TY - JOUR
T1 - Pharmaceutical and biomaterial engineering via electrohydrodynamic atomization technologies
AU - Mehta, Prina
AU - Haj-Ahmad, Rita
AU - Rasekh, Manoochehr
AU - Arshad, Muhammad S.
AU - Smith, Ashleigh
AU - van der Merwe, Susanna M.
AU - Li, Xiang
AU - Chang, Ming Wei
AU - Ahmad, Zeeshan
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Complex micro- and nano-structures enable crucial developments in the healthcare remit (e.g., pharmaceutical and biomaterial sciences). In recent times, several technologies have been developed and explored to address key healthcare challenges (e.g., advanced chemotherapy, biomedical diagnostics and tissue regeneration). Electrohydrodynamic atomization (EHDA) technologies are rapidly emerging as promising candidates to address these issues. The fundamental principle driving EHDA engineering relates to the action of an electric force (field) on flowing conducting medium (formulation) giving rise to a stable Taylor cone. Through careful optimization of process parameters, material properties and selection, nozzle and needle design, and collection substrate method, complex active micro- and nano-structures are engineered. This short review focuses on key selected recent and established advances in the field of pharmaceutical and biomaterial applications.
AB - Complex micro- and nano-structures enable crucial developments in the healthcare remit (e.g., pharmaceutical and biomaterial sciences). In recent times, several technologies have been developed and explored to address key healthcare challenges (e.g., advanced chemotherapy, biomedical diagnostics and tissue regeneration). Electrohydrodynamic atomization (EHDA) technologies are rapidly emerging as promising candidates to address these issues. The fundamental principle driving EHDA engineering relates to the action of an electric force (field) on flowing conducting medium (formulation) giving rise to a stable Taylor cone. Through careful optimization of process parameters, material properties and selection, nozzle and needle design, and collection substrate method, complex active micro- and nano-structures are engineered. This short review focuses on key selected recent and established advances in the field of pharmaceutical and biomaterial applications.
UR - http://www.scopus.com/inward/record.url?scp=85008686506&partnerID=8YFLogxK
U2 - 10.1016/j.drudis.2016.09.021
DO - 10.1016/j.drudis.2016.09.021
M3 - Review article
C2 - 27693432
AN - SCOPUS:85008686506
SN - 1359-6446
VL - 22
SP - 157
EP - 165
JO - Drug Discovery Today
JF - Drug Discovery Today
IS - 1
ER -