Outdoor air pollution and infant mortality: analysis of daily time-series data in 10 English cities

S Hajat, B Armstrong, P Wilkinson, A Busby, Helen Dolk

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Background: There is growing concern that moderate levels of outdoor air pollution may be associated with infant mortality, representing substantial loss of life-years. To date, there has been no investigation of the effects of outdoor pollution on infant mortality in the UK. Methods: Daily time-series data of air pollution and all infant deaths between 1990 and 2000 in 10 major cities of England: Birmingham, Bristol, Leeds, Liverpool, London, Manchester, Middlesbrough, Newcastle, Nottingham and Sheffield, were analysed. City-specific estimates were pooled across cities in a fixed-effects meta-regression to provide a mean estimate. Results: Few associations were observed between infant deaths and most pollutants studied. The exception was sulphur dioxide (SO2), of which a 10 μg/m3 increase was associated with a RR of 1.02 (95% CI 1.01 to 1.04) in all infant deaths. The effect was present in both neonatal and postneonatal deaths. Conclusions: Continuing reductions in SO2 levels in the UK may yield additional health benefits for infants.
LanguageEnglish
Pages719-722
JournalJournal of Epidemiology and Community Health
Volume61
Issue number8
DOIs
Publication statusPublished - 2007

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Air Pollution
Infant Mortality
Sulfur Dioxide
Insurance Benefits
England
Infant Death

Cite this

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title = "Outdoor air pollution and infant mortality: analysis of daily time-series data in 10 English cities",
abstract = "Background: There is growing concern that moderate levels of outdoor air pollution may be associated with infant mortality, representing substantial loss of life-years. To date, there has been no investigation of the effects of outdoor pollution on infant mortality in the UK. Methods: Daily time-series data of air pollution and all infant deaths between 1990 and 2000 in 10 major cities of England: Birmingham, Bristol, Leeds, Liverpool, London, Manchester, Middlesbrough, Newcastle, Nottingham and Sheffield, were analysed. City-specific estimates were pooled across cities in a fixed-effects meta-regression to provide a mean estimate. Results: Few associations were observed between infant deaths and most pollutants studied. The exception was sulphur dioxide (SO2), of which a 10 μg/m3 increase was associated with a RR of 1.02 (95{\%} CI 1.01 to 1.04) in all infant deaths. The effect was present in both neonatal and postneonatal deaths. Conclusions: Continuing reductions in SO2 levels in the UK may yield additional health benefits for infants.",
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Outdoor air pollution and infant mortality: analysis of daily time-series data in 10 English cities. / Hajat, S; Armstrong, B; Wilkinson, P; Busby, A; Dolk, Helen.

In: Journal of Epidemiology and Community Health, Vol. 61, No. 8, 2007, p. 719-722.

Research output: Contribution to journalArticle

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AU - Armstrong, B

AU - Wilkinson, P

AU - Busby, A

AU - Dolk, Helen

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AB - Background: There is growing concern that moderate levels of outdoor air pollution may be associated with infant mortality, representing substantial loss of life-years. To date, there has been no investigation of the effects of outdoor pollution on infant mortality in the UK. Methods: Daily time-series data of air pollution and all infant deaths between 1990 and 2000 in 10 major cities of England: Birmingham, Bristol, Leeds, Liverpool, London, Manchester, Middlesbrough, Newcastle, Nottingham and Sheffield, were analysed. City-specific estimates were pooled across cities in a fixed-effects meta-regression to provide a mean estimate. Results: Few associations were observed between infant deaths and most pollutants studied. The exception was sulphur dioxide (SO2), of which a 10 μg/m3 increase was associated with a RR of 1.02 (95% CI 1.01 to 1.04) in all infant deaths. The effect was present in both neonatal and postneonatal deaths. Conclusions: Continuing reductions in SO2 levels in the UK may yield additional health benefits for infants.

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