Patient-reported outcome measures (PROMs) after laparoscopic cholecystectomy: systematic review

Conor Melly, Gearoid McGeehan, Niall O’Connor, Alison Johnston, Gary Bass, Shahin Mohseni, Claire Donohoe, Magda Bucholc, Michael Sugrue

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)
92 Downloads (Pure)


Healthcare requires patient feedback to improve outcomes and experience. This study undertook a systematic review of the depth, variability, and digital suitability of current patient-reported outcome measures (PROMs) in patients undergoing laparoscopic cholecystectomy.

A PROSPERO-registered (registration number CRD42021261707) systematic review was undertaken for all relevant English language articles using PubMed version of MEDLINE, Scopus, and Web of Science electronic databases in June 2021. The search used Boolean operators and wildcards and included the keywords: laparoscopic cholecystectomy AND patient outcome OR patient-reported outcome OR patient-reported outcome measure OR PRO OR PROM. Medical Subjects Heading terms were used to search PubMed and Scopus. Articles published from 1 January 2011 to 2 June 2021 were included.

A total of 4960 individual articles were reviewed in this study, of which 44 were found to evaluate PROMs in patients undergoing laparoscopic cholecystectomy and underwent methodological index for non-randomized studies (MINORS) grading. Twenty-one articles spanning 19 countries and four continents met all inclusion criteria and were included in the qualitative data synthesis. There was significant heterogeneity in PROMs identified with eight different comprehensive PROM tools used in the 21 studies. There was wide variation in the time points at which PROMs were recorded. Fourteen of 21 studies recorded PROMs before and after surgery, and 7 of 21 recorded PROMs only after surgery. Follow-up intervals ranged from 3 days to 2 years after surgery.

This study identified that while post-laparoscopic cholecystectomy PROMs are infrequently measured currently, tools are widely available to achieve this in clinical practice. PROMs may not capture all the outcomes but should be incorporated into future cholecystectomy outcome research. The EQ-5D™ (EuroQoL Group, Rotterdam, the Netherlands) provides a simple platform for the modern digital era.
Original languageEnglish
Article numberzrac062
Pages (from-to)1-11
Number of pages11
JournalBJS Open
Issue number3
Publication statusPublished (in print/issue) - 1 Jun 2022

Bibliographical note

Funding Information:
This project was supported by the European Union's INTERREG VA Programme, managed by the Special EU Programmes Body, and Donegal Clinical and Research Academy and Professor William Campbell Nobel Laureate Scholarship.

Publisher Copyright:
© The Author(s) 2022.


  • General Medicine


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