Questions concerning the proximal origin of SARS‐CoV‐2

Murat Seyran; Damiano Pizzol; Parise Adadi; Tarek Mohamed Abd El‐aziz; Sk. Sarif Hassan; Antonio Soares; Ramesh Kandimalla; Kenneth Lundstrom; Murtaza Tambuwala; Alaa A. A. Aljabali; Amos Lal; Gajendra Kumar Azad; Pabitra Pal Choudhury; Vladimir N. Uversky; Samendra P. Sherchan; Bruce D. Uhal; Nima Rezaei; Adam M. Brufsky

doi:10.1002/jmv.26478

Questions concerning the proximal origin of SARS‐CoV‐2

Murat Seyran, Damiano Pizzol, Parise Adadi, Tarek Mohamed Abd El‐aziz, Sk. Sarif Hassan, Antonio Soares, Ramesh Kandimalla, Kenneth Lundstrom, Murtaza Tambuwala, Alaa A. A. Aljabali, Amos Lal, Gajendra Kumar Azad, Pabitra Pal Choudhury, Vladimir N. Uversky, Samendra P. Sherchan, Bruce D. Uhal, Nima Rezaei, Adam M. Brufsky

School of Pharm. & Pharmaceut. Sc.

Research output: Contribution to journal › Letter › peer-review

3 Citations (Scopus)

21 Downloads (Pure)

Abstract

There is a consensus that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) originated naturally from Bat coronaviruses (CoVs), in particular RaTG13. However, the SARS‐CoV‐2 host tropism/adaptation pattern has significant discrepancies compared to other CoVs, raising questions concerning the proximal origin of SARS‐CoV‐2.

Original language	English
Pages (from-to)	1204-1206
Number of pages	3
Journal	Journal of Medical Virology
Volume	93
Issue number	3
Early online date	3 Sep 2020
DOIs	https://doi.org/10.1002/jmv.26478
Publication status	E-pub ahead of print - 3 Sep 2020

Keywords

coronavirus
fusion protein
genetic variability
mutation

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10.1002/jmv.26478

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Seyran, M., Pizzol, D., Adadi, P., El‐aziz, T. M. A., Hassan, S. S., Soares, A., Kandimalla, R., Lundstrom, K., Tambuwala, M., Aljabali, A. A. A., Lal, A., Azad, G. K., Choudhury, P. P., Uversky, V. N., Sherchan, S. P., Uhal, B. D., Rezaei, N., & Brufsky, A. M. (2021). Questions concerning the proximal origin of SARS‐CoV‐2. Journal of Medical Virology, 93(3), 1204-1206. https://doi.org/10.1002/jmv.26478

Seyran, Murat ; Pizzol, Damiano ; Adadi, Parise ; El‐aziz, Tarek Mohamed Abd ; Hassan, Sk. Sarif ; Soares, Antonio ; Kandimalla, Ramesh ; Lundstrom, Kenneth ; Tambuwala, Murtaza ; Aljabali, Alaa A. A. ; Lal, Amos ; Azad, Gajendra Kumar ; Choudhury, Pabitra Pal ; Uversky, Vladimir N. ; Sherchan, Samendra P. ; Uhal, Bruce D. ; Rezaei, Nima ; Brufsky, Adam M. / Questions concerning the proximal origin of SARS‐CoV‐2. In: Journal of Medical Virology. 2021 ; Vol. 93, No. 3. pp. 1204-1206.

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abstract = "There is a consensus that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) originated naturally from Bat coronaviruses (CoVs), in particular RaTG13. However, the SARS‐CoV‐2 host tropism/adaptation pattern has significant discrepancies compared to other CoVs, raising questions concerning the proximal origin of SARS‐CoV‐2.",

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author = "Murat Seyran and Damiano Pizzol and Parise Adadi and El‐aziz, {Tarek Mohamed Abd} and Hassan, {Sk. Sarif} and Antonio Soares and Ramesh Kandimalla and Kenneth Lundstrom and Murtaza Tambuwala and Aljabali, {Alaa A. A.} and Amos Lal and Azad, {Gajendra Kumar} and Choudhury, {Pabitra Pal} and Uversky, {Vladimir N.} and Sherchan, {Samendra P.} and Uhal, {Bruce D.} and Nima Rezaei and Brufsky, {Adam M.}",

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doi = "10.1002/jmv.26478",

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Seyran, M, Pizzol, D, Adadi, P, El‐aziz, TMA, Hassan, SS, Soares, A, Kandimalla, R, Lundstrom, K, Tambuwala, M, Aljabali, AAA, Lal, A, Azad, GK, Choudhury, PP, Uversky, VN, Sherchan, SP, Uhal, BD, Rezaei, N & Brufsky, AM 2021, 'Questions concerning the proximal origin of SARS‐CoV‐2', Journal of Medical Virology, vol. 93, no. 3, pp. 1204-1206. https://doi.org/10.1002/jmv.26478

Questions concerning the proximal origin of SARS‐CoV‐2. / Seyran, Murat; Pizzol, Damiano; Adadi, Parise; El‐aziz, Tarek Mohamed Abd; Hassan, Sk. Sarif; Soares, Antonio; Kandimalla, Ramesh; Lundstrom, Kenneth; Tambuwala, Murtaza; Aljabali, Alaa A. A.; Lal, Amos; Azad, Gajendra Kumar; Choudhury, Pabitra Pal; Uversky, Vladimir N.; Sherchan, Samendra P.; Uhal, Bruce D.; Rezaei, Nima; Brufsky, Adam M.

In: Journal of Medical Virology, Vol. 93, No. 3, 31.03.2021, p. 1204-1206.

Research output: Contribution to journal › Letter › peer-review

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AU - Pizzol, Damiano

AU - Adadi, Parise

AU - El‐aziz, Tarek Mohamed Abd

AU - Hassan, Sk. Sarif

AU - Soares, Antonio

AU - Kandimalla, Ramesh

AU - Lundstrom, Kenneth

AU - Tambuwala, Murtaza

AU - Aljabali, Alaa A. A.

AU - Lal, Amos

AU - Azad, Gajendra Kumar

AU - Choudhury, Pabitra Pal

AU - Uversky, Vladimir N.

AU - Sherchan, Samendra P.

AU - Uhal, Bruce D.

AU - Rezaei, Nima

AU - Brufsky, Adam M.

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KW - fusion protein

KW - genetic variability

KW - mutation

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