Prevalence of carriage of antimicrobial resistant strains of Streptococcus pneumoniae in primary school children in Hong Kong

MV Boost, MM O'Donoghue, JSG Dooley

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A cross-sectional survey was conducted to determine prevalence and assess risk factors for carriage of antibiotic resistant strains of Streptococcus pneumoniae in healthy school children in Hong Kong. Throat swabs were collected from 1455 subjects and written questionnaires providing demographic data and medical history were completed by parents. The overall carriage rate of Streptococcus pneumoniae was 3.5 %, of which 49 % were penicillin resistant. High levels of resistance to tetracycline (73 %), erythromycin (52 %), trimethoprim. (66 %) and ciprofloxacin (57 %) were observed. Carriage was associated with presence of a younger sibling (OR = 1.79) and use of antibiotics (OR = 2.31). High use of day care and small size of housing units did not result in a high rate of carriage. The low rate of carriage may be linked to high use of antibiotics, geographical factors or ethnicity. High rates of antibiotic resistance reflect heavy use of antibiotics by general practitioners.
LanguageEnglish
Pages49-55
JournalEpidemiology and Infection
Volume127
Issue number1
Publication statusPublished - Aug 2001

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Hong Kong
Streptococcus pneumoniae
Anti-Bacterial Agents
Tetracycline Resistance
Trimethoprim
Erythromycin
Ciprofloxacin
Microbial Drug Resistance
Pharynx
Penicillins
General Practitioners
Siblings
Cross-Sectional Studies
Parents
Demography

Cite this

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title = "Prevalence of carriage of antimicrobial resistant strains of Streptococcus pneumoniae in primary school children in Hong Kong",
abstract = "A cross-sectional survey was conducted to determine prevalence and assess risk factors for carriage of antibiotic resistant strains of Streptococcus pneumoniae in healthy school children in Hong Kong. Throat swabs were collected from 1455 subjects and written questionnaires providing demographic data and medical history were completed by parents. The overall carriage rate of Streptococcus pneumoniae was 3.5 {\%}, of which 49 {\%} were penicillin resistant. High levels of resistance to tetracycline (73 {\%}), erythromycin (52 {\%}), trimethoprim. (66 {\%}) and ciprofloxacin (57 {\%}) were observed. Carriage was associated with presence of a younger sibling (OR = 1.79) and use of antibiotics (OR = 2.31). High use of day care and small size of housing units did not result in a high rate of carriage. The low rate of carriage may be linked to high use of antibiotics, geographical factors or ethnicity. High rates of antibiotic resistance reflect heavy use of antibiotics by general practitioners.",
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Prevalence of carriage of antimicrobial resistant strains of Streptococcus pneumoniae in primary school children in Hong Kong. / Boost, MV; O'Donoghue, MM; Dooley, JSG.

In: Epidemiology and Infection, Vol. 127, No. 1, 08.2001, p. 49-55.

Research output: Contribution to journalArticle

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