Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries

Lee Smith; Jae Il Shin; Nicola Veronese; Pinar Soysal; Guillermo F López Sánchez; Damiano Pizzol; Jacopo Demurtas; Mark A Tully; Yvonne Barnett; Laurie Butler; Ai Koyanagi

doi:10.1007/s40520-022-02074-3

Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries

Lee Smith, Jae Il Shin, Nicola Veronese, Pinar Soysal, Guillermo F López Sánchez, Damiano Pizzol, Jacopo Demurtas, Mark A Tully, Yvonne Barnett, Laurie Butler, Ai Koyanagi

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

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Abstract

BACKGROUND: Sleep duration may influence risk for sarcopenia but studies on this topic are scarce, especially from low and- middle-income countries (LMICs). Thus, the aim of the present study was to investigate the association between sleep duration and sarcopenia among adults aged ≥ 65 years from five LMICs (China, Ghana, India, Russia, South Africa).

METHODS: Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. Self-reported sleep duration in the past two nights were averaged and classified as ≤ 6, > 6 to ≤ 9, and ≥ 9 h/day. Multivariable logistic regression analysis was conducted.

RESULTS: Data on 13,210 adults aged ≥ 65 years [mean (SD) age 72.6 (11.3) years; 55.0% females] were analyzed. In the overall sample, compared to > 6 to ≤ 9 h/day of sleep duration, > 9 h/day was associated with 1.70 (95% CI 1.15-2.51) and 1.75 (95% CI 1.08-2.84) times higher odds for sarcopenia and severe sarcopenia, respectively. No significant associations were observed among males, but associations were particularly pronounced among females [i.e., OR = 2.19 (95% CI 1.26-3.81) for sarcopenia, and OR = 2.26 (95% CI 1.20-4.23) for severe sarcopenia].

CONCLUSIONS: Long sleep duration was associated with an increased odds of sarcopenia and severe sarcopenia in LMICs, particularly in females. Future studies should investigate whether addressing long sleep duration among females can lead to lower risk for sarcopenia onset in LMICs.

Original language	English
Pages (from-to)	1573-1581
Number of pages	9
Journal	Aging Clinical and Experimental Research
Volume	34
Issue number	7
Early online date	1 Feb 2022
DOIs	https://doi.org/10.1007/s40520-022-02074-3
Publication status	Published online - 1 Feb 2022

Bibliographical note

Funding Information:
This paper uses data from WHO’s Study on Global Ageing and Adult Health (SAGE). SAGE is supported by the U.S. National Institute on Aging through Interagency Agreements OGHA 04034785, YA1323-08-CN-0020, Y1-AG-1005-01 and through research grants R01-AG034479 and R21-AG034263.

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Keywords

Low- and- middle income countries
Older adults
Sarcopenia
Sleep problems
Prevalence
Cross-Sectional Studies
Humans
Male
Sarcopenia/epidemiology
Sleep
Female
Developing Countries
Hand Strength

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s40520-022-02074-3

sleep duration and sarcopenia AAMAuthor Accepted Manuscript, 485 KBLicence: CC BY

Cite this

Smith, L., Shin, J. I., Veronese, N., Soysal, P., López Sánchez, G. F., Pizzol, D., Demurtas, J., Tully, M. A., Barnett, Y., Butler, L., & Koyanagi, A. (2022). Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries. Aging Clinical and Experimental Research , 34(7), 1573-1581. Advance online publication. https://doi.org/10.1007/s40520-022-02074-3

@article{fedcb5b08d3b4e3fb67eb17825c71f02,

title = "Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries",

abstract = "BACKGROUND: Sleep duration may influence risk for sarcopenia but studies on this topic are scarce, especially from low and- middle-income countries (LMICs). Thus, the aim of the present study was to investigate the association between sleep duration and sarcopenia among adults aged ≥ 65 years from five LMICs (China, Ghana, India, Russia, South Africa).METHODS: Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. Self-reported sleep duration in the past two nights were averaged and classified as ≤ 6, > 6 to ≤ 9, and ≥ 9 h/day. Multivariable logistic regression analysis was conducted.RESULTS: Data on 13,210 adults aged ≥ 65 years [mean (SD) age 72.6 (11.3) years; 55.0% females] were analyzed. In the overall sample, compared to > 6 to ≤ 9 h/day of sleep duration, > 9 h/day was associated with 1.70 (95% CI 1.15-2.51) and 1.75 (95% CI 1.08-2.84) times higher odds for sarcopenia and severe sarcopenia, respectively. No significant associations were observed among males, but associations were particularly pronounced among females [i.e., OR = 2.19 (95% CI 1.26-3.81) for sarcopenia, and OR = 2.26 (95% CI 1.20-4.23) for severe sarcopenia].CONCLUSIONS: Long sleep duration was associated with an increased odds of sarcopenia and severe sarcopenia in LMICs, particularly in females. Future studies should investigate whether addressing long sleep duration among females can lead to lower risk for sarcopenia onset in LMICs.",

