Targeting hypoxia in prostate cancer cells to increase treatment efficacy

Heather Nesbitt; niall byrne; Jenny Worthington; Stephanie McKeown; Declan McKenna

Targeting hypoxia in prostate cancer cells to increase treatment efficacy

Heather Nesbitt, niall byrne, Jenny Worthington, Stephanie McKeown, Declan McKenna

Research output: Contribution to journal › Article › peer-review

Abstract

Androgen deprivation therapy e.g. bicalutamide (BCA) is widely used to treat advanced prostate cancer; however, within 1.5-3 years most tumours have progressed to androgen independence (Abate-Shen C; Genes Dev 14, 2410-2434; 2000). Previously we showed that daily BCA causes an initial profound hypoxia (

Original language	English
Pages (from-to)	209-210
Journal	Ulster Medical Journal
Volume	84
Issue number	3
Publication status	Published (in print/issue) - Oct 2015

Keywords

hypoxia
uHAP
OCT1002
bicalutamide
prostate cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642251/

Cite this

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title = "Targeting hypoxia in prostate cancer cells to increase treatment efficacy",

abstract = "Androgen deprivation therapy e.g. bicalutamide (BCA) is widely used to treat advanced prostate cancer; however, within 1.5-3 years most tumours have progressed to androgen independence (Abate-Shen C; Genes Dev 14, 2410-2434; 2000). Previously we showed that daily BCA causes an initial profound hypoxia (",

keywords = "hypoxia, uHAP, OCT1002, bicalutamide, prostate cancer",

author = "Heather Nesbitt and niall byrne and Jenny Worthington and Stephanie McKeown and Declan McKenna",

year = "2015",

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language = "English",

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T1 - Targeting hypoxia in prostate cancer cells to increase treatment efficacy

AU - Nesbitt, Heather

AU - byrne, niall

AU - Worthington, Jenny

AU - McKeown, Stephanie

AU - McKenna, Declan

PY - 2015/10

Y1 - 2015/10

N2 - Androgen deprivation therapy e.g. bicalutamide (BCA) is widely used to treat advanced prostate cancer; however, within 1.5-3 years most tumours have progressed to androgen independence (Abate-Shen C; Genes Dev 14, 2410-2434; 2000). Previously we showed that daily BCA causes an initial profound hypoxia (

AB - Androgen deprivation therapy e.g. bicalutamide (BCA) is widely used to treat advanced prostate cancer; however, within 1.5-3 years most tumours have progressed to androgen independence (Abate-Shen C; Genes Dev 14, 2410-2434; 2000). Previously we showed that daily BCA causes an initial profound hypoxia (

KW - hypoxia

KW - uHAP

KW - OCT1002

KW - bicalutamide

KW - prostate cancer

M3 - Article

SN - 2046-4207

VL - 84

SP - 209

EP - 210

JO - Ulster Medical Journal

JF - Ulster Medical Journal

IS - 3

ER -

Targeting hypoxia in prostate cancer cells to increase treatment efficacy

Abstract

Keywords

UN SDGs

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