Prevalence and sociodemographic patterns of antidepressant use among women of reproductive age: a prescription database study.

Helen Dolk, Anthony Wemakor, K. Casson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

BACKGROUND:
There has been a steady increase in the prescription of antidepressants in developed countries in recent decades. Antidepressant treatment prevalence and sociodemographic pattern data can inform the review of clinical guidelines for depression treatment. We determined the one-year prevalence and sociodemographic pattern of antidepressant dispensing among women of childbearing age (15-45 years) in Northern Ireland (NI).

METHODS:
A cross-sectional study using individual electronic prescribing data for 2009. Our study population was 268,917 women of childbearing age (15-45 years), with/without prescriptions, registered with the 246 out of 363GP practices in NI with high electronic prescribing data coverage. Socioeconomic deprivation (in quintiles) was measured by an area indicator attached to residential postcode.

RESULTS:
The one-year prevalence of redeemed antidepressant prescriptions was 16.3% (95% CI 16.1-16.4). More than two-thirds of antidepressant prescriptions were for SSRIs. Thirty-five per cent of the women who redeemed prescriptions for antidepressants also redeemed prescriptions for psycholeptics within 2 months of the antidepressant prescriptions. Redeemed antidepressant prescription prevalence increased from 4.8% (15-19 years) to 24.6% (40-45 years), from 13.5% (quintile 1, least deprived) to 20.7% (quintile 5, most deprived), and with urbanity of GP practice location.

LIMITATION:
Only GP practices with high capture of electronic prescribing data were included, which may not be entirely representative of NI. We could not assess the appropriateness of prescribing according to national guidelines.

CONCLUSIONS:
Antidepressant use is high among women of childbearing age in NI and increases with age and socioeconomic deprivation. This reinforces the need to address the determinants of depression, and assess the appropriateness of treatment policies and practices.
LanguageEnglish
Pages299-305
JournalJournal of Affective Disorders
Volume167
DOIs
Publication statusPublished - 19 Jun 2014

Fingerprint

Antidepressive Agents
Prescriptions
Databases
Northern Ireland
Electronic Prescribing
Guidelines
Developed Countries
Therapeutics
Cross-Sectional Studies
Population

Keywords

  • Age
  • Antidepressants
  • Socioeconomic deprivation
  • Women of childbearing age

Cite this

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title = "Prevalence and sociodemographic patterns of antidepressant use among women of reproductive age: a prescription database study.",
abstract = "BACKGROUND:There has been a steady increase in the prescription of antidepressants in developed countries in recent decades. Antidepressant treatment prevalence and sociodemographic pattern data can inform the review of clinical guidelines for depression treatment. We determined the one-year prevalence and sociodemographic pattern of antidepressant dispensing among women of childbearing age (15-45 years) in Northern Ireland (NI).METHODS:A cross-sectional study using individual electronic prescribing data for 2009. Our study population was 268,917 women of childbearing age (15-45 years), with/without prescriptions, registered with the 246 out of 363GP practices in NI with high electronic prescribing data coverage. Socioeconomic deprivation (in quintiles) was measured by an area indicator attached to residential postcode.RESULTS:The one-year prevalence of redeemed antidepressant prescriptions was 16.3{\%} (95{\%} CI 16.1-16.4). More than two-thirds of antidepressant prescriptions were for SSRIs. Thirty-five per cent of the women who redeemed prescriptions for antidepressants also redeemed prescriptions for psycholeptics within 2 months of the antidepressant prescriptions. Redeemed antidepressant prescription prevalence increased from 4.8{\%} (15-19 years) to 24.6{\%} (40-45 years), from 13.5{\%} (quintile 1, least deprived) to 20.7{\%} (quintile 5, most deprived), and with urbanity of GP practice location.LIMITATION:Only GP practices with high capture of electronic prescribing data were included, which may not be entirely representative of NI. We could not assess the appropriateness of prescribing according to national guidelines.CONCLUSIONS:Antidepressant use is high among women of childbearing age in NI and increases with age and socioeconomic deprivation. This reinforces the need to address the determinants of depression, and assess the appropriateness of treatment policies and practices.",
keywords = "Age, Antidepressants, Socioeconomic deprivation, Women of childbearing age",
author = "Helen Dolk and Anthony Wemakor and K. Casson",
year = "2014",
month = "6",
day = "19",
doi = "10.1016/j.jad.2014.06.015",
language = "English",
volume = "167",
pages = "299--305",
journal = "Journal of Affective Disorders",
issn = "0165-0327",
publisher = "Elsevier",

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TY - JOUR

T1 - Prevalence and sociodemographic patterns of antidepressant use among women of reproductive age: a prescription database study.