keywords = "Low- and- middle income countries, Older adults, Sarcopenia, Sleep problems, Prevalence, Cross-Sectional Studies, Humans, Male, Sarcopenia/epidemiology, Sleep, Female, Developing Countries, Hand Strength",

author = "Lee Smith and Shin, {Jae Il} and Nicola Veronese and Pinar Soysal and {L{\'o}pez S{\'a}nchez}, {Guillermo F} and Damiano Pizzol and Jacopo Demurtas and Tully, {Mark A} and Yvonne Barnett and Laurie Butler and Ai Koyanagi",

note = "Funding Information: This paper uses data from WHO{\textquoteright}s Study on Global Ageing and Adult Health (SAGE). SAGE is supported by the U.S. National Institute on Aging through Interagency Agreements OGHA 04034785, YA1323-08-CN-0020, Y1-AG-1005-01 and through research grants R01-AG034479 and R21-AG034263. Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.",

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T1 - Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries

AU - Smith, Lee

AU - Shin, Jae Il

AU - Veronese, Nicola

AU - Soysal, Pinar

AU - López Sánchez, Guillermo F

AU - Pizzol, Damiano

AU - Demurtas, Jacopo

AU - Tully, Mark A

AU - Barnett, Yvonne

AU - Butler, Laurie

AU - Koyanagi, Ai

N1 - Funding Information: This paper uses data from WHO’s Study on Global Ageing and Adult Health (SAGE). SAGE is supported by the U.S. National Institute on Aging through Interagency Agreements OGHA 04034785, YA1323-08-CN-0020, Y1-AG-1005-01 and through research grants R01-AG034479 and R21-AG034263. Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.

PY - 2022/2/1

Y1 - 2022/2/1

N2 - BACKGROUND: Sleep duration may influence risk for sarcopenia but studies on this topic are scarce, especially from low and- middle-income countries (LMICs). Thus, the aim of the present study was to investigate the association between sleep duration and sarcopenia among adults aged ≥ 65 years from five LMICs (China, Ghana, India, Russia, South Africa).METHODS: Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. Self-reported sleep duration in the past two nights were averaged and classified as ≤ 6, > 6 to ≤ 9, and ≥ 9 h/day. Multivariable logistic regression analysis was conducted.RESULTS: Data on 13,210 adults aged ≥ 65 years [mean (SD) age 72.6 (11.3) years; 55.0% females] were analyzed. In the overall sample, compared to > 6 to ≤ 9 h/day of sleep duration, > 9 h/day was associated with 1.70 (95% CI 1.15-2.51) and 1.75 (95% CI 1.08-2.84) times higher odds for sarcopenia and severe sarcopenia, respectively. No significant associations were observed among males, but associations were particularly pronounced among females [i.e., OR = 2.19 (95% CI 1.26-3.81) for sarcopenia, and OR = 2.26 (95% CI 1.20-4.23) for severe sarcopenia].CONCLUSIONS: Long sleep duration was associated with an increased odds of sarcopenia and severe sarcopenia in LMICs, particularly in females. Future studies should investigate whether addressing long sleep duration among females can lead to lower risk for sarcopenia onset in LMICs.

AB - BACKGROUND: Sleep duration may influence risk for sarcopenia but studies on this topic are scarce, especially from low and- middle-income countries (LMICs). Thus, the aim of the present study was to investigate the association between sleep duration and sarcopenia among adults aged ≥ 65 years from five LMICs (China, Ghana, India, Russia, South Africa).METHODS: Cross-sectional, community-based data from the WHO study on global ageing and adult health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. Self-reported sleep duration in the past two nights were averaged and classified as ≤ 6, > 6 to ≤ 9, and ≥ 9 h/day. Multivariable logistic regression analysis was conducted.RESULTS: Data on 13,210 adults aged ≥ 65 years [mean (SD) age 72.6 (11.3) years; 55.0% females] were analyzed. In the overall sample, compared to > 6 to ≤ 9 h/day of sleep duration, > 9 h/day was associated with 1.70 (95% CI 1.15-2.51) and 1.75 (95% CI 1.08-2.84) times higher odds for sarcopenia and severe sarcopenia, respectively. No significant associations were observed among males, but associations were particularly pronounced among females [i.e., OR = 2.19 (95% CI 1.26-3.81) for sarcopenia, and OR = 2.26 (95% CI 1.20-4.23) for severe sarcopenia].CONCLUSIONS: Long sleep duration was associated with an increased odds of sarcopenia and severe sarcopenia in LMICs, particularly in females. Future studies should investigate whether addressing long sleep duration among females can lead to lower risk for sarcopenia onset in LMICs.

KW - Low- and- middle income countries

KW - Older adults

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KW - Sleep problems

KW - Prevalence

KW - Cross-Sectional Studies

KW - Humans

KW - Male

KW - Sarcopenia/epidemiology

KW - Sleep

KW - Female

KW - Developing Countries

KW - Hand Strength

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DO - 10.1007/s40520-022-02074-3

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