Serum antioxidant potential, and lipoprotein oxidation in female smokers following vitamin C supplementation

CW Mulholland, JJ Strain, TR Trinick

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A single blind placebo controlled trial was carried out to assess the effect of high dose vitamin C supplementation on the antioxidant potential, and extent of lipoprotein oxidation of serum in female smokers. Sixteen apparently healthy subjects were randomised into two groups of eight. One group received 1 g of vitamin C for 14 days the other group received a placebo for 14 days. Serum antioxidant potential (TRAP) was measured and lipoprotein oxidation was assessed by measuring serum malondialdehyde Like material. Despite significant increases in serum C concentrations in the supplemented group, serum TRAP values did not change significantly over the course of the trial. Serum malondialdehyde like material also failed to show any temporal variation.
Original languageEnglish
Pages (from-to)227-231
JournalInternational Journal of Food Sciences and Nutrition
Issue number3
Publication statusPublished - May 1996


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