AU - Dolk, Helen

AU - Wemakor, Anthony

AU - Casson, K.

PY - 2014/6/19

Y1 - 2014/6/19

N2 - BACKGROUND:There has been a steady increase in the prescription of antidepressants in developed countries in recent decades. Antidepressant treatment prevalence and sociodemographic pattern data can inform the review of clinical guidelines for depression treatment. We determined the one-year prevalence and sociodemographic pattern of antidepressant dispensing among women of childbearing age (15-45 years) in Northern Ireland (NI).METHODS:A cross-sectional study using individual electronic prescribing data for 2009. Our study population was 268,917 women of childbearing age (15-45 years), with/without prescriptions, registered with the 246 out of 363GP practices in NI with high electronic prescribing data coverage. Socioeconomic deprivation (in quintiles) was measured by an area indicator attached to residential postcode.RESULTS:The one-year prevalence of redeemed antidepressant prescriptions was 16.3% (95% CI 16.1-16.4). More than two-thirds of antidepressant prescriptions were for SSRIs. Thirty-five per cent of the women who redeemed prescriptions for antidepressants also redeemed prescriptions for psycholeptics within 2 months of the antidepressant prescriptions. Redeemed antidepressant prescription prevalence increased from 4.8% (15-19 years) to 24.6% (40-45 years), from 13.5% (quintile 1, least deprived) to 20.7% (quintile 5, most deprived), and with urbanity of GP practice location.LIMITATION:Only GP practices with high capture of electronic prescribing data were included, which may not be entirely representative of NI. We could not assess the appropriateness of prescribing according to national guidelines.CONCLUSIONS:Antidepressant use is high among women of childbearing age in NI and increases with age and socioeconomic deprivation. This reinforces the need to address the determinants of depression, and assess the appropriateness of treatment policies and practices.

AB - BACKGROUND:There has been a steady increase in the prescription of antidepressants in developed countries in recent decades. Antidepressant treatment prevalence and sociodemographic pattern data can inform the review of clinical guidelines for depression treatment. We determined the one-year prevalence and sociodemographic pattern of antidepressant dispensing among women of childbearing age (15-45 years) in Northern Ireland (NI).METHODS:A cross-sectional study using individual electronic prescribing data for 2009. Our study population was 268,917 women of childbearing age (15-45 years), with/without prescriptions, registered with the 246 out of 363GP practices in NI with high electronic prescribing data coverage. Socioeconomic deprivation (in quintiles) was measured by an area indicator attached to residential postcode.RESULTS:The one-year prevalence of redeemed antidepressant prescriptions was 16.3% (95% CI 16.1-16.4). More than two-thirds of antidepressant prescriptions were for SSRIs. Thirty-five per cent of the women who redeemed prescriptions for antidepressants also redeemed prescriptions for psycholeptics within 2 months of the antidepressant prescriptions. Redeemed antidepressant prescription prevalence increased from 4.8% (15-19 years) to 24.6% (40-45 years), from 13.5% (quintile 1, least deprived) to 20.7% (quintile 5, most deprived), and with urbanity of GP practice location.LIMITATION:Only GP practices with high capture of electronic prescribing data were included, which may not be entirely representative of NI. We could not assess the appropriateness of prescribing according to national guidelines.CONCLUSIONS:Antidepressant use is high among women of childbearing age in NI and increases with age and socioeconomic deprivation. This reinforces the need to address the determinants of depression, and assess the appropriateness of treatment policies and practices.

KW - Age

KW - Antidepressants

KW - Socioeconomic deprivation

KW - Women of childbearing age

U2 - 10.1016/j.jad.2014.06.015

DO - 10.1016/j.jad.2014.06.015

M3 - Article

VL - 167

SP - 299

EP - 305

JO - Journal of Affective Disorders

T2 - Journal of Affective Disorders

JF - Journal of Affective Disorders

SN - 0165-0327

ER -