@inbook{add4eb784f2245e19dfaff6cec2aecec,
title = "Recording the activity of ATP-sensitive K+ channels in open-cell cell-attached configuration",
abstract = "The functional activity of ion channels is affected by their local environment, and for certain types of channels this local effect is critical. This chapter describes a method of recording the activity of ATP-sensitive K+ channels, expressed on the plasma membrane of pancreatic β-cells, without destroying the β-cell architecture. In the open-cell cell-attached patch-clamp configuration, ligands and effectors of these metabolism-dependent channels are delivered to their cytoplasmic side via pores in the plasma membrane produced by bacterial toxins.",
keywords = "ATP-sensitive K channels, Bacterial toxins, Membrane permeabilisation, Open-cell cell-attached configuration, Patch-clamp",
author = "Tarasov, {Andrei I.}",
year = "2008",
month = dec,
day = "1",
doi = "10.1007/978-1-59745-526-8-12",
language = "English",
isbn = "9781934115657",
series = "Methods in Molecular Biology",
pages = "151--164",
editor = "Lippiat, {Jonathan D.}",
booktitle = "Potassium Channels",
}