The superior longitudinal fasciculus (SLF) is a large white matter tract connecting the parietal and frontal lobes, and is comprised of three branches. It is thought to play a crucial role in visuospatial attention and working memory. The recent development of spherical deconvolution-based tractography methods has enabled the complete reconstruction of the three branches of the SLF using diffusion imaging , however to date there have been no such studies in older adults or mild cognitive impairment (MCI). In the current study we sought to perform tractography of the SLF I, II and III in a cohort of older healthy adults and older adults with MCI using constrained spherical deconvolution (CSD)-based tractography, and to relate tract metrics to performance on neurocognitive tests.
|Title of host publication||Unknown Host Publication|
|Publisher||International Society for Magnetic Resonance in Medicine|
|Number of pages||1|
|Publication status||Published - 2013|
|Event||ISMRM Workshop on Diffusion as a Probe of Neural Tissue Microstructure - Croatia|
Duration: 1 Jan 2013 → …
|Workshop||ISMRM Workshop on Diffusion as a Probe of Neural Tissue Microstructure|
|Period||1/01/13 → …|
Kehoe, E. G., Li, X., McGinnity, M., Lawlor, B., Kenny, R. A., Coyle, D., & Bokde, A. L. W. (2013). Reconstruction of the superior longitudinal fasciculus in a cohort of older healthy adults and those with mild cognitive impairment using CSD-based tractography. In Unknown Host Publication International Society for Magnetic Resonance in Medicine.