Abstract
BackgroundThe decreasing prevalence of COVID-19 has highlighted the value of vaccinations. CoronaVac® vaccine was one of the most widely used vaccines in Indonesia, in other Southeast Asian countries, as well as in Latin America. However, to date the safety and side effect profiles of CoronaVac® vaccine among the Indonesian population have not been reported.ObjectiveIn this study, the CoronaVac® safety profiles were determined in a community of a public health center in North Jakarta, Indonesia.MethodThis is a descriptive cross-sectional questionnaire-based study on vaccine side effects as recorded in the yellow form (MESO). Patients (n = 300) who received CoronaVac® vaccinations between July and August 2021 were enrolled. SPSS was used to analyze the descriptive data.ResultsMost respondents were women (72.7 %) between the ages of 17 and 21 years. A significantly (p = 0.009) positive correlation was established between the vaccine side effects (namely pain at the injection site) with the female gender. Other side effects such as fatigue (p = 0.034) and headache (p ConclusionOverall, the side effects following the first and the second doses were generally mild and included fever, pain in the injection area, fatigue, headache, drowsiness, diarrhea, cough, and nausea. Regarding vaccine efficacy, CoronaVac® confers better protection following the second dose administration where the percentage of respondents affected with COVID-19 (26.7 %) decreased to only 20.3 % following the second dose.
| Original language | English |
|---|---|
| Article number | e30087 |
| Pages (from-to) | 1-12 |
| Number of pages | 12 |
| Journal | Heliyon |
| Volume | 10 |
| Issue number | 9 |
| Early online date | 26 Apr 2024 |
| DOIs | |
| Publication status | Published online - 26 Apr 2024 |
Bibliographical note
Publisher Copyright:© 2024 The Author(s)
Funding
We would like to acknowledge Ministry of Education and Research Indonesia (Kemenristek Dikti) and Education fund management agency (LPDP Indonesia) for the support under the World Professor Class (WPC) programme, and Universitas 17 Agustus 1945 Jakarta.
| Funders |
|---|
| Universitas 17 Agustus 1945 Jakarta |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Vaccine
- Side effects
- COVID-19
- CoronaVac vaccine
- AEFI
- CoronaVac® vaccine
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