorbidity at scale” programme [grant number MR/V005170/1] delivered by the Medical Research Council and the National Institute for Health and Care Research in partnership with the Economic and Social Research Council and in collaboration with the Engineering and Physical Sciences Research Council. Publisher Copyright: {\textcopyright} 2023, The Author(s).",

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month = feb,

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doi = "10.1186/s12888-023-04577-3",

language = "English",

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Gomez, KU, McBride, O, Roberts, E, Angus, C, Keyes, K, Drummond, C, Buchan, I, Fleming, K, Gilmore, I, Donoghue, K, Bonnet, L & Goodwin, L 2023, 'The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study', BMC Psychiatry, vol. 23, no. 1, 89, pp. 1-14. https://doi.org/10.1186/s12888-023-04577-3

TY - JOUR

T1 - The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study

AU - Gomez, Katalin Ujhelyi

AU - McBride, Orla

AU - Roberts, Emmert

AU - Angus, Colin

AU - Keyes, Katherine

AU - Drummond, Colin

AU - Buchan, Iain

AU - Fleming, Kate

AU - Gilmore, Ian

AU - Donoghue, Kim

AU - Bonnet, Laura

AU - Goodwin, Laura

N1 - Funding Information: Katalin Ujhelyi Gomez is funded by the National Institute for Health Research (NIHR) Applied Research Collaboration North West Coast (ARC NWC) at the University of Liverpool. The funding body had no role in the design of the study and collection, analysis, and interpretation of data or in writing the manuscript. Funding Information: This work was funded by the Strategic Priority Fund “Tackling multimorbidity at scale” programme [grant number MR/V005170/1] delivered by the Medical Research Council and the National Institute for Health and Care Research in partnership with the Economic and Social Research Council and in collaboration with the Engineering and Physical Sciences Research Council. Publisher Copyright: © 2023, The Author(s).

PY - 2023/2/6

Y1 - 2023/2/6

N2 - Background: There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England’s general population. Methods: Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses. Results: Five clusters were identified with statistically distinct and clinically meaningful disease patterns: ‘Physically Healthy’ (76.62%), ‘Emerging Multimorbidity’ (3.12%), ‘Hypertension & Arthritis’ (14.28%), ‘Digestive & Bowel Problems’’ (3.17%), and ‘Complex Multimorbidity’ (2.8%). Having a mental health problem was associated with increased odds of ‘Digestive & Bowel Problems’ (adjusted multinomial odds ratio (AMOR) = 1.58; 95% CI [1.15–2.17]) and ‘Complex Multimorbidity’ (AMOR = 2.02; 95% CI [1.49–2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of ‘Digestive & Bowel Problems’ (AMOR = 2.64; 95% CI [1.68–4.15]) and ‘Complex Multimorbidity’ (AMOR = 2.62; 95% CI [1.61–4.23]). Conclusions: Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services.

AB - Background: There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England’s general population. Methods: Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses. Results: Five clusters were identified with statistically distinct and clinically meaningful disease patterns: ‘Physically Healthy’ (76.62%), ‘Emerging Multimorbidity’ (3.12%), ‘Hypertension & Arthritis’ (14.28%), ‘Digestive & Bowel Problems’’ (3.17%), and ‘Complex Multimorbidity’ (2.8%). Having a mental health problem was associated with increased odds of ‘Digestive & Bowel Problems’ (adjusted multinomial odds ratio (AMOR) = 1.58; 95% CI [1.15–2.17]) and ‘Complex Multimorbidity’ (AMOR = 2.02; 95% CI [1.49–2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of ‘Digestive & Bowel Problems’ (AMOR = 2.64; 95% CI [1.68–4.15]) and ‘Complex Multimorbidity’ (AMOR = 2.62; 95% CI [1.61–4.23]). Conclusions: Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services.

KW - Research

KW - Multimorbidity

KW - Mental health

KW - Alcohol

KW - Physical health

KW - Latent class analysis

KW - Cross-Sectional Studies

KW - Humans

KW - Mental Health

KW - Alcoholism/epidemiology

KW - Adult

KW - Health Status

KW - Cluster Analysis

KW - Alcoholism

KW - Latent Class Analysis

KW - Physical Health

UR - https://www.scopus.com/pages/publications/85147460919

U2 - 10.1186/s12888-023-04577-3

DO - 10.1186/s12888-023-04577-3

M3 - Article

C2 - 36747152

SN - 1471-244X

VL - 23

SP - 1

EP - 14

JO - BMC Psychiatry

JF - BMC Psychiatry

IS - 1

M1 - 89

ER -

The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

Access to Document

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