This work demonstrates, for the first time, the use of lithium niobate as a biosensor that detects local refractive index changes triggered by the presence of biomolecules on its surface. The sensitivity of the sensor was found to be 242±16 nm/RIU. As a case study, we immobilized proteins (IgG antibodies) using micro-contact printing to demonstrate sensing capabilities of the device. The validated proof of concept lays a foundation for developing lithium niobate based novel optical biosensors.
|Publication status||Published - 18 Oct 2016|
|Event||2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Orlando, FL, USA|
Duration: 16 Aug 2016 → 20 Aug 2016
|Conference||2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)|
|Period||16/08/16 → 20/08/16|