Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients

David Gibson, Sarah Blelock, Jim Curry, Sorcha Finnegan, Adrienne Healy, Catriona Scaife, Catherine McAllister, Stephen Pennington, Michael Dunn, Madeleine Rooney

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Background: Synovial fluid (SF) is a potential source of novel biomarkers formany arthritic disorders involving joint inflammation, including Juvenile IdiopathicArthritis (JIA). We first compared the distinctive protein expression patterns of localjoint inflammation in SF with systemic profiles within matched plasma samples.Preliminary investigations were performed into whether local or systemic proteome‘fingerprints’ could distinguish between oligoarticular, extended oligoarticular andpolyarticular forms of this chronic juvenile disease.Methods: In this study we analysed matched SF and plasma samples obtainedfrom 10 newly diagnosed JIA patients (
    LanguageEnglish
    Title of host publicationUnknown Host Publication
    Pagesii27
    Number of pages1
    Volume47
    Publication statusPublished - 2008
    EventBritish Society for Rheumatology - Liverpool
    Duration: 1 Jan 2008 → …

    Conference

    ConferenceBritish Society for Rheumatology
    Period1/01/08 → …

    Fingerprint

    Juvenile Arthritis
    Synovial Fluid
    Proteome
    Inflammation
    Dermatoglyphics
    Arthritis
    Chronic Disease
    Joints
    Biomarkers
    Proteins

    Keywords

    • Juvenile arthritis
    • Synovial fluid
    • proteome
    • bioinformatics

    Cite this

    Gibson, D., Blelock, S., Curry, J., Finnegan, S., Healy, A., Scaife, C., ... Rooney, M. (2008). Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients. In Unknown Host Publication (Vol. 47, pp. ii27)
    Gibson, David ; Blelock, Sarah ; Curry, Jim ; Finnegan, Sorcha ; Healy, Adrienne ; Scaife, Catriona ; McAllister, Catherine ; Pennington, Stephen ; Dunn, Michael ; Rooney, Madeleine. / Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients. Unknown Host Publication. Vol. 47 2008. pp. ii27
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    abstract = "Background: Synovial fluid (SF) is a potential source of novel biomarkers formany arthritic disorders involving joint inflammation, including Juvenile IdiopathicArthritis (JIA). We first compared the distinctive protein expression patterns of localjoint inflammation in SF with systemic profiles within matched plasma samples.Preliminary investigations were performed into whether local or systemic proteome‘fingerprints’ could distinguish between oligoarticular, extended oligoarticular andpolyarticular forms of this chronic juvenile disease.Methods: In this study we analysed matched SF and plasma samples obtainedfrom 10 newly diagnosed JIA patients (",
    keywords = "Juvenile arthritis, Synovial fluid, proteome, bioinformatics",
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    Gibson, D, Blelock, S, Curry, J, Finnegan, S, Healy, A, Scaife, C, McAllister, C, Pennington, S, Dunn, M & Rooney, M 2008, Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients. in Unknown Host Publication. vol. 47, pp. ii27, British Society for Rheumatology, 1/01/08.

    Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients. / Gibson, David; Blelock, Sarah; Curry, Jim; Finnegan, Sorcha; Healy, Adrienne; Scaife, Catriona; McAllister, Catherine; Pennington, Stephen; Dunn, Michael; Rooney, Madeleine.

    Unknown Host Publication. Vol. 47 2008. p. ii27.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    TY - GEN

    T1 - Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients

    AU - Gibson, David

    AU - Blelock, Sarah

    AU - Curry, Jim

    AU - Finnegan, Sorcha

    AU - Healy, Adrienne

    AU - Scaife, Catriona

    AU - McAllister, Catherine

    AU - Pennington, Stephen

    AU - Dunn, Michael

    AU - Rooney, Madeleine

    PY - 2008

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    N2 - Background: Synovial fluid (SF) is a potential source of novel biomarkers formany arthritic disorders involving joint inflammation, including Juvenile IdiopathicArthritis (JIA). We first compared the distinctive protein expression patterns of localjoint inflammation in SF with systemic profiles within matched plasma samples.Preliminary investigations were performed into whether local or systemic proteome‘fingerprints’ could distinguish between oligoarticular, extended oligoarticular andpolyarticular forms of this chronic juvenile disease.Methods: In this study we analysed matched SF and plasma samples obtainedfrom 10 newly diagnosed JIA patients (

    AB - Background: Synovial fluid (SF) is a potential source of novel biomarkers formany arthritic disorders involving joint inflammation, including Juvenile IdiopathicArthritis (JIA). We first compared the distinctive protein expression patterns of localjoint inflammation in SF with systemic profiles within matched plasma samples.Preliminary investigations were performed into whether local or systemic proteome‘fingerprints’ could distinguish between oligoarticular, extended oligoarticular andpolyarticular forms of this chronic juvenile disease.Methods: In this study we analysed matched SF and plasma samples obtainedfrom 10 newly diagnosed JIA patients (

    KW - Juvenile arthritis

    KW - Synovial fluid

    KW - proteome

    KW - bioinformatics

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    BT - Unknown Host Publication

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    Gibson D, Blelock S, Curry J, Finnegan S, Healy A, Scaife C et al. Synovial fluid proteome expression patterns segregate juvenile idiopathic arthritis patients. In Unknown Host Publication. Vol. 47. 2008. p. ii27