TY - JOUR
T1 - Pharmacological effects of natural Ganoderma and its extracts on neurological diseases
T2 - A comprehensive review
AU - Zhao, Chen
AU - Zhang, Chunchen
AU - Xing, Zheng
AU - Ahmad, Zeeshan
AU - Li, Jing Song
AU - Chang, Ming Wei
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Ganoderma, has been used for clinical applications for thousands of years as a highly-nutritious and significantly-effective medicinal herb. The active components and efficacy of Ganoderma are constantly being explored and supplemented every year. In recent years, more and more literature has reported the pharmacological effects of Ganoderma on anti-tumor, liver protection and immunity enhancement, especially on neuroprotection. Numerous research works on the neuroprotective effects of Ganoderma have been documented (e.g., modulation of neurogenesis, amelioration of Alzheimer's disease, therapeutic effect on epilepsy, the protective effect on neural cells in stroke injury, etc.) thus it has drawn increasing attention. However, an integrated and comprehensive review of recent research findings has not been detailed in any great depth. Therefore, the purpose of this review is to summarize and elucidate recent progress of neuroprotective effects of natural Ganoderma and its extracts.
AB - Ganoderma, has been used for clinical applications for thousands of years as a highly-nutritious and significantly-effective medicinal herb. The active components and efficacy of Ganoderma are constantly being explored and supplemented every year. In recent years, more and more literature has reported the pharmacological effects of Ganoderma on anti-tumor, liver protection and immunity enhancement, especially on neuroprotection. Numerous research works on the neuroprotective effects of Ganoderma have been documented (e.g., modulation of neurogenesis, amelioration of Alzheimer's disease, therapeutic effect on epilepsy, the protective effect on neural cells in stroke injury, etc.) thus it has drawn increasing attention. However, an integrated and comprehensive review of recent research findings has not been detailed in any great depth. Therefore, the purpose of this review is to summarize and elucidate recent progress of neuroprotective effects of natural Ganoderma and its extracts.
KW - Ganoderma
KW - Neurological diseases
KW - Traditional Chinese medicine
UR - http://www.scopus.com/inward/record.url?scp=85055265804&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2018.10.076
DO - 10.1016/j.ijbiomac.2018.10.076
M3 - Review article
C2 - 30342128
AN - SCOPUS:85055265804
SN - 0141-8130
VL - 121
SP - 1160
EP - 1178
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -