Premorbid IQ in patients with functional psychosis and their first-degree relatives.

C Gilvarry, N Takei, A Russell, T Rushe, D Hemsley, R M Murray

    Research output: Contribution to journalArticle

    54 Citations (Scopus)

    Abstract

    Numerous studies have found deficits in premorbid IQ in schizophrenic patients, but it is not clear whether this deficit is shared by (a) patients with other functional psychoses, and (b) relatives of these patients. Ninety-one schizophrenic patients, 66 affective psychotic patients (29 schizoaffective and 37 manic or depressed), and 50 normal control subjects were administered the National Adult Reading Test (NART) which provides an estimate of premorbid IQ. The NART was also completed by 85 first-degree relatives of schizophrenic patients and by 65 first-degree relatives of affective psychotic patients. After adjustments were made for sex, social class, ethnicity and years of education, schizophrenic patients had significantly lower premorbid IQ than their relatives, the affective psychotic patients and controls. Manic and depressed patients had significantly lower NART scores than their first-degree relatives, but schizoaffective patients did not, and neither group differed significantly from controls. There was no significant difference in premorbid IQ between patients who had experienced obstetric complications (OC+) and those who had not (OC-). Both OC+ and OC- schizophrenic patients differed significantly from their relatives, but the disparity was greatest between OC+ patients and their relatives. Relatives of OC+ schizophrenic patients had significantly higher IQ than relatives of OC- schizophrenic patients.
    LanguageEnglish
    Pages417-29
    JournalSchizophrenia Research
    Volume41
    Issue number3
    Publication statusPublished - 2000

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    Psychotic Disorders
    Reading
    Social Adjustment
    Patient Education
    Social Class
    Obstetrics

    Cite this

    Gilvarry, C., Takei, N., Russell, A., Rushe, T., Hemsley, D., & Murray, R. M. (2000). Premorbid IQ in patients with functional psychosis and their first-degree relatives. 41(3), 417-29.
    Gilvarry, C ; Takei, N ; Russell, A ; Rushe, T ; Hemsley, D ; Murray, R M. / Premorbid IQ in patients with functional psychosis and their first-degree relatives. 2000 ; Vol. 41, No. 3. pp. 417-29.
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    Gilvarry, C, Takei, N, Russell, A, Rushe, T, Hemsley, D & Murray, RM 2000, 'Premorbid IQ in patients with functional psychosis and their first-degree relatives.', vol. 41, no. 3, pp. 417-29.

    Premorbid IQ in patients with functional psychosis and their first-degree relatives. / Gilvarry, C; Takei, N; Russell, A; Rushe, T; Hemsley, D; Murray, R M.

    Vol. 41, No. 3, 2000, p. 417-29.

    Research output: Contribution to journalArticle

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    Gilvarry C, Takei N, Russell A, Rushe T, Hemsley D, Murray RM. Premorbid IQ in patients with functional psychosis and their first-degree relatives. 2000;41(3):417-29.