Side effects of CoronaVac® COVID-19 vaccination: Investigation in North Jakarta district public health center communities in Indonesia

Diana Laila Ramatillah, Siew Hua Gan, Judith Novarticia, Gena Nafta Araminda, Michael Michael, Mohammad Elnaem, Rizki Alawuddin, Kashifullah Khan

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
25 Downloads (Pure)

Abstract

BackgroundThe decreasing prevalence of COVID-19 has highlighted the value of vaccinations. CoronaVac® vaccine was one of the most widely used vaccines in Indonesia, in other Southeast Asian countries, as well as in Latin America. However, to date the safety and side effect profiles of CoronaVac® vaccine among the Indonesian population have not been reported.ObjectiveIn this study, the CoronaVac® safety profiles were determined in a community of a public health center in North Jakarta, Indonesia.MethodThis is a descriptive cross-sectional questionnaire-based study on vaccine side effects as recorded in the yellow form (MESO). Patients (n = 300) who received CoronaVac® vaccinations between July and August 2021 were enrolled. SPSS was used to analyze the descriptive data.ResultsMost respondents were women (72.7 %) between the ages of 17 and 21 years. A significantly (p = 0.009) positive correlation was established between the vaccine side effects (namely pain at the injection site) with the female gender. Other side effects such as fatigue (p = 0.034) and headache (p ConclusionOverall, the side effects following the first and the second doses were generally mild and included fever, pain in the injection area, fatigue, headache, drowsiness, diarrhea, cough, and nausea. Regarding vaccine efficacy, CoronaVac® confers better protection following the second dose administration where the percentage of respondents affected with COVID-19 (26.7 %) decreased to only 20.3 % following the second dose.
Original languageEnglish
Article numbere30087
Pages (from-to)1-12
Number of pages12
JournalHeliyon
Volume10
Issue number9
Early online date26 Apr 2024
DOIs
Publication statusPublished online - 26 Apr 2024

Bibliographical note

Publisher Copyright:
© 2024 The Author(s)

Keywords

  • Vaccine
  • Side effects
  • COVID-19
  • CoronaVac vaccine
  • AEFI
  • CoronaVac® vaccine

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