Oral Adjuvant Therapy for Colorectal Cancer: Recent Developments and Future Targets

Aliasgar Shahiwala, Samar Salam Qawoogha, Murtaza M Tambuwala

Research output: Contribution to journalReview article

Abstract

Colorectal cancer is considered the third most frequent malignant neoplasm occurring in both men and women worldwide. Most approaches that have been used to fight and treat this type of malignancy are either invasive or nonselective. Noninvasive therapy using oral route can increase patient compliance and reduce treatment costs. Innovative measures such as use of nanotechnology and theranostic systems have been initiated in the oral therapy, which has been proven to be greatly advantageous in decreasing side effects, improving detection and diagnoses. This manuscript investigates recent innovative and novel therapeutic approaches through oral route and potential targets in the treatment of colorectal cancer.

Original languageEnglish
Pages (from-to)659-669
Number of pages11
JournalTherapeutic Delivery
Volume10
Issue number10
Early online date8 Nov 2019
DOIs
Publication statusE-pub ahead of print - 8 Nov 2019

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Keywords

  • oral therapy
  • Colorectal Cancer
  • targeted therapy
  • oral chemotherapy
  • colorectal cancer
  • immunotherapy
  • nanotechnology
  • theranostic systems
  • monoclonal antibodies

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