Multi-channeled nerve guidance conduit is a prospective way to repair peripheral nerve injury, which is still difficult to be fabricated. A novel extrusion-stretching method was utilized in this study to produce multi-walled carbon nanotubes (MWCNTs) loaded multi-channeled nerve conduits with improved flexibility and versatility. The channels and geography of the conduits were tunable. The results showed that the mechanical properties of the multi-channeled nerve conduits were suitable for peripheral nerve restoration. MWCNTs increased the biocompatibility of the multi-channeled nerve conduits. This study proved that the MWCNTs loaded multi-channeled produced by extrusion-stretching method have great potential to repair peripheral nerve injury.
|Number of pages||9|
|Journal||International Journal of Polymeric Materials and Polymeric Biomaterials|
|Early online date||6 Apr 2023|
|Publication status||Published online - 6 Apr 2023|
Bibliographical notePublisher Copyright:
© 2023 Taylor & Francis Group, LLC.
- Polymers and Plastics
- General Chemical Engineering
- Analytical Chemistry
- Extrusion-stretching method
- peripheral nerve repair
- nerve guidance conduits