Regulation and feedback of cholesterol metabolism

Steven Watterson

    Research output: Non-textual form › Web publication/site

    Abstract

    Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.
    LanguageEnglish
    DOIs
    Publication statusPublished - 31 Aug 2011

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    Cholesterol
    Biological Phenomena
    Systems Biology
    Health
    Research

    Keywords

    • SREBP-2
    • LXR
    • SBGN PD
    • cholesterol metabolism
    • 25-hydroxycholesterol
    • network reconstruction
    • regulation
    • prenylation
    • dolichol synthesis
    • SBGN

    Cite this

    Watterson, Steven (Author). / Regulation and feedback of cholesterol metabolism. [Web publication/site].
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    title = "Regulation and feedback of cholesterol metabolism",
    abstract = "Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.",
    keywords = "SREBP-2, LXR, SBGN PD, cholesterol metabolism, 25-hydroxycholesterol, network reconstruction, regulation, prenylation, dolichol synthesis, SBGN",
    author = "Steven Watterson",
    year = "2011",
    month = "8",
    day = "31",
    doi = "10.1038/npre.2011.6315.1",
    language = "English",

    }

    Watterson, S, Regulation and feedback of cholesterol metabolism, 2011, Web publication/site. https://doi.org/10.1038/npre.2011.6315.1
    Regulation and feedback of cholesterol metabolism. Watterson, Steven (Author). 2011.

    Research output: Non-textual form › Web publication/site

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    PY - 2011/8/31

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    N2 - Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.

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    KW - SREBP-2

    KW - LXR

    KW - SBGN PD

    KW - cholesterol metabolism

    KW - 25-hydroxycholesterol

    KW - network reconstruction

    KW - regulation

    KW - prenylation

    KW - dolichol synthesis

    KW - SBGN

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    Watterson S (Author). Regulation and feedback of cholesterol metabolism 2011. https://doi.org/10.1038/npre.2011.6315.1

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