Abstract
Original language | English |
---|---|
Journal | Ceramics International |
Volume | TBC |
DOIs | |
Publication status | Published - 15 Oct 2017 |
Keywords
- Co-substitution
- Strontium
- Zinc
- Hydroxyapatite
- X-ray Photoelectron Spectroscopy (XPS)
- X-ray Diffraction (XRD)
- Nano-hydroxyapatite
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Strontium and zinc co-substituted nanophase hydroxyapatite. / Boyd, Adrian; Lowry, Naomi; Han, Yisong; Meenan, Brian.
In: Ceramics International, Vol. TBC, 15.10.2017.Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Strontium and zinc co-substituted nanophase hydroxyapatite
AU - Boyd, Adrian
AU - Lowry, Naomi
AU - Han, Yisong
AU - Meenan, Brian
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PY - 2017/10/15
Y1 - 2017/10/15
N2 - It is well documented that biological hydroxyapatite (HA) differs from pure and synthetically produced HA, and contains of a mixture of calcium phosphate (CaP) phases in addition to a range of impurity ions, such as strontium (Sr2+), zinc (Zn2+), magnesium (Mg2+), fluoride (F-) and carbonate(CO32-), but to name a few. Further to this, biological apatite is generally in the form of rod (or needle-like) crystals in the nanometre (nm) size range, typically 60 nm in length by 5–20 nm wide. In this study, a range of nano-hydroxyapatite (nHA), substituted nHA materials and co-substituted nHA (based on Sr2+ and Zn2+) were manufactured using an aqueous precipitation method. Sr2+ and Zn2+ were chosen due to the significant performance enhancements that these substitutions can deliver. The materials were then characterised using Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), X-Ray Photoelectron Spectroscopy (XPS) and Transmission Electron Microscopy (TEM) techniques. The TEM results show that all of the samples produced were nano-sized, with Zn-substituted nHA being the smallest crystals around 27 nm long and 8 nm wide. The FTIR, XRD and XPS results all confirm that the materials had undergone substitution with either Sr2+ and Zn2+, for Ca2+ within the HA lattice (or both in the case of the co-substituted materials). The FTIR results confirmed that all of the samples were carbonated, with a significant loss of hydroxylation as a consequence of the incorporation of Sr2+ and Zn2+ into the HA lattice. None of the materials synthesised here in this study contained any other impurity CaP phases. Therefore this study has shown that substituted and co-substituted nanoscale apatites can be prepared, and that the degree of substitution (and the substituting ion) can have a profound effect of the attendant materials’ properties.
AB - It is well documented that biological hydroxyapatite (HA) differs from pure and synthetically produced HA, and contains of a mixture of calcium phosphate (CaP) phases in addition to a range of impurity ions, such as strontium (Sr2+), zinc (Zn2+), magnesium (Mg2+), fluoride (F-) and carbonate(CO32-), but to name a few. Further to this, biological apatite is generally in the form of rod (or needle-like) crystals in the nanometre (nm) size range, typically 60 nm in length by 5–20 nm wide. In this study, a range of nano-hydroxyapatite (nHA), substituted nHA materials and co-substituted nHA (based on Sr2+ and Zn2+) were manufactured using an aqueous precipitation method. Sr2+ and Zn2+ were chosen due to the significant performance enhancements that these substitutions can deliver. The materials were then characterised using Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), X-Ray Photoelectron Spectroscopy (XPS) and Transmission Electron Microscopy (TEM) techniques. The TEM results show that all of the samples produced were nano-sized, with Zn-substituted nHA being the smallest crystals around 27 nm long and 8 nm wide. The FTIR, XRD and XPS results all confirm that the materials had undergone substitution with either Sr2+ and Zn2+, for Ca2+ within the HA lattice (or both in the case of the co-substituted materials). The FTIR results confirmed that all of the samples were carbonated, with a significant loss of hydroxylation as a consequence of the incorporation of Sr2+ and Zn2+ into the HA lattice. None of the materials synthesised here in this study contained any other impurity CaP phases. Therefore this study has shown that substituted and co-substituted nanoscale apatites can be prepared, and that the degree of substitution (and the substituting ion) can have a profound effect of the attendant materials’ properties.
KW - Co-substitution
KW - Strontium
KW - Zinc
KW - Hydroxyapatite
KW - X-ray Photoelectron Spectroscopy (XPS)
KW - X-ray Diffraction (XRD)
KW - Nano-hydroxyapatite
U2 - 10.1016/j.ceramint.2017.06.062
DO - 10.1016/j.ceramint.2017.06.062
M3 - Article
VL - TBC
JO - Ceramics International
JF - Ceramics International
SN - 0272-8842
ER -