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Structure aware graph community cluster pruning for efficient neural network compression in Parkinson’s disease diagnosis

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Abstract

Deep neural networks in medical and edge environments often face computational and memory constraints, which necessitate effective model compression. Neural network pruning is a widely used solution, but conventional methods often rely on magnitude-based or random criteria that can remove entire functional groups of neurons and reduce model performance. This study introduces Graph-Community Cluster Pruning (GCCP), a structured pruning framework that constructs neuron activation similarity graphs and employs Louvain community detection to identify functionally cohesive groups. Within each community, neurons are ranked using gradient-weighted saliency, enabling the removal of redundancies while retaining representative units essential for preserving functional diversity. We applied proposed GCCP to Parkinson's disease detection using the publicly available UCI benchmark voice dataset and achieved a 37.23% reduction in parameters and a 37.84% reduction in Floating Point Operations (FLOPs), while maintaining test accuracy (94.87%) and AUC (0.969). Comparative evaluations demonstrate that GCCP consistently outperforms conventional pruning methods, particularly under high compression ratios, and provides interpretable insights into neural specialization through community visualization. These results show that GCCP is a robust and interpretable compression method for developing resource-efficient and clinically reliable diagnostic models.

Original languageEnglish
Number of pages29
JournalScientific Reports
Early online date3 Jul 2026
DOIs
Publication statusPublished online - 3 Jul 2026

Bibliographical note

© 2026. The Author(s).

Data Availability Statement

The datasets generated and/or analyzed during the current study are available from the corresponding author
on reasonable request.

Funding

This result was supported by the "Regional Innovation System & Education (RISE)" through the Ulsan RISE Center, funded by the Ministry of Education (MOE) and the Ulsan Metropolitan City, Republic of Korea.(2025-RISE-07-001)

Keywords

  • Neural network pruning
  • Community detection
  • Louvain algorithm
  • Parkinson's disease
  • Artificial Intelligence (AI) n Medicine
  • Network compression

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