Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews

Joseph Hibbeln, Philip Spiller, Thomas Brenna, Jean Golding, Bruce Holub, William Harris, Penny Kris-Etherton, Bill Lands, Sonja Connor, Gary Myers, Sean Strain, Michael Crawford, Susan Carlson

Research output: Contribution to journalReview article

Abstract

Abundant data are now available to evaluate relationships between seafood consumption in pregnancy and childhood and neurocognitive development. We conducted two systematic reviews utilizing methodologies detailed by the Dietary Guidelines for Americans Scientific Advisory Committee 2020–2025. After reviewing 44 publications on 106,237 mother-offspring pairs and 25,960 children, our technical expert committee developed two conclusion statements that included the following: “Moderate and consistent evidence indicates that consumption of a wide range of amounts and types of commercially available seafood during pregnancy is associated with improved neurocognitive development of offspring as compared to eating no seafood. Overall, benefits to neurocognitive development began at the lowest amounts of seafood consumed (∼4 oz/wk) and continued through the highest amounts, above 12 oz/wk, some range up to>100 oz/wk.”, “This evidence does not meet the criteria for “strong evidence” only due to a paucity of randomized controlled trials that may not be ethical or feasible to conduct for pregnancy” and “Moderate and consistent evidence indicates that consumption of>4 oz/wk and likely>12 oz/wk of seafood during childhood has beneficial associations with neurocognitive outcomes.” No net adverse neurocognitive outcomes were reported among offspring at the highest ranges of seafood intakes despite associated increases in mercury exposures. Data are insufficient for conclusive statements regarding lactation, optimal amounts, categories or specific species characterized by mercury content and neurocognitive development; although there is some evidence that dark/oily seafood may be more beneficial. Research was conducted in healthy women and children and is generalizable to US populations. Assessment of seafood as a whole food integrates inherently integrates any adverse effects from neurotoxicants, if any, and benefits to neurocognition from omega-3 fats, as well as other nutrients critical
Original languageEnglish
Pages (from-to)14-36
Number of pages23
JournalProstaglandins, Leukotrienes and Essential Fatty Acids
Volume151
Early online date11 Oct 2019
DOIs
Publication statusPublished - 31 Dec 2019

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Seafood
Mercury
Pregnancy
Nutrients
Fats
Food
Nutrition Policy
Advisory Committees
Lactation
Publications
Randomized Controlled Trials
Eating
Mothers

Cite this

Hibbeln, Joseph ; Spiller, Philip ; Brenna, Thomas ; Golding, Jean ; Holub, Bruce ; Harris, William ; Kris-Etherton, Penny ; Lands, Bill ; Connor, Sonja ; Myers, Gary ; Strain, Sean ; Crawford, Michael ; Carlson, Susan. / Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews. In: Prostaglandins, Leukotrienes and Essential Fatty Acids. 2019 ; Vol. 151. pp. 14-36.
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abstract = "Abundant data are now available to evaluate relationships between seafood consumption in pregnancy and childhood and neurocognitive development. We conducted two systematic reviews utilizing methodologies detailed by the Dietary Guidelines for Americans Scientific Advisory Committee 2020–2025. After reviewing 44 publications on 106,237 mother-offspring pairs and 25,960 children, our technical expert committee developed two conclusion statements that included the following: “Moderate and consistent evidence indicates that consumption of a wide range of amounts and types of commercially available seafood during pregnancy is associated with improved neurocognitive development of offspring as compared to eating no seafood. Overall, benefits to neurocognitive development began at the lowest amounts of seafood consumed (∼4 oz/wk) and continued through the highest amounts, above 12 oz/wk, some range up to>100 oz/wk.”, “This evidence does not meet the criteria for “strong evidence” only due to a paucity of randomized controlled trials that may not be ethical or feasible to conduct for pregnancy” and “Moderate and consistent evidence indicates that consumption of>4 oz/wk and likely>12 oz/wk of seafood during childhood has beneficial associations with neurocognitive outcomes.” No net adverse neurocognitive outcomes were reported among offspring at the highest ranges of seafood intakes despite associated increases in mercury exposures. Data are insufficient for conclusive statements regarding lactation, optimal amounts, categories or specific species characterized by mercury content and neurocognitive development; although there is some evidence that dark/oily seafood may be more beneficial. Research was conducted in healthy women and children and is generalizable to US populations. Assessment of seafood as a whole food integrates inherently integrates any adverse effects from neurotoxicants, if any, and benefits to neurocognition from omega-3 fats, as well as other nutrients critical",
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Hibbeln, J, Spiller, P, Brenna, T, Golding, J, Holub, B, Harris, W, Kris-Etherton, P, Lands, B, Connor, S, Myers, G, Strain, S, Crawford, M & Carlson, S 2019, 'Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews', Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 151, pp. 14-36. https://doi.org/10.1016/j.plefa.2019.10.002

Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews. / Hibbeln, Joseph; Spiller, Philip; Brenna, Thomas; Golding, Jean; Holub, Bruce; Harris, William; Kris-Etherton, Penny; Lands, Bill; Connor, Sonja; Myers, Gary; Strain, Sean; Crawford, Michael; Carlson, Susan.

