Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283

D Turck, J Castenmiller, S De Henauw, K Hirsch‐Ernst, J Kearney, A Maciuk, I Mangelsdorf, H McArdle, A Naska, C Pelaez, K. Pentieva, A Siani, F Thies, S Tsabouri, M Vinceti, F Cubadda, KH Engel, T Frenzel, M Heinonen, R Marchelli & 8 others M Neuhauser-Berthold, A Poting, M Poulsen, Y Sanz, JR Schlatter, H van Loveren, R Ackerl, H Knutsen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on Yarrowia lipolytica yeast biomass as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed biomass of Yarrowia lipolytica, a yeast species that is widespread in nature and which can be found in the environment as well as in foods. The production process is sufficiently described and does not raise safety concerns. The information provided on the composition of the NF is sufficient and does not raise safety concerns. The applicant proposed to use the NF as a food supplement in the form of capsules, tablets or powder. The target population for the NF is the general population above 3 years of age. The maximum proposed daily use levels are 3 g/day for children from 3 years to less than 10 years of age and 6 g/day thereafter. Taking into account the composition of the NF and the proposed use levels, the consumption of the NF is not nutritionally disadvantageous. No relevant toxicological information was provided. The Panel considers that given the qualified presumption of safety (QPS) status for production purposes of Yarrowia lipolytica and the fact that the production process of the NF does not raise safety concerns, no toxicological studies are needed for the safety assessment of the NF. The Panel concludes that the NF, Yarrowia lipolytica yeast biomass, is safe under the proposed conditions of use.
LanguageEnglish
Article numbere05594
Number of pages12
JournalEFSA Journal
Volume17
Issue number2
DOIs
Publication statusPublished - 14 Feb 2019

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Yarrowia
Yarrowia lipolytica
novel foods
Biomass
Yeasts
yeasts
Safety
Food
biomass
Toxicology
Preserved Food
safety assessment
Health Services Needs and Demand
allergens
Dietary Supplements
dietary supplements
Powders
Allergens
Tablets
powders

Keywords

  • Yarrowia lipolytica
  • yeast
  • novel food
  • safety
  • Yeast
  • Novel food
  • Biomass
  • Safety

Cite this

Turck, D., Castenmiller, J., De Henauw, S., Hirsch‐Ernst, K., Kearney, J., Maciuk, A., ... Knutsen, H. (2019). Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283. EFSA Journal, 17(2), [e05594]. https://doi.org/10.2903/j.efsa.2019.5594
Turck, D ; Castenmiller, J ; De Henauw, S ; Hirsch‐Ernst, K ; Kearney, J ; Maciuk, A ; Mangelsdorf, I ; McArdle, H ; Naska, A ; Pelaez, C ; Pentieva, K. ; Siani, A ; Thies, F ; Tsabouri, S ; Vinceti, M ; Cubadda, F ; Engel, KH ; Frenzel, T ; Heinonen, M ; Marchelli, R ; Neuhauser-Berthold, M ; Poting, A ; Poulsen, M ; Sanz, Y ; Schlatter, JR ; van Loveren, H ; Ackerl, R ; Knutsen, H. / Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283. In: EFSA Journal. 2019 ; Vol. 17, No. 2.
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title = "Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283",
abstract = "Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on Yarrowia lipolytica yeast biomass as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed biomass of Yarrowia lipolytica, a yeast species that is widespread in nature and which can be found in the environment as well as in foods. The production process is sufficiently described and does not raise safety concerns. The information provided on the composition of the NF is sufficient and does not raise safety concerns. The applicant proposed to use the NF as a food supplement in the form of capsules, tablets or powder. The target population for the NF is the general population above 3 years of age. The maximum proposed daily use levels are 3 g/day for children from 3 years to less than 10 years of age and 6 g/day thereafter. Taking into account the composition of the NF and the proposed use levels, the consumption of the NF is not nutritionally disadvantageous. No relevant toxicological information was provided. The Panel considers that given the qualified presumption of safety (QPS) status for production purposes of Yarrowia lipolytica and the fact that the production process of the NF does not raise safety concerns, no toxicological studies are needed for the safety assessment of the NF. The Panel concludes that the NF, Yarrowia lipolytica yeast biomass, is safe under the proposed conditions of use.",
keywords = "Yarrowia lipolytica, yeast, novel food, safety, Yeast, Novel food, Biomass, Safety",
author = "D Turck and J Castenmiller and {De Henauw}, S and K Hirsch‐Ernst and J Kearney and A Maciuk and I Mangelsdorf and H McArdle and A Naska and C Pelaez and K. Pentieva and A Siani and F Thies and S Tsabouri and M Vinceti and F Cubadda and KH Engel and T Frenzel and M Heinonen and R Marchelli and M Neuhauser-Berthold and A Poting and M Poulsen and Y Sanz and JR Schlatter and {van Loveren}, H and R Ackerl and H Knutsen",
note = "The accepted date is know as the Adopted date with this article - The adopted date is listed on the author manuscript.",
year = "2019",
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language = "English",
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Turck, D, Castenmiller, J, De Henauw, S, Hirsch‐Ernst, K, Kearney, J, Maciuk, A, Mangelsdorf, I, McArdle, H, Naska, A, Pelaez, C, Pentieva, K, Siani, A, Thies, F, Tsabouri, S, Vinceti, M, Cubadda, F, Engel, KH, Frenzel, T, Heinonen, M, Marchelli, R, Neuhauser-Berthold, M, Poting, A, Poulsen, M, Sanz, Y, Schlatter, JR, van Loveren, H, Ackerl, R & Knutsen, H 2019, 'Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283', EFSA Journal, vol. 17, no. 2, e05594. https://doi.org/10.2903/j.efsa.2019.5594

Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283. / Turck, D; Castenmiller, J; De Henauw, S; Hirsch‐Ernst, K; Kearney, J; Maciuk, A; Mangelsdorf, I; McArdle, H; Naska, A; Pelaez, C; Pentieva, K.; Siani, A; Thies, F; Tsabouri, S; Vinceti, M; Cubadda, F; Engel, KH; Frenzel, T; Heinonen, M; Marchelli, R; Neuhauser-Berthold, M; Poting, A; Poulsen, M; Sanz, Y; Schlatter, JR; van Loveren, H; Ackerl, R; Knutsen, H.

In: EFSA Journal, Vol. 17, No. 2, e05594, 14.02.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283

AU - Turck, D

AU - Castenmiller, J

AU - De Henauw, S

AU - Hirsch‐Ernst, K

AU - Kearney, J

AU - Maciuk, A

AU - Mangelsdorf, I

AU - McArdle, H

AU - Naska, A

AU - Pelaez, C

AU - Pentieva, K.

AU - Siani, A

AU - Thies, F

AU - Tsabouri, S

AU - Vinceti, M

AU - Cubadda, F

AU - Engel, KH

AU - Frenzel, T

AU - Heinonen, M

AU - Marchelli, R

AU - Neuhauser-Berthold, M

AU - Poting, A

AU - Poulsen, M

AU - Sanz, Y

AU - Schlatter, JR

AU - van Loveren, H

AU - Ackerl, R

AU - Knutsen, H

N1 - The accepted date is know as the Adopted date with this article - The adopted date is listed on the author manuscript.

PY - 2019/2/14

Y1 - 2019/2/14

N2 - Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on Yarrowia lipolytica yeast biomass as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed biomass of Yarrowia lipolytica, a yeast species that is widespread in nature and which can be found in the environment as well as in foods. The production process is sufficiently described and does not raise safety concerns. The information provided on the composition of the NF is sufficient and does not raise safety concerns. The applicant proposed to use the NF as a food supplement in the form of capsules, tablets or powder. The target population for the NF is the general population above 3 years of age. The maximum proposed daily use levels are 3 g/day for children from 3 years to less than 10 years of age and 6 g/day thereafter. Taking into account the composition of the NF and the proposed use levels, the consumption of the NF is not nutritionally disadvantageous. No relevant toxicological information was provided. The Panel considers that given the qualified presumption of safety (QPS) status for production purposes of Yarrowia lipolytica and the fact that the production process of the NF does not raise safety concerns, no toxicological studies are needed for the safety assessment of the NF. The Panel concludes that the NF, Yarrowia lipolytica yeast biomass, is safe under the proposed conditions of use.

AB - Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on Yarrowia lipolytica yeast biomass as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is the dried and heat‐killed biomass of Yarrowia lipolytica, a yeast species that is widespread in nature and which can be found in the environment as well as in foods. The production process is sufficiently described and does not raise safety concerns. The information provided on the composition of the NF is sufficient and does not raise safety concerns. The applicant proposed to use the NF as a food supplement in the form of capsules, tablets or powder. The target population for the NF is the general population above 3 years of age. The maximum proposed daily use levels are 3 g/day for children from 3 years to less than 10 years of age and 6 g/day thereafter. Taking into account the composition of the NF and the proposed use levels, the consumption of the NF is not nutritionally disadvantageous. No relevant toxicological information was provided. The Panel considers that given the qualified presumption of safety (QPS) status for production purposes of Yarrowia lipolytica and the fact that the production process of the NF does not raise safety concerns, no toxicological studies are needed for the safety assessment of the NF. The Panel concludes that the NF, Yarrowia lipolytica yeast biomass, is safe under the proposed conditions of use.

KW - Yarrowia lipolytica

KW - yeast

KW - novel food

KW - safety

KW - Yeast

KW - Novel food

KW - Biomass

KW - Safety

U2 - 10.2903/j.efsa.2019.5594

DO - 10.2903/j.efsa.2019.5594

M3 - Article

VL - 17

JO - EFSA Journal

T2 - EFSA Journal

JF - EFSA Journal

SN - 1831-4732

IS - 2

M1 - e05594

ER -

Turck D, Castenmiller J, De Henauw S, Hirsch‐Ernst K, Kearney J, Maciuk A et al. Safety of Yarrowia lipolytica yeast biomass as a novel food pursuant to Regulation (EU) 2015/2283. EFSA Journal. 2019 Feb 14;17(2). e05594. https://doi.org/10.2903/j.efsa.2019.5594