Plasma-Polyplumbagin modified microfiber probes: a functional material approach to monitoring vascular access line contamination

J Davis, MT Molina, CP Leach, MF Cardosi

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Atmospheric plasma treated carbon fiber filaments (10 micron) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood.
    LanguageEnglish
    JournalACS Applied Materials and Interfaces
    VolumeWeb
    DOIs
    Publication statusPublished - 25 Sep 2013

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    Functional materials
    Contamination
    Plasmas
    Monitoring
    Polymers
    Blood
    Composite materials
    Substrates
    Oxidation-Reduction

    Cite this

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    abstract = "Atmospheric plasma treated carbon fiber filaments (10 micron) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood.",
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    Plasma-Polyplumbagin modified microfiber probes: a functional material approach to monitoring vascular access line contamination. / Davis, J; Molina, MT; Leach, CP; Cardosi, MF.

    In: ACS Applied Materials and Interfaces, Vol. Web, 25.09.2013.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Plasma-Polyplumbagin modified microfiber probes: a functional material approach to monitoring vascular access line contamination

    AU - Davis, J

    AU - Molina, MT

    AU - Leach, CP

    AU - Cardosi, MF

    PY - 2013/9/25

    Y1 - 2013/9/25

    N2 - Atmospheric plasma treated carbon fiber filaments (10 micron) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood.

    AB - Atmospheric plasma treated carbon fiber filaments (10 micron) were used as the base substrate in the design of a probe intended for use within intravascular access devices. The microfiber probe was further functionalized with a polyplumbagin layer through which the line pH could be determined voltammetrically and therein provide the potential for obtaining diagnostic information relating to bacterial colonization of the line. The redox processes attributed to the immobilized polymer are characterized and a methodology developed to enable the acquisition of a redox signal that is selective and sensitive to pH. The applicability of the composite probe was demonstrated through examining the direct response in whole blood.

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    DO - 10.1021/am402821c,

    M3 - Article

    VL - Web

    JO - ACS Applied Materials and Interfaces

    T2 - ACS Applied Materials and Interfaces

    JF - ACS Applied Materials and Interfaces

    SN - 1944-8244

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