Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases

Pilar Rivera Ortega; Alexis Papadopoulos; Julie Martin; Christopher Craig; Andrew Cheng; Conal Hayton; Colm Leonard; Nazia Chaudhuri; Angeles Montero

doi:10.1183/13993003.congress-2019.PA4790

Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases

Pilar Rivera Ortega
, Alexis Papadopoulos
, Julie Martin
, Christopher Craig
, Andrew Cheng
, Conal Hayton
, Colm Leonard
, Nazia Chaudhuri
, Angeles Montero

Research output: Contribution to journal › Conference article › peer-review

Abstract

Introduction: Bronchoalveolar lavage (BAL) is a well-recognised diagnostic tool in patients with Interstitial Lung Disease (ILD). According to the guidelines published by the American Thoracic Society/European Respiratory Society, a BAL is considered of adequate quality when percentage of other cells (epithelial/columnar cells) is <5%.

Objectives: Determine the predictive variables for obtaining BAL of adequate quality in ILD patients.

Methods: Retrospective study of all BALs performed from August 2018 to January 2019 on a dedicated ILD bronchoscopy list of a thoracic referral centre in the United Kingdom. Demographic, clinical, computed tomography (CT) pattern, procedure technique and histopathological data were collected.

Results: 63 BALs were performed (27 women and 36 men, mean age of 63 years-old). We obtained adequate BAL quality in 19 patients (30%). Table 1 shows all the variables evaluated according to the quality of BAL. The absence of smoking history and the CT pattern of indeterminate for usual interstitial pneumonia were independent variables associated with an adequate BAL quality (p-value of 0.05 and 0.02, respectively).

Conclusion: Smoking history and CT pattern could influence the BAL quality, regardless of lung function and procedure technique.

Original language	English
Article number	PA4790
Journal	European Respiratory Journal
Volume	54
Issue number	Suppl 63
DOIs	https://doi.org/10.1183/13993003.congress-2019.PA4790
Publication status	Published online - 21 Nov 2019

Bibliographical note

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

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10.1183/13993003.congress-2019.PA4790

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Rivera Ortega, P., Papadopoulos, A., Martin, J., Craig, C., Cheng, A., Hayton, C., Leonard, C., Chaudhuri, N., & Montero, A. (2019). Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases. European Respiratory Journal, 54(Suppl 63), Article PA4790. Advance online publication. https://doi.org/10.1183/13993003.congress-2019.PA4790

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title = "Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases",

abstract = "Introduction: Bronchoalveolar lavage (BAL) is a well-recognised diagnostic tool in patients with Interstitial Lung Disease (ILD). According to the guidelines published by the American Thoracic Society/European Respiratory Society, a BAL is considered of adequate quality when percentage of other cells (epithelial/columnar cells) is <5\%. Objectives: Determine the predictive variables for obtaining BAL of adequate quality in ILD patients. Methods: Retrospective study of all BALs performed from August 2018 to January 2019 on a dedicated ILD bronchoscopy list of a thoracic referral centre in the United Kingdom. Demographic, clinical, computed tomography (CT) pattern, procedure technique and histopathological data were collected. Results: 63 BALs were performed (27 women and 36 men, mean age of 63 years-old). We obtained adequate BAL quality in 19 patients (30\%). Table 1 shows all the variables evaluated according to the quality of BAL. The absence of smoking history and the CT pattern of indeterminate for usual interstitial pneumonia were independent variables associated with an adequate BAL quality (p-value of 0.05 and 0.02, respectively). Conclusion: Smoking history and CT pattern could influence the BAL quality, regardless of lung function and procedure technique.",

author = "\{Rivera Ortega\}, Pilar and Alexis Papadopoulos and Julie Martin and Christopher Craig and Andrew Cheng and Conal Hayton and Colm Leonard and Nazia Chaudhuri and Angeles Montero",

note = "This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).",

year = "2019",

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doi = "10.1183/13993003.congress-2019.PA4790",

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TY - JOUR

T1 - Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases

AU - Rivera Ortega, Pilar

AU - Papadopoulos, Alexis

AU - Martin, Julie

AU - Craig, Christopher

AU - Cheng, Andrew

AU - Hayton, Conal

AU - Leonard, Colm

AU - Chaudhuri, Nazia

AU - Montero, Angeles

N1 - This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

PY - 2019/11/21

Y1 - 2019/11/21

N2 - Introduction: Bronchoalveolar lavage (BAL) is a well-recognised diagnostic tool in patients with Interstitial Lung Disease (ILD). According to the guidelines published by the American Thoracic Society/European Respiratory Society, a BAL is considered of adequate quality when percentage of other cells (epithelial/columnar cells) is <5%. Objectives: Determine the predictive variables for obtaining BAL of adequate quality in ILD patients. Methods: Retrospective study of all BALs performed from August 2018 to January 2019 on a dedicated ILD bronchoscopy list of a thoracic referral centre in the United Kingdom. Demographic, clinical, computed tomography (CT) pattern, procedure technique and histopathological data were collected. Results: 63 BALs were performed (27 women and 36 men, mean age of 63 years-old). We obtained adequate BAL quality in 19 patients (30%). Table 1 shows all the variables evaluated according to the quality of BAL. The absence of smoking history and the CT pattern of indeterminate for usual interstitial pneumonia were independent variables associated with an adequate BAL quality (p-value of 0.05 and 0.02, respectively). Conclusion: Smoking history and CT pattern could influence the BAL quality, regardless of lung function and procedure technique.

AB - Introduction: Bronchoalveolar lavage (BAL) is a well-recognised diagnostic tool in patients with Interstitial Lung Disease (ILD). According to the guidelines published by the American Thoracic Society/European Respiratory Society, a BAL is considered of adequate quality when percentage of other cells (epithelial/columnar cells) is <5%. Objectives: Determine the predictive variables for obtaining BAL of adequate quality in ILD patients. Methods: Retrospective study of all BALs performed from August 2018 to January 2019 on a dedicated ILD bronchoscopy list of a thoracic referral centre in the United Kingdom. Demographic, clinical, computed tomography (CT) pattern, procedure technique and histopathological data were collected. Results: 63 BALs were performed (27 women and 36 men, mean age of 63 years-old). We obtained adequate BAL quality in 19 patients (30%). Table 1 shows all the variables evaluated according to the quality of BAL. The absence of smoking history and the CT pattern of indeterminate for usual interstitial pneumonia were independent variables associated with an adequate BAL quality (p-value of 0.05 and 0.02, respectively). Conclusion: Smoking history and CT pattern could influence the BAL quality, regardless of lung function and procedure technique.

U2 - 10.1183/13993003.congress-2019.PA4790

DO - 10.1183/13993003.congress-2019.PA4790

M3 - Conference article

SN - 0903-1936

VL - 54

JO - European Respiratory Journal

JF - European Respiratory Journal

IS - Suppl 63

M1 - PA4790

ER -

Predictive variables to obtain a bronchoalveolar lavage of adequate quality in patients with interstitial lung diseases

Abstract

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