Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.
|Publication status||Published - 31 Aug 2011|
- SBGN PD
- cholesterol metabolism
- network reconstruction
- dolichol synthesis