Novel refractive index biosensing of microcontact printed molecules on lithium niobate

Nikhil Bhalla, Shivani Sathish, Amy Q. Shen

Research output: Contribution to conferencePaper

Abstract

This work demonstrates, for the first time, the use of lithium niobate as a biosensor that detects local refractive index changes triggered by the presence of biomolecules on its surface. The sensitivity of the sensor was found to be 242±16 nm/RIU. As a case study, we immobilized proteins (IgG antibodies) using micro-contact printing to demonstrate sensing capabilities of the device. The validated proof of concept lays a foundation for developing lithium niobate based novel optical biosensors.

Conference

Conference2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Period16/08/1620/08/16

Fingerprint

Biosensors
Refractive index
Immobilized Proteins
Molecules
Biomolecules
Printing
Immunoglobulin G
Antibodies
Sensors
lithium niobate

Cite this

Bhalla, N., Sathish, S., & Shen, A. Q. (2016). Novel refractive index biosensing of microcontact printed molecules on lithium niobate. 2095-2098. Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), . https://doi.org/10.1109/EMBC.2016.7591141
Bhalla, Nikhil ; Sathish, Shivani ; Shen, Amy Q. / Novel refractive index biosensing of microcontact printed molecules on lithium niobate. Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), .
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Bhalla, N, Sathish, S & Shen, AQ 2016, 'Novel refractive index biosensing of microcontact printed molecules on lithium niobate' Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 16/08/16 - 20/08/16, pp. 2095-2098. https://doi.org/10.1109/EMBC.2016.7591141

Novel refractive index biosensing of microcontact printed molecules on lithium niobate. / Bhalla, Nikhil; Sathish, Shivani; Shen, Amy Q.

2016. 2095-2098 Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), .

Research output: Contribution to conferencePaper

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Bhalla N, Sathish S, Shen AQ. Novel refractive index biosensing of microcontact printed molecules on lithium niobate. 2016. Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), . https://doi.org/10.1109/EMBC.2016.7591141