Serum total free-radical trapping ability in acute myocardial-infarction

CW Mulholland, JJ Strain

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p < 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p < 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.
LanguageEnglish
Pages437-441
JournalClinical Biochemistry
Volume24
Issue number5
Publication statusPublished - Oct 1991

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Free Radicals
Myocardial Infarction
alpha-Tocopherol
Serum
Control Groups
Antioxidants
Regression Analysis

Cite this

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title = "Serum total free-radical trapping ability in acute myocardial-infarction",
abstract = "Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p < 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p < 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.",
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month = "10",
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Serum total free-radical trapping ability in acute myocardial-infarction. / Mulholland, CW; Strain, JJ.

In: Clinical Biochemistry, Vol. 24, No. 5, 10.1991, p. 437-441.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Serum total free-radical trapping ability in acute myocardial-infarction

AU - Mulholland, CW

AU - Strain, JJ

PY - 1991/10

Y1 - 1991/10

N2 - Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p < 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p < 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.

AB - Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p < 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p < 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.

M3 - Article

VL - 24

SP - 437

EP - 441

JO - Clinical Biochemistry

T2 - Clinical Biochemistry

JF - Clinical Biochemistry

SN - 0009-9120

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