Regulation and feedback of cholesterol metabolism

    Research output: Non-textual formWeb publication/site

    Abstract

    Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.
    LanguageEnglish
    DOIs
    Publication statusPublished - 31 Aug 2011

    Fingerprint

    Cholesterol
    Biological Phenomena
    Systems Biology
    Health
    Research

    Keywords

    • SREBP-2
    • LXR
    • SBGN PD
    • cholesterol metabolism
    • 25-hydroxycholesterol
    • network reconstruction
    • regulation
    • prenylation
    • dolichol synthesis
    • SBGN

    Cite this

    @misc{30f242ef86f6404cb28da720f3fc5a93,
    title = "Regulation and feedback of cholesterol metabolism",
    abstract = "Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.",
    keywords = "SREBP-2, LXR, SBGN PD, cholesterol metabolism, 25-hydroxycholesterol, network reconstruction, regulation, prenylation, dolichol synthesis, SBGN",
    author = "Steven Watterson",
    year = "2011",
    month = "8",
    day = "31",
    doi = "10.1038/npre.2011.6315.1",
    language = "English",

    }

    Regulation and feedback of cholesterol metabolism. Watterson, Steven (Author). 2011.

    Research output: Non-textual formWeb publication/site

    TY - ADVS

    T1 - Regulation and feedback of cholesterol metabolism

    AU - Watterson, Steven

    PY - 2011/8/31

    Y1 - 2011/8/31

    N2 - Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.

    AB - Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.

    KW - SREBP-2

    KW - LXR

    KW - SBGN PD

    KW - cholesterol metabolism

    KW - 25-hydroxycholesterol

    KW - network reconstruction

    KW - regulation

    KW - prenylation

    KW - dolichol synthesis

    KW - SBGN

    U2 - 10.1038/npre.2011.6315.1

    DO - 10.1038/npre.2011.6315.1

    M3 - Web publication/site

    ER -