Skeletal Muscle Stem Cells

Elisa Negroni; Maximilien Bencze; Stephanie Duguez; Gillian Butler-Browne; Vincent Mouly

Skeletal Muscle Stem Cells

Elisa Negroni, Maximilien Bencze, Stephanie Duguez, Gillian Butler-Browne, Vincent Mouly

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Stem cell therapy has been envisaged for treating disorders affecting skeletal muscle tissue. The first myogenic stem cell which was proposed and used in clinical trials was the physiological muscle progenitor, i.e. the satellite cell.However, before considering intervention in skeletal muscle, one needs to know well the process of muscle regeneration, as well as the different pathologies that can be eligible for cell therapy. Here, we present an overview of muscle regeneration, the role of satellite cells, how the process is orchestrated,and a short overview on some muscular dystrophies.

Original language	English
Title of host publication	Stem Cell Biology and Regenerative Medicine
Publisher	River Publishers
Pages	415-429
ISBN (Print)	978-1-4614-5492-2
Publication status	Published (in print/issue) - 15 Oct 2014

Keywords

muscle stem cells and regeneration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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AU - Negroni, Elisa

AU - Bencze, Maximilien

AU - Duguez, Stephanie

AU - Butler-Browne, Gillian

AU - Mouly, Vincent

PY - 2014/10/15

Y1 - 2014/10/15

N2 - Stem cell therapy has been envisaged for treating disorders affecting skeletal muscle tissue. The first myogenic stem cell which was proposed and used in clinical trials was the physiological muscle progenitor, i.e. the satellite cell.However, before considering intervention in skeletal muscle, one needs to know well the process of muscle regeneration, as well as the different pathologies that can be eligible for cell therapy. Here, we present an overview of muscle regeneration, the role of satellite cells, how the process is orchestrated,and a short overview on some muscular dystrophies.

AB - Stem cell therapy has been envisaged for treating disorders affecting skeletal muscle tissue. The first myogenic stem cell which was proposed and used in clinical trials was the physiological muscle progenitor, i.e. the satellite cell.However, before considering intervention in skeletal muscle, one needs to know well the process of muscle regeneration, as well as the different pathologies that can be eligible for cell therapy. Here, we present an overview of muscle regeneration, the role of satellite cells, how the process is orchestrated,and a short overview on some muscular dystrophies.

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M3 - Chapter

SN - 978-1-4614-5492-2

SP - 415

EP - 429

BT - Stem Cell Biology and Regenerative Medicine

PB - River Publishers

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Skeletal Muscle Stem Cells

Abstract

Keywords

UN SDGs

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