Novel refractive index biosensing of microcontact printed molecules on lithium niobate

Nikhil Bhalla, Shivani Sathish, Amy Q. Shen

Research output: Contribution to conferencePaper

Abstract

This work demonstrates, for the first time, the use of lithium niobate as a biosensor that detects local refractive index changes triggered by the presence of biomolecules on its surface. The sensitivity of the sensor was found to be 242±16 nm/RIU. As a case study, we immobilized proteins (IgG antibodies) using micro-contact printing to demonstrate sensing capabilities of the device. The validated proof of concept lays a foundation for developing lithium niobate based novel optical biosensors.
Original languageEnglish
Pages2095-2098
DOIs
Publication statusPublished - 18 Oct 2016
Event2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Orlando, FL, USA
Duration: 16 Aug 201620 Aug 2016

Conference

Conference2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Period16/08/1620/08/16

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    Bhalla, N., Sathish, S., & Shen, A. Q. (2016). Novel refractive index biosensing of microcontact printed molecules on lithium niobate. 2095-2098. Paper presented at 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), . https://doi.org/10.1109/EMBC.2016.7591141