In: Prostaglandins, Leukotrienes and Essential Fatty Acids, Vol. 151, 31.12.2019, p. 14-36.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Relationships between seafood consumption during pregnancy and childhood and neurocognitive development: Two systematic reviews

AU - Hibbeln, Joseph

AU - Spiller, Philip

AU - Brenna, Thomas

AU - Golding, Jean

AU - Holub, Bruce

AU - Harris, William

AU - Kris-Etherton, Penny

AU - Lands, Bill

AU - Connor, Sonja

AU - Myers, Gary

AU - Strain, Sean

AU - Crawford, Michael

AU - Carlson, Susan

PY - 2019/12/31

Y1 - 2019/12/31

N2 - Abundant data are now available to evaluate relationships between seafood consumption in pregnancy and childhood and neurocognitive development. We conducted two systematic reviews utilizing methodologies detailed by the Dietary Guidelines for Americans Scientific Advisory Committee 2020–2025. After reviewing 44 publications on 106,237 mother-offspring pairs and 25,960 children, our technical expert committee developed two conclusion statements that included the following: “Moderate and consistent evidence indicates that consumption of a wide range of amounts and types of commercially available seafood during pregnancy is associated with improved neurocognitive development of offspring as compared to eating no seafood. Overall, benefits to neurocognitive development began at the lowest amounts of seafood consumed (∼4 oz/wk) and continued through the highest amounts, above 12 oz/wk, some range up to>100 oz/wk.”, “This evidence does not meet the criteria for “strong evidence” only due to a paucity of randomized controlled trials that may not be ethical or feasible to conduct for pregnancy” and “Moderate and consistent evidence indicates that consumption of>4 oz/wk and likely>12 oz/wk of seafood during childhood has beneficial associations with neurocognitive outcomes.” No net adverse neurocognitive outcomes were reported among offspring at the highest ranges of seafood intakes despite associated increases in mercury exposures. Data are insufficient for conclusive statements regarding lactation, optimal amounts, categories or specific species characterized by mercury content and neurocognitive development; although there is some evidence that dark/oily seafood may be more beneficial. Research was conducted in healthy women and children and is generalizable to US populations. Assessment of seafood as a whole food integrates inherently integrates any adverse effects from neurotoxicants, if any, and benefits to neurocognition from omega-3 fats, as well as other nutrients critical

AB - Abundant data are now available to evaluate relationships between seafood consumption in pregnancy and childhood and neurocognitive development. We conducted two systematic reviews utilizing methodologies detailed by the Dietary Guidelines for Americans Scientific Advisory Committee 2020–2025. After reviewing 44 publications on 106,237 mother-offspring pairs and 25,960 children, our technical expert committee developed two conclusion statements that included the following: “Moderate and consistent evidence indicates that consumption of a wide range of amounts and types of commercially available seafood during pregnancy is associated with improved neurocognitive development of offspring as compared to eating no seafood. Overall, benefits to neurocognitive development began at the lowest amounts of seafood consumed (∼4 oz/wk) and continued through the highest amounts, above 12 oz/wk, some range up to>100 oz/wk.”, “This evidence does not meet the criteria for “strong evidence” only due to a paucity of randomized controlled trials that may not be ethical or feasible to conduct for pregnancy” and “Moderate and consistent evidence indicates that consumption of>4 oz/wk and likely>12 oz/wk of seafood during childhood has beneficial associations with neurocognitive outcomes.” No net adverse neurocognitive outcomes were reported among offspring at the highest ranges of seafood intakes despite associated increases in mercury exposures. Data are insufficient for conclusive statements regarding lactation, optimal amounts, categories or specific species characterized by mercury content and neurocognitive development; although there is some evidence that dark/oily seafood may be more beneficial. Research was conducted in healthy women and children and is generalizable to US populations. Assessment of seafood as a whole food integrates inherently integrates any adverse effects from neurotoxicants, if any, and benefits to neurocognition from omega-3 fats, as well as other nutrients critical

U2 - 10.1016/j.plefa.2019.10.002

DO - 10.1016/j.plefa.2019.10.002

M3 - Review article

VL - 151

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JO - Prostaglandins, Leukotrienes and Essential Fatty Acids

JF - Prostaglandins, Leukotrienes and Essential Fatty Acids

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