In this issue of Neuron, Fonkeu et al. (2019) present a mathematical model of mRNA and protein synthesis, degradation, diffusion, and trafficking in neuronal dendrites. The model can predict the spatial distribution and temporal dynamics of proteins along dendrites. The authors use the model to account for in situ imaging data of CaMKII⍺ mRNA and protein in hippocampal neurons.
Bibliographical noteCrown Copyright © 2019. Published by Elsevier Inc. All rights reserved.
- Protein Biosynthesis
- RNA, Messenger