Sex differences in the association between dynapenic abdominal obesity and activities of daily living disability onset among adults aged ≥50 years: a prospective analysis of the Irish Longitudinal Study on Ageing: A prospective analysis of the Irish Longitudinal Study on Ageing

Lee Smith, Guillermo F. López‐Sánchez, Mark Tully, Nicola Veronese, Pinar Soysal, Dong Keon Yon, Damiano Pizzol, José Francisco López-gil, Yvonne Barnett, Laurie Butler, Jae Il Shin, Ai Koyanagi

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Abstract

Background: Sex differences in the longitudinal relationship between dynapenic abdominal obesity, i.e., impairment in muscle strength and high waist circumference, and activities of daily living disability have not been investigated to date. Therefore, we aimed to examine sex differences in the longitudinal association between dynapenic abdominal obesity at baseline
and new onset activities of daily living disability during a four-year follow-up period among Irish adults aged ≥50 years.
Methods: Data from Wave 1 (2009-2011) and Wave 3 (2014-2015) of the Irish Longitudinal Study on Ageing survey were analyzed. Dynapenia was defined as handgrip strength of circumference of >88 cm for women and >102 cm for men. Dynapenic abdominal obesity was defined as having both dynapenia and abdominal obesity. Disability was defined as having difficulty with at least one of six types of activities of daily living (dressing, walking, bathing, eating, getting in or out of bed, using the toilet). Multivariable logistic regression was conducted to assess associations.
Results: Data on 4,471 individuals aged ≥50 years free of disability at baseline were analyzed [mean (SD) age 62.3 (8.6) years; 48.3% males]. In the overall sample, compared to no dynapenia and no abdominal obesity, dynapenic abdominal obesity was associated with 2.15 (95%CI=1.17-3.93) times higher odds for incident disability at 4-year follow-up. This association was significant among males (OR=3.78; 95%CI=1.70-8.38) but not among females (OR=1.34; 95%CI=0.60-2.98).
Conclusions: Interventions to prevent or address DAO may aid in the prevention of disability especially among men.
Original languageEnglish
Article number107763
Pages (from-to)1-7
Number of pages7
JournalMaturitas
Volume176
Early online date22 Jun 2023
DOIs
Publication statusPublished (in print/issue) - 1 Oct 2023

Bibliographical note

Funding Information:
Dr. Guillermo F. López Sánchez is funded by the European Union – Next Generation EU. Dr. José Francisco López-Gil is a Margarita Salas Fellow (Universidad Pública de Navarra – 1225/2022 ).

Funding Information:
Dr. Guillermo F. López Sánchez is funded by the European Union – Next Generation EU. Dr. José Francisco López-Gil is a Margarita Salas Fellow (Universidad Pública de Navarra – 1225/2022).

Publisher Copyright:
© 2023 The Authors

Keywords

  • Dynapenia
  • Abdominal obesity
  • Dynapenic abdominal obesity
  • Middle-aged to older adults
  • Disability
  • Epidemiology
  • Ireland

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