Physical activity, lipids, apolipoproteins, and Lp(a) in the Northern Ireland Health and Activity Survey

D MacAuley, EE McCrum, G Stott, AE Evans, E Duly, TR Trinick, K Sweeney, CAG Boreham

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    Abstract

    In a cross-sectional study using a two-stage probability sample (N = 1,600) of the population of Northern Ireland, there was an inverse association between the highest recorded recent activity and total cholesterol (P less than or equal to 0.01), LDL (P less than or equal to 0.01), triglyceride (P less than or equal to 0.05) and Chol:HDL ratio (P less than or equal to 0.001) in males, and total cholesterol (P less than or equal to 0.001), LDL (P less than or equal to 0.001), and triglyceride (P less than or equal to 0.01) in females; between habitual activity and HDL (P less than or equal to 0.05) in males and total cholesterol (P less than or equal to 0.05) and triglyceride (P less than or equal to 0.01) in females. There was a relationship between the highest recorded activity and apoAI (P less than or equal to 0.01) and apoB (P less than or equal to 0.01) in males and with apoB (P less than or equal to 0.001) in females; between habitual activity and apoAI (P less than or equal to 0.01) and apoAII (P less than or equal to 0.05) in males and apoB (P less than or equal to 0.01) in females; between past activity and Lp(a) in females (P less than or equal to 0.05). After adjustment for possible confounding factors, total cholesterol (P less than or equal to 0.05) and LDL (P less than or equal to 0.05) were unexpectedly higher in males who were active throughout life. Total cholesterol (P less than or equal to 0.05) and LDL (P less than or equal to 0.001) were higher in females with highest recorded activity and triglycerides lower (P less than or equal to 0.05) in those habitually active. An association between highest recorded activity and apoAI (P less than or equal to 0.01), and past activity and apoAI:apoB ratio (P less than or equal to 0.05) was shown in males and in females, after adjustment, and between apoB (P less than or equal to 0.05) and highest recorded activity.
    Original languageEnglish
    Pages (from-to)720-736
    JournalMedicine and Science in Sports and Exercise
    Volume28
    Issue number6
    Publication statusPublished (in print/issue) - Jun 1996

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