Plasma ascorbate and vitamin E levels in Hong Kong Chinese

IFF Benzie, ED Janusz, JJ Strain

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective: To describe fasting plasma total-and lipid standardised-vitamin E and ascorbate concentrations in Hong Kong Chinese subjects, and to explore age-, diet- and sex-related differences. Design: Observational study. Setting: Hong Kong. Subjects: One hundred and fifty randomly selected Chinese subjects. Interventions: Fasting plasma concentrations of ascorbate, total vitamin E and lipid standardised vitamin E (Vit E-LS expressed as mu mol vitamin E/mmol total cholesterol plus triglycerides) were measured. Results: Total vitamin E concentrations ranged from 6-53 mu mol/l (mean 24; s.d. 8.5), and Vit E-LS from 0.85-7.09 mu mol/mmol (mean 3.61; s.d. 1.19). Plasma Vit E-LS concentrations in women were higher (P = 0.02) than in men: mean (median) concentrations 3.82 (3.88) and 3.37 (3.28) mu mol/mmol, respectively. Vit E-LS concentrations in men decreased with age. Mean (s.d.) plasma ascorbate concentrations in men and women were 49.7 (14.0) and 51.6 (21.6) mu mol/l respectively, and did not show the significant age-and sex-differences reportedly found in Western studies. Conclusions: The hypothesis that Hong Kong Chinese, with their low risk of CHD, might have high Vit E-LS levels in fasting plasma is not supported by the results obtained. Moreover, results showed male-female differences and, in men, a previously unreported age-related decrease in plasma Vit E-LS concentration which cannot be accounted for by concomitant differences in dietary intake of vitamin E alone. Results also suggest that the age-and sex-differences in plasma ascorbate seen in Western populations can be avoided by increased vitamin C intake.
LanguageEnglish
Pages447-451
JournalEuropean Journal of Clinical Nutrition
Volume52
Issue number6
Publication statusPublished - Jun 1998

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Hong Kong
Vitamin E
Sex Characteristics
Fasting
Lipids
Tocopherols
Ascorbic Acid
Observational Studies
Triglycerides
Cholesterol
Diet
Population

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title = "Plasma ascorbate and vitamin E levels in Hong Kong Chinese",
abstract = "Objective: To describe fasting plasma total-and lipid standardised-vitamin E and ascorbate concentrations in Hong Kong Chinese subjects, and to explore age-, diet- and sex-related differences. Design: Observational study. Setting: Hong Kong. Subjects: One hundred and fifty randomly selected Chinese subjects. Interventions: Fasting plasma concentrations of ascorbate, total vitamin E and lipid standardised vitamin E (Vit E-LS expressed as mu mol vitamin E/mmol total cholesterol plus triglycerides) were measured. Results: Total vitamin E concentrations ranged from 6-53 mu mol/l (mean 24; s.d. 8.5), and Vit E-LS from 0.85-7.09 mu mol/mmol (mean 3.61; s.d. 1.19). Plasma Vit E-LS concentrations in women were higher (P = 0.02) than in men: mean (median) concentrations 3.82 (3.88) and 3.37 (3.28) mu mol/mmol, respectively. Vit E-LS concentrations in men decreased with age. Mean (s.d.) plasma ascorbate concentrations in men and women were 49.7 (14.0) and 51.6 (21.6) mu mol/l respectively, and did not show the significant age-and sex-differences reportedly found in Western studies. Conclusions: The hypothesis that Hong Kong Chinese, with their low risk of CHD, might have high Vit E-LS levels in fasting plasma is not supported by the results obtained. Moreover, results showed male-female differences and, in men, a previously unreported age-related decrease in plasma Vit E-LS concentration which cannot be accounted for by concomitant differences in dietary intake of vitamin E alone. Results also suggest that the age-and sex-differences in plasma ascorbate seen in Western populations can be avoided by increased vitamin C intake.",
author = "IFF Benzie and ED Janusz and JJ Strain",
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Plasma ascorbate and vitamin E levels in Hong Kong Chinese. / Benzie, IFF; Janusz, ED; Strain, JJ.

