Progress in wound-healing products based on natural compounds, stem cells, and microRNA-based biopolymers in the european, USA, and asian markets: opportunities, barriers, and regulatory Issues

Girish Kumar Srivastava, Sofia Martinez-Rodriguez, Nur Izzah Md Fadilah, Daniel Looi Qi Hao, Gavin Markey, Priyank Shukla, Mh Busra Fauzi, Fivos Panetsos

Research output: Contribution to journalReview articlepeer-review

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Abstract

Wounds are breaks in the continuity of the skin and underlying tissues, resulting from external causes such as cuts, blows, impacts, or surgical interventions. Countless individuals suffer minor to severe injuries, with unfortunate cases even leading to death. In today’s scenario, several commercial products are available to facilitate the healing process of wounds, although chronic wounds still present more challenges than acute wounds. Nevertheless, the huge demand for wound-care products within the healthcare sector has given rise to a rapidly growing market, fostering continuous research and development endeavors for innovative wound-healing solutions. Today, there are many commercially available products including those based on natural biopolymers, stem cells, and microRNAs that promote healing from wounds. This article explores the recent breakthroughs in wound-healing products that harness the potential of natural biopolymers, stem cells, and microRNAs. A comprehensive exploration is undertaken, covering not only commercially available products but also those still in the research phase. Additionally, we provide a thorough examination of the opportunities, obstacles, and regulatory considerations influencing the potential commercialization of wound-healing products across the diverse markets of Europe, America, and Asia.
Original languageEnglish
Article number1280
JournalPolymers
Volume16
Issue number9
Early online date3 May 2024
DOIs
Publication statusPublished online - 3 May 2024

Bibliographical note

Publisher Copyright:
© 2024 by the authors.

Keywords

  • skin injuries
  • therapy
  • caring
  • natural materials
  • regulatory issues
  • ISO

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