In: European Journal of Clinical Nutrition, Vol. 52, No. 6, 06.1998, p. 447-451.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Plasma ascorbate and vitamin E levels in Hong Kong Chinese

AU - Benzie, IFF

AU - Janusz, ED

AU - Strain, JJ

PY - 1998/6

Y1 - 1998/6

N2 - Objective: To describe fasting plasma total-and lipid standardised-vitamin E and ascorbate concentrations in Hong Kong Chinese subjects, and to explore age-, diet- and sex-related differences. Design: Observational study. Setting: Hong Kong. Subjects: One hundred and fifty randomly selected Chinese subjects. Interventions: Fasting plasma concentrations of ascorbate, total vitamin E and lipid standardised vitamin E (Vit E-LS expressed as mu mol vitamin E/mmol total cholesterol plus triglycerides) were measured. Results: Total vitamin E concentrations ranged from 6-53 mu mol/l (mean 24; s.d. 8.5), and Vit E-LS from 0.85-7.09 mu mol/mmol (mean 3.61; s.d. 1.19). Plasma Vit E-LS concentrations in women were higher (P = 0.02) than in men: mean (median) concentrations 3.82 (3.88) and 3.37 (3.28) mu mol/mmol, respectively. Vit E-LS concentrations in men decreased with age. Mean (s.d.) plasma ascorbate concentrations in men and women were 49.7 (14.0) and 51.6 (21.6) mu mol/l respectively, and did not show the significant age-and sex-differences reportedly found in Western studies. Conclusions: The hypothesis that Hong Kong Chinese, with their low risk of CHD, might have high Vit E-LS levels in fasting plasma is not supported by the results obtained. Moreover, results showed male-female differences and, in men, a previously unreported age-related decrease in plasma Vit E-LS concentration which cannot be accounted for by concomitant differences in dietary intake of vitamin E alone. Results also suggest that the age-and sex-differences in plasma ascorbate seen in Western populations can be avoided by increased vitamin C intake.

AB - Objective: To describe fasting plasma total-and lipid standardised-vitamin E and ascorbate concentrations in Hong Kong Chinese subjects, and to explore age-, diet- and sex-related differences. Design: Observational study. Setting: Hong Kong. Subjects: One hundred and fifty randomly selected Chinese subjects. Interventions: Fasting plasma concentrations of ascorbate, total vitamin E and lipid standardised vitamin E (Vit E-LS expressed as mu mol vitamin E/mmol total cholesterol plus triglycerides) were measured. Results: Total vitamin E concentrations ranged from 6-53 mu mol/l (mean 24; s.d. 8.5), and Vit E-LS from 0.85-7.09 mu mol/mmol (mean 3.61; s.d. 1.19). Plasma Vit E-LS concentrations in women were higher (P = 0.02) than in men: mean (median) concentrations 3.82 (3.88) and 3.37 (3.28) mu mol/mmol, respectively. Vit E-LS concentrations in men decreased with age. Mean (s.d.) plasma ascorbate concentrations in men and women were 49.7 (14.0) and 51.6 (21.6) mu mol/l respectively, and did not show the significant age-and sex-differences reportedly found in Western studies. Conclusions: The hypothesis that Hong Kong Chinese, with their low risk of CHD, might have high Vit E-LS levels in fasting plasma is not supported by the results obtained. Moreover, results showed male-female differences and, in men, a previously unreported age-related decrease in plasma Vit E-LS concentration which cannot be accounted for by concomitant differences in dietary intake of vitamin E alone. Results also suggest that the age-and sex-differences in plasma ascorbate seen in Western populations can be avoided by increased vitamin C intake.

M3 - Article

VL - 52

SP - 447

EP - 451

JO - European Journal of Clinical Nutrition

T2 - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

IS - 6

